1996
Effect of clonidine pretreatment on naloxone-precipitated opiate withdrawal.
Rosen M, McMahon T, Hameedi F, Pearsall H, Woods S, Kreek M, Kosten T. Effect of clonidine pretreatment on naloxone-precipitated opiate withdrawal. Journal Of Pharmacology And Experimental Therapeutics 1996, 276: 1128-35. PMID: 8786543.Peer-Reviewed Original ResearchMeSH KeywordsAdrenocorticotropic HormoneAdultBlood PressureBody TemperatureClonidineDose-Response Relationship, DrugFemaleHumansHydrocortisoneMaleNaloxoneSubstance Withdrawal SyndromeConceptsClonidine pretreatmentOpiate withdrawalAdrenocorticotropic hormone (ACTH) responseDiastolic blood pressureNaloxone-precipitated opiate withdrawalNaloxone challenge testHeroin-dependent subjectsMeasures of withdrawalNasal congestionBlood pressureNew medicationsWithdrawal severityTesting medicationsChallenge testPlasma cortisolHormone responseConsecutive daysPilot studyClonidineMedicationsPositive controlWithdrawalBase linePretreatmentTwo-factor analysis
1995
Reliability of Sequential Naloxone Challenge Tests
Rosen M, McMahon T, Margolin A, Gill T, Woods S, Pearsall H, Kreek M, Kosten T. Reliability of Sequential Naloxone Challenge Tests. The American Journal Of Drug And Alcohol Abuse 1995, 21: 453-467. PMID: 8561097, DOI: 10.3109/00952999509002710.Peer-Reviewed Original Research