2015
Functional Trajectories Among Older Persons Before and After Critical Illness
Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM. Functional Trajectories Among Older Persons Before and After Critical Illness. JAMA Internal Medicine 2015, 175: 523-529. PMID: 25665067, PMCID: PMC4467795, DOI: 10.1001/jamainternmed.2014.7889.Peer-Reviewed Original ResearchConceptsIntensive care unitLong-term mortalityCritical illnessICU admissionModerate disabilityOlder personsMinimal disabilitySevere disabilityFunctional trajectoriesFunctional declineEarly deathProspective cohort studyDay of admissionPersons 70 yearsGoals of careRisk of deathShort-term mortalityGreater New HavenSignificant functional declineICU lengthCohort studyHospital dischargePremorbid disabilityCare unitMechanical ventilation
2014
Functional status after critical illness: agreement between patient and proxy assessments
Ahasic AM, Van Ness PH, Murphy TE, Araujo KL, Pisani MA. Functional status after critical illness: agreement between patient and proxy assessments. Age And Ageing 2014, 44: 506-510. PMID: 25324334, PMCID: PMC4411220, DOI: 10.1093/ageing/afu163.Peer-Reviewed Original ResearchConceptsMonths post-ICU dischargePost-ICU dischargeFunctional statusCritical illnessInter-observer agreementICU admissionOlder patientsExact testIntensive care unit admissionProxy assessmentsPremorbid functional statusCare unit admissionBaseline functional statusCurrent functional statusMcNemar's exact testUnit admissionICU dischargeMedical ICUNeuropsychological morbidityInstrumental ADLCognitive dysfunctionDaily livingPatientsCognitive impairmentParent cohort
2011
Disability in activities of daily living, depression, and quality of life among older medical ICU survivors: a prospective cohort study
Vest MT, Murphy TE, Araujo K, Pisani MA. Disability in activities of daily living, depression, and quality of life among older medical ICU survivors: a prospective cohort study. Health And Quality Of Life Outcomes 2011, 9: 9. PMID: 21294911, PMCID: PMC3041645, DOI: 10.1186/1477-7525-9-9.Peer-Reviewed Original ResearchConceptsPost-ICU dischargeQuality of lifeYear post-ICU dischargeOlder ICU survivorsICU survivorsPhysical scoresICU dischargeADL disabilityMental scoresSF-12Daily livingMonths post-ICU admissionMonths post-ICU dischargeMean MCS scoreMedical ICU survivorsPost-ICU admissionSF12 physical scoreProspective cohort studyMean PCS scoreTreatment of depressionCross-sectional associationsMean physical scoreSF-12 dataImpaired ADLICU admission
2007
The Association between Treatment Preferences and Trajectories of Care at the End-of-Life
Cosgriff JA, Pisani M, Bradley EH, O’Leary J, Fried TR. The Association between Treatment Preferences and Trajectories of Care at the End-of-Life. Journal Of General Internal Medicine 2007, 22: 1566-1571. PMID: 17874168, PMCID: PMC2219807, DOI: 10.1007/s11606-007-0362-6.Peer-Reviewed Original ResearchConceptsTreatment preferencesLife careIntensive treatmentAcute processAggressive careSymptomatic reliefTrajectories of endUnwanted aggressive careRelief of symptomsPatients' treatment preferencesDirection of patientsTrajectory of careHigh-quality endAdvanced diseaseSymptom controlConclusionsThe associationAssociations of preferenceIntensive interventionCarePatientsLife prolongationTreatmentPerson's ageReliefAssociation
2003
Underrecognition of Preexisting Cognitive Impairment by Physicians in Older ICU Patients
Pisani MA, Redlich C, McNicoll L, Ely EW, Inouye SK. Underrecognition of Preexisting Cognitive Impairment by Physicians in Older ICU Patients. CHEST Journal 2003, 124: 2267-2274. PMID: 14665510, DOI: 10.1378/chest.124.6.2267.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overAPACHECognition DisordersCritical CareCross-Sectional StudiesDiagnostic ErrorsFemaleGeriatricsHumansIntensive Care UnitsMalePrevalenceConceptsOlder ICU patientsCognitive impairmentICU patientsPhysician recognitionUrban university teaching hospitalCross-sectional comparative studyBlessed Dementia Rating ScalePreexisting Cognitive ImpairmentIndependent risk factorMedical record abstractionUniversity Teaching HospitalCognitive impairment increasesDementia Rating ScaleMajority of casesMedical ICUPatient factorsRecord abstractionICU physiciansIntensive carePhysician interviewsRisk factorsTeaching hospitalSerious illnessICUInformant Questionnaire