2023
Enhanced inhibition of MHC-I expression by SARS-CoV-2 Omicron subvariants
Moriyama M, Lucas C, Monteiro V, Initiative Y, Iwasaki A, Chen N, Breban M, Hahn A, Pham K, Koch T, Chaguza C, Tikhonova I, Castaldi C, Mane S, De Kumar B, Ferguson D, Kerantzas N, Peaper D, Landry M, Schulz W, Vogels C, Grubaugh N. Enhanced inhibition of MHC-I expression by SARS-CoV-2 Omicron subvariants. Proceedings Of The National Academy Of Sciences Of The United States Of America 2023, 120: e2221652120. PMID: 37036977, PMCID: PMC10120007, DOI: 10.1073/pnas.2221652120.Peer-Reviewed Original ResearchConceptsMHC-I expressionBreakthrough infectionsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variantsMajor histocompatibility complex class I expressionCell-mediated immunityInfluenza virus infectionSARS-CoV-2 VOCsMHC-I upregulationClass I expressionSARS-CoV-2T cell recognitionVirus infectionMHC II expressionSpike proteinEnhanced inhibitionInfectionCell recognitionCommon mutationsReinfectionE proteinAntibodiesViral genesSubvariantsExpression
2018
Subacute liver failure due to autochthonous hepatitis E virus infection in an elderly man in the United States
Landry M, Kamili S, Jain D. Subacute liver failure due to autochthonous hepatitis E virus infection in an elderly man in the United States. Human Pathology Reports 2018, 12: 68-70. DOI: 10.1016/j.ehpc.2018.02.007.Peer-Reviewed Original ResearchHepatitis E virus infectionE virus infectionLiver failureElderly menDifferential diagnosisVirus infectionToxic injuryAutochthonous hepatitis E virus infectionAutochthonous hepatitis EAcute hepatitis CAnti-HEV IgMHistologic differential diagnosisANA positivityPanlobular hepatitisSubsequent serologyCholestatic hepatitisHepatitis CHepatitis EBiliary obstructionLiver biopsyImmunocompetent individualsFatal outcomeGenotype 3Early diagnosisAppropriate management
2017
Antiviral Response in the Nasopharynx Identifies Patients With Respiratory Virus Infection
Landry ML, Foxman EF. Antiviral Response in the Nasopharynx Identifies Patients With Respiratory Virus Infection. The Journal Of Infectious Diseases 2017, 217: 897-905. PMID: 29281100, PMCID: PMC5853594, DOI: 10.1093/infdis/jix648.Peer-Reviewed Original ResearchConceptsRespiratory virusesNasopharyngeal swabsViral infectionCXCL10 protein levelsPatient nasopharyngeal swabsRespiratory virus infectionsHuman nasal epithelial cellsManagement of patientsRespiratory virus detectionNasal epithelial cellsSingle host proteinVirus detectionSimple diagnostic testIdentifies patientsRespiratory symptomsRespiratory infectionsRespiratory illnessHigh burdenVirus infectionReceptor RIGCost-effective testAntiviral responseAccurate diagnosisDiagnostic testsInfection
2016
Laboratory Diagnosis of Zika Virus Infection
Landry ML, St George K. Laboratory Diagnosis of Zika Virus Infection. Archives Of Pathology & Laboratory Medicine 2016, 141: 60-67. PMID: 27763787, DOI: 10.5858/arpa.2016-0406-sa.Peer-Reviewed Original ResearchConceptsNucleic acid amplification testsZika virus infectionZika infectionVirus infectionAmplification testsLaboratory diagnosisNucleic acid amplification testingCommercial nucleic acid amplification testsAccurate antibody testZika virus testingPublic health recommendationsEmergency use authorizationAcute infectionAmplification testingSerology resultsPast infectionFlavivirus antigensHealth recommendationsVirus testingCurrent recommendationsAntibody testApplicable diagnostic toolsVirus epitopesAccurate diagnosisInfection
2015
Toscana Virus Encephalitis in a Traveler Returning to the United States
Howell BA, Azar MM, Landry ML, Shaw AC. Toscana Virus Encephalitis in a Traveler Returning to the United States. Journal Of Clinical Microbiology 2015, 53: 1445-1447. PMID: 25673791, PMCID: PMC4365192, DOI: 10.1128/jcm.03498-14.Peer-Reviewed Case Reports and Technical Notes
2013
Hepatitis E virus infection in a liver transplant recipient: delayed diagnosis due to variable performance of serologic assays
Yoo N, Bernstein J, Caldwell C, Dong C, Drobeniuc J, Kamili S, Landry ML. Hepatitis E virus infection in a liver transplant recipient: delayed diagnosis due to variable performance of serologic assays. Transplant Infectious Disease 2013, 15: e166-e168. PMID: 23701647, DOI: 10.1111/tid.12096.Peer-Reviewed Original Research
2007
Serum IgA Antibodies to Epstein-Barr Virus (EBV) Early Lytic Antigens Are Present in Primary EBV Infection
Bhaduri-McIntosh S, Landry ML, Nikiforow S, Rotenberg M, El-Guindy A, Miller G. Serum IgA Antibodies to Epstein-Barr Virus (EBV) Early Lytic Antigens Are Present in Primary EBV Infection. The Journal Of Infectious Diseases 2007, 195: 483-492. PMID: 17230407, DOI: 10.1086/510916.Peer-Reviewed Original ResearchConceptsPrimary EBV infectionSerum IgA antibodiesIgA antibodiesEBV infectionLytic antigensPrimary infectionPrimary Epstein-Barr virus infectionHealthy EBV-seropositive individualsEpstein-Barr virus infectionEB nuclear antigenEBV-seropositive individualsViral capsid antigenAbsence of antibodiesFlow cytometry-based assayLytic EBV replicationCytometry-based assayBurkitt's lymphoma cellsCapsid antigenMucosal sitesEBV replicationIgM antibodiesVirus infectionInfectionLymphoma cellsSerum samples
2003
Suboptimal Detection of Influenza Virus in Adults by the Directigen Flu A+B Enzyme Immunoassay and Correlation of Results with the Number of Antigen-Positive Cells Detected by Cytospin Immunofluorescence
Landry ML, Ferguson D. Suboptimal Detection of Influenza Virus in Adults by the Directigen Flu A+B Enzyme Immunoassay and Correlation of Results with the Number of Antigen-Positive Cells Detected by Cytospin Immunofluorescence. Journal Of Clinical Microbiology 2003, 41: 3407-3409. PMID: 12843105, PMCID: PMC165325, DOI: 10.1128/jcm.41.7.3407-3409.2003.Peer-Reviewed Original ResearchConceptsVirus infectionEnzyme immunoassayDirectigen FluParainfluenza virus infectionPositive EIA resultsRespiratory syncytial virusAntigen-positive cellsNasopharyngeal swabsSyncytial virusEmergency departmentInfluenza diagnosisDirect immunofluorescenceInfluenza virusVirology laboratoryEIA resultsNight shiftsInfectionInfluenzaImmunofluorescenceFluAdultsVirusCorrelation of resultsImmunoassayCells
2000
Respiratory Syncytial Virus Stimulation of Vascular Endothelial Cell Growth Factor/Vascular Permeability Factor
Lee C, Yoon H, Zhu Z, Link H, Wang Z, Gwaltney J, Landry M, Elias J. Respiratory Syncytial Virus Stimulation of Vascular Endothelial Cell Growth Factor/Vascular Permeability Factor. American Journal Of Respiratory Cell And Molecular Biology 2000, 23: 662-669. PMID: 11062145, DOI: 10.1165/ajrcmb.23.5.4188.Peer-Reviewed Original ResearchConceptsVascular endothelial cell growth factorVEGF/VPFRespiratory syncytial virus stimulationRespiratory syncytial virusAcid isoformNormal human bronchial epithelial cellsEndothelial cell growth factorHuman bronchial epithelial cellsUnstimulated A549 cellsVascular permeability factorBronchial epithelial cellsCell growth factorVEGF messenger RNARSV infectionSyncytial virusVirus stimulationNasal washingsVirus infectionSignificant cell cytotoxicityPotent stimulatorCell cytotoxicityGrowth factorElevated levelsPermeability factorA549 cells
1994
Multiple viral infections in the immunocompromised host: recognition and interpretation
Landry M. Multiple viral infections in the immunocompromised host: recognition and interpretation. Journal Of Clinical Virology 1994, 2: 313-321. PMID: 15566777, DOI: 10.1016/0928-0197(94)90001-9.Peer-Reviewed Original ResearchMultiple viral infectionsViral infectionClinical findingsPatient's clinical findingsMultiple test modalitiesImmunocompromised hostEarly recognitionImmunodeficient hostsConcurrent infectionPatient managementSame body siteVirus infectionTransient infectionMultiple virus infectionsLatent infectionCommon virusesBody sitesInfectionSpecimen sourceLaboratory recognitionLaboratory test resultsMore virusesCareful evaluationTest modalitiesMultiple viruses
1989
Rapid and accurate viral diagnosis
Landry ML, Mayo DR, Hsiung GD. Rapid and accurate viral diagnosis. Pharmacology & Therapeutics 1989, 40: 287-328. PMID: 2499895, PMCID: PMC7133644, DOI: 10.1016/0163-7258(89)90098-3.Peer-Reviewed Original Research
1987
Effect of 2'-fluoro-5-methyl-ara-uracil and cyclophosphamide on herpes simplex virus infection in guinea pigs.
Zheng ZM, Landry ML, Mayo DR, Hsiung GD. Effect of 2'-fluoro-5-methyl-ara-uracil and cyclophosphamide on herpes simplex virus infection in guinea pigs. Acta Pharmacologica Sinica 1987, 8: 158-63. PMID: 2959004.Peer-Reviewed Original Research