1998
Hydromorphone–Naloxone Combinations in Opioid-Dependent Humans Under a Naloxone Novel-Response Discrimination Procedure
Oliveto A, Rosen M, Kosten T, Hameedi F, Woods S, Kosten T. Hydromorphone–Naloxone Combinations in Opioid-Dependent Humans Under a Naloxone Novel-Response Discrimination Procedure. Experimental And Clinical Psychopharmacology 1998, 6: 169-178. PMID: 9608349, DOI: 10.1037/1064-1297.6.2.169.Peer-Reviewed Original ResearchConceptsNaloxone-appropriate respondingNovel-appropriate respondingDose-related increaseNovel-response drug discrimination procedureOpioid-dependent humansDose-related decreaseDrug discrimination procedureHuman laboratory modelOpioid withdrawalDiscrimination procedureNaloxoneHydromorphoneNonhuman dataAppropriate respondingRespondingPlaceboMethadone
1997
Dose Dependent Effects of Yohimbine on Methadone Maintained Patients
Hameedi F, Woods S, Rosen M, Pearsall H, Kosten T. Dose Dependent Effects of Yohimbine on Methadone Maintained Patients. The American Journal Of Drug And Alcohol Abuse 1997, 23: 327-333. PMID: 9143642, DOI: 10.3109/00952999709040950.Peer-Reviewed Original Research
1995
Opiate Dependence and Withdrawal: Preliminary Assessment Using Single Photon Emission Computerized Tomography (SPECT)
Krystal J, Woods S, Kosten T, Rosen M, Seibyl J, Van Dyck C, Price L, Zubal I, Hoffer P, Charney D. Opiate Dependence and Withdrawal: Preliminary Assessment Using Single Photon Emission Computerized Tomography (SPECT). The American Journal Of Drug And Alcohol Abuse 1995, 21: 47-63. PMID: 7762544, DOI: 10.3109/00952999509095229.Peer-Reviewed Original ResearchConceptsRegional brain functionOpiate withdrawal signsSingle Photon Emission Computerized TomographyHealthy subjectsNaloxone administrationOpiate withdrawalOpiate dependenceBrain functionParietal cortexHexamethylpropyleneamine oximeWithdrawal signsNaloxone effectChronic opiate dependencePlacebo-controlled studyRegional alterationsComparison of patientsMethadone-maintained patientsRegional cerebral perfusionPhoton Emission Computerized TomographyOpiate-dependent patientsRight temporal cortexRight parietal cortexFunctional brain imaging technologiesSingle photon emissionEmission computerized tomographyReliability of Sequential Naloxone Challenge Tests
Rosen M, McMahon T, Margolin A, Gill T, Woods S, Pearsall H, Kreek M, Kosten T. Reliability of Sequential Naloxone Challenge Tests. The American Journal Of Drug And Alcohol Abuse 1995, 21: 453-467. PMID: 8561097, DOI: 10.3109/00952999509002710.Peer-Reviewed Original Research
1992
Use of cocaine to prevent opiate withdrawal
Rosen M, Wallace E, Sullivan M, Stine S, Kosten T. Use of cocaine to prevent opiate withdrawal. American Journal Of Psychiatry 1992, 149: 1609b-1609. PMID: 1415835, DOI: 10.1176/ajp.149.11.1609b.Peer-Reviewed Original ResearchCocaine-Associated Panic Attacks in Methadone-Maintained Patients
Rosen M, Kosten T. Cocaine-Associated Panic Attacks in Methadone-Maintained Patients. The American Journal Of Drug And Alcohol Abuse 1992, 18: 57-62. PMID: 1314016, DOI: 10.3109/00952999209001611.Peer-Reviewed Original Research
1991
Buprenorphine: Beyond Methadone?
Rosen M, Kosten T. Buprenorphine: Beyond Methadone? Psychiatric Services 1991, 42: 347-349. PMID: 2050347, DOI: 10.1176/ps.42.4.347.Peer-Reviewed Original ResearchConceptsConnecticut Mental Health CenterHuman immunodeficiency virusPromising new treatmentMental health centersSubstance abuse treatmentDepartment of PsychiatryAbuse of cocaineIntravenous heroinImmunodeficiency virusHealth centersYale University SchoolNew treatmentsAbuse treatmentGuest authorsDrug addictsDr. RosenUniversity SchoolRisk-taking behaviorTreatmentMethadoneResearch UnitHeroinCocaine