1995
PERFORIN AND GRANZYME B
McDiarmid S, Farmer D, Kuniyoshi J, Robert M, Khadavi A, Shaked A, Busuttil R. PERFORIN AND GRANZYME B. Transplantation 1995, 59: 762-766. PMID: 7886805, DOI: 10.1097/00007890-199503150-00021.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceBiomarkersBlotting, SouthernCytokinesGraft RejectionGranzymesIntestine, SmallMembrane GlycoproteinsMolecular Sequence DataPerforinPore Forming Cytotoxic ProteinsRatsRats, Inbred BNRats, Inbred LewRNA, MessengerSerine EndopeptidasesT-Lymphocytes, CytotoxicTransplantation, HomologousUp-RegulationConceptsGranzyme BLewis recipientsAllograft groupIsograft controlsPostoperative day 3Reverse transcriptase-polymerase chain reaction methodSemiquantitative reverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reaction methodReverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reactionHistologic rejectionPOD 14Transplant allograftsMild rejectionPOD 3POD 5Killer cellsPOD 10Polymerase chain reaction methodHistologic evidenceTransplant rejectionPolymerase chain reactionF1 donorsHistologic evaluationChain reaction method
1994
Intragraft Expression of Messenger RNA for Interleukin-6 and Tumor Necrosis Factor-α Is a Predictor of Rat Small Intestine Transplant Rejection
Farmer D, McDiarmid S, Kuniyoshi J, Robert M, Shaked A, Busuttil R. Intragraft Expression of Messenger RNA for Interleukin-6 and Tumor Necrosis Factor-α Is a Predictor of Rat Small Intestine Transplant Rejection. Journal Of Surgical Research 1994, 57: 138-142. PMID: 8041128, DOI: 10.1006/jsre.1994.1121.Peer-Reviewed Original ResearchConceptsSmall intestine transplantationInterleukin-6Intragraft expressionPOD 5MRNA expressionIL-6 mRNA expressionRTPCR analysisDetection of rejectionMessenger RNAPostoperative day 3Interleukin-2 receptorTumor necrosis factorUseful diagnostic adjunctTranscriptase-polymerase chain reactionBeta-scintillation countingIntestine transplantationIntestinal histopathologyPOD 8Transplant rejectionPolymerase chain reactionTumor necrosisIL-2RNecrosis factorAllograftsDiagnostic adjunct