2015
Mortality among patients with pleural effusion undergoing thoracentesis
DeBiasi EM, Pisani MA, Murphy TE, Araujo K, Kookoolis A, Argento AC, Puchalski J. Mortality among patients with pleural effusion undergoing thoracentesis. European Respiratory Journal 2015, 46: 495-502. PMID: 25837039, PMCID: PMC4857137, DOI: 10.1183/09031936.00217114.Peer-Reviewed Original ResearchConceptsCongestive heart failurePleural effusionRenal failureHeart failureBenign etiologyMalignant effusionsHigh mortalityBilateral pleural effusionLong-term mortalityMortality of patientsProspective cohort studyMalignant pleural effusionBaseline characteristicsChart reviewCohort studyNonmalignant effusionsPoor prognosisHigh riskPatientsEffusionStandardised criteriaThoracentesisMortalityEtiologyFailurePatient-Centered Outcomes Following Thoracentesis
Argento AC, Murphy TE, Pisani MA, Araujo KL, Puchalski J. Patient-Centered Outcomes Following Thoracentesis. PLEURA 2015, 2: 237399751560040. PMID: 26767192, PMCID: PMC4708257, DOI: 10.1177/2373997515600404.Peer-Reviewed Original ResearchPleural interventionsSustained improvementPleural effusionProspective observational cohort studyTertiary care academic medical centerAdditional pleural proceduresObservational cohort studyMajority of patientsShort Form-12Multivariable logistic regressionPatient-centered outcomesAcademic medical centerSignificant clinical impactAdult patientsCohort studyHepatic hydrothoraxSecondary outcomesDays postprocedureInfectious etiologyPrimary outcomeTherapeutic thoracentesisAnalytical cohortForm-12Significant morbidityIndex procedure
2014
Mortality of Hospitalized Patients with Pleural Effusions
Kookoolis AS, Puchalski JT, Murphy TE, Araujo KL, Pisani MA. Mortality of Hospitalized Patients with Pleural Effusions. Journal Of Pulmonary & Respiratory Medicine 2014, 4: 184. PMID: 25977841, PMCID: PMC4428160, DOI: 10.4172/2161-105x.1000184.Peer-Reviewed Original ResearchSeverity of illnessShort-term survival benefitPleural effusionSurvival benefitPulmonary diseaseYale-New Haven HospitalTerm survival benefitMedical servicesCause mortalityHazard ratioHospital admissionHospitalized patientsMedical patientsMalignant effusionsMedical recordsMedical populationsProtective effectHigh riskPatientsEffusionThoracentesesLarger studyMortalityIllnessOne-year
2013
The Safety of Thoracentesis in Patients with Uncorrected Bleeding Risk
Puchalski JT, Argento AC, Murphy TE, Araujo KL, Pisani MA. The Safety of Thoracentesis in Patients with Uncorrected Bleeding Risk. Annals Of The American Thoracic Society 2013, 10: 336-341. PMID: 23952852, PMCID: PMC3960907, DOI: 10.1513/annalsats.201210-088oc.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnticoagulantsBlood Coagulation DisordersClopidogrelCohort StudiesDrainageFemaleHepatic InsufficiencyHumansInternational Normalized RatioMaleMiddle AgedPlatelet Aggregation InhibitorsPleural EffusionPostoperative HemorrhageProspective StudiesRenal Insufficiency, ChronicRisk FactorsThrombocytopeniaTiclopidineWarfarinConceptsBleeding riskHematocrit levelsProspective observational cohort studySafety of thoracentesisWithholding of medicationsObservational cohort studyPotential bleeding riskElevated INRCohort studyRenal diseaseCommon etiologyPleural effusionRisk factorsObservational studyPatientsThoracentesisMedicationsHemothoraxTransfusionSignificant differencesRiskDiseasePhysiological factorsPhysiological parametersSafety