2019
Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures
Datta R, Wang T, Zhu M, Dembry LM, Han L, Allore H, Quagliarello V, Juthani-Mehta M. Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures. Infection Control And Hospital Epidemiology 2019, 40: 470-472. PMID: 30821230, PMCID: PMC6482377, DOI: 10.1017/ice.2019.22.Peer-Reviewed Original ResearchConceptsUrinary tract infectionIncidence rate ratiosAdvanced cancer patientsAsymptomatic bacteriuriaCancer patientsAntimicrobial therapySymptomatic urinary tract infectionPotential urinary tract infectionTract infectionsInappropriate therapyAntimicrobial daysComfort measuresBacteriuriaCandiduriaCFU/mLPatientsTherapyRate ratioMLInfection
2016
Effect of Cranberry Capsules on Bacteriuria Plus Pyuria Among Older Women in Nursing Homes: A Randomized Clinical Trial
Juthani-Mehta M, Van Ness PH, Bianco L, Rink A, Rubeck S, Ginter S, Argraves S, Charpentier P, Acampora D, Trentalange M, Quagliarello V, Peduzzi P. Effect of Cranberry Capsules on Bacteriuria Plus Pyuria Among Older Women in Nursing Homes: A Randomized Clinical Trial. JAMA 2016, 316: 1879-1887. PMID: 27787564, PMCID: PMC5300771, DOI: 10.1001/jama.2016.16141.Peer-Reviewed Original ResearchConceptsUrinary tract infectionPresence of bacteriuriaSymptomatic urinary tract infectionCranberry capsulesNursing homesOlder womenTreatment groupsControl groupPlacebo-controlled efficacy trialSignificant differencesRate of deathAntibiotic-resistant organismsControl group participantsCause deathStudy surveillanceCause hospitalizationSecondary outcomesTract infectionsPrimary outcomeOverall adherenceAntimicrobial utilizationClinical trialsEfficacy trialsPyuriaUnadjusted results
2014
Urinary Tract Infections in Older Women: A Clinical Review
Mody L, Juthani-Mehta M. Urinary Tract Infections in Older Women: A Clinical Review. JAMA 2014, 311: 844-854. PMID: 24570248, PMCID: PMC4194886, DOI: 10.1001/jama.2014.303.Peer-Reviewed Original ResearchConceptsSymptomatic urinary tract infectionRecurrent urinary tract infectionsUrinary tract infectionAsymptomatic bacteriuriaOlder womenTract infectionsUrine cultureRecurrent symptomatic urinary tract infectionsDiagnosis of UTIOlder community-dwelling womenEnglish-language human studiesChronic suppressive antibioticsCostovertebral angle painNegative dipstick resultsSymptomatic UTI episodesVaginal estrogen therapyAdverse effect profilePositive urine cultureLocal resistance ratesCommunity-dwelling womenLow pretest probabilityCareful clinical evaluationClinical diagnostic criteriaSearch of OvidRecent sexual intercourse
2013
Diagnosis and Management of Urinary Tract Infection in Older Adults
Rowe TA, Juthani-Mehta M. Diagnosis and Management of Urinary Tract Infection in Older Adults. Infectious Disease Clinics Of North America 2013, 28: 75-89. PMID: 24484576, PMCID: PMC4079031, DOI: 10.1016/j.idc.2013.10.004.Peer-Reviewed Original ResearchUrinary tract infection in older adults
Rowe TA, Juthani-Mehta M. Urinary tract infection in older adults. Aging Health 2013, 9: 519-528. PMID: 24391677, PMCID: PMC3878051, DOI: 10.2217/ahe.13.38.Peer-Reviewed Original ResearchUrinary tract infectionTract infectionsAsymptomatic bacteriuriaOlder adultsSymptomatic urinary tract infectionLong-term care facilitiesMultidrug-resistant organismsEvidence-based approachGenitourinary symptomsGold standard definitionConsensus guidelinesDiagnostic challengeCare facilitiesInfectionBacteriuriaDiagnostic accuracyYoung adultsDiagnosisAdultsCliniciansFuture studiesStandard definitionSignificant problemSymptomsPrevalence