2020
Pragmatic approach to neuraxial anesthesia in obstetric patients with disorders of the vertebral column, spinal cord and neuromuscular system
Walsh E, Zhang Y, Madden H, Lehrich J, Leffert L. Pragmatic approach to neuraxial anesthesia in obstetric patients with disorders of the vertebral column, spinal cord and neuromuscular system. Regional Anesthesia & Pain Medicine 2020, 46: 258-267. PMID: 33115718, DOI: 10.1136/rapm-2020-101792.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesia, ObstetricalAnesthesia, ObstetricalAnesthesia, SpinalCesarean SectionFemaleHumansPregnancyRetrospective StudiesSpinal CordSpineConceptsNeuraxial anesthesiaObstetric patientsSpinal cordCesarean delivery anesthesiaCesarean deliveryLabor analgesiaNeuraxial analgesiaVertebral columnCase seriesGeneral anesthesiaObstetrical patientsRetrospective studyDelivery anesthesiaPatient injuryAnesthesiaPatient harmPatientsNarrative reviewAvailable evidenceUnwarranted fearsNeuromuscular systemAdditional riskPresent unique challengesAnalgesiaCord
2019
Lumbar neuraxial procedures in thrombocytopenic patients across populations: A systematic review and meta-analysis
Bauer ME, Toledano RD, Houle T, Beilin Y, MacEachern M, McCabe M, Rector D, Cooper JP, Gernsheimer T, Landau R, Leffert L. Lumbar neuraxial procedures in thrombocytopenic patients across populations: A systematic review and meta-analysis. Journal Of Clinical Anesthesia 2019, 61: 109666. PMID: 31810860, DOI: 10.1016/j.jclinane.2019.109666.Peer-Reviewed Original ResearchMeSH KeywordsAnesthesia, EpiduralAnesthesia, SpinalHematoma, Epidural, SpinalHumansPlatelet CountSpinal PunctureDon’t throw the baby out with the bathwater: spinal-epidural hematoma in the setting of obstetric thromboprophylaxis and neuraxial anesthesia
Leffert L, Horlocker T, Landau R. Don’t throw the baby out with the bathwater: spinal-epidural hematoma in the setting of obstetric thromboprophylaxis and neuraxial anesthesia. International Journal Of Obstetric Anesthesia 2019, 39: 7-11. PMID: 31202587, DOI: 10.1016/j.ijoa.2019.05.001.Peer-Reviewed Original Research
2014
Continuous measurement of cardiac output with the electrical velocimetry method in patients under spinal anesthesia for cesarean delivery
Liu Y, Pian-Smith MC, Leffert LR, Minehart RD, Torri A, Coté C, Kacmarek RM, Jiang Y. Continuous measurement of cardiac output with the electrical velocimetry method in patients under spinal anesthesia for cesarean delivery. Journal Of Clinical Monitoring And Computing 2014, 29: 627-634. PMID: 25510959, DOI: 10.1007/s10877-014-9645-8.Peer-Reviewed Original ResearchConceptsPre-defined time pointsElective cesarean deliveryCardiac outputCesarean deliverySpinal anesthesiaStroke volumeNon-invasive CO monitorContinuous CO monitoringSystemic vascular resistanceTime pointsMajority of patientsPeripheral venous pressureTreatment of hypotensionOnset of hypotensionCO monitoringVascular resistanceHemodynamic profileVenous pressureHemodynamic changesPatient's hemodynamicsPhenylephrine bolusPhenylephrine administrationPatient outcomesObservational studyPatient management
2013
Spinal Anesthesia in Severe Preeclampsia
Henke VG, Bateman BT, Leffert LR. Spinal Anesthesia in Severe Preeclampsia. Anesthesia & Analgesia 2013, 117: 686-693. PMID: 23868886, DOI: 10.1213/ane.0b013e31829eeef5.Peer-Reviewed Original ResearchConceptsSevere preeclampsiaSpinal anesthesiaIntraoperative hemodynamic managementSpinal-induced hypotensionHealthy parturientsAnesthetic optionsCesarean deliveryEpidural catheterHemodynamic managementNeuraxial anesthesiaEpidural anesthesiaHigh incidencePreeclampsiaAnesthesiaHypotensionSignificant differencesParturientsContraindicationsCatheterIncidence
2009
Clinical Implications of Neuraxial Anesthesia in the Parturient with Scoliosis
Ko JY, Leffert LR. Clinical Implications of Neuraxial Anesthesia in the Parturient with Scoliosis. Anesthesia & Analgesia 2009, 109: 1930-1934. PMID: 19923523, DOI: 10.1213/ane.0b013e3181bc3584.Peer-Reviewed Original Research
2008
Acute Reversible Stress-Induced Cardiomyopathy Associated with Cesarean Delivery under Spinal Anesthesia
Crimi E, Baggish A, Leffert L, Pian-Smith MC, Januzzi JL, Jiang Y. Acute Reversible Stress-Induced Cardiomyopathy Associated with Cesarean Delivery under Spinal Anesthesia. Circulation 2008, 117: 3052-3053. PMID: 18541755, DOI: 10.1161/circulationaha.107.744102.Peer-Reviewed Original Research