2018
The Role of the Anesthesiologist in Preventing Severe Maternal Morbidity and Mortality
McQUAID E, Leffert LR, Bateman BT. The Role of the Anesthesiologist in Preventing Severe Maternal Morbidity and Mortality. Clinical Obstetrics & Gynecology 2018, 61: 372-386. PMID: 29319586, DOI: 10.1097/grf.0000000000000350.Peer-Reviewed Original ResearchMeSH KeywordsAirway ManagementAnesthesia, EpiduralAnesthesia, GeneralAnesthesiologistsAnesthetics, LocalBlood TransfusionEchocardiographyEpidural AbscessFemaleHeadacheHematoma, Epidural, SpinalHumansIntubation, IntratrachealMaternal DeathMeningitisMonitoring, PhysiologicObstetric Labor ComplicationsPhysician's RolePregnancyPuerperal DisordersRespiratory AspirationRisk FactorsConceptsObstetric anesthesiologistSevere maternal morbidityLife-saving interventionsMaternal morbidityCesarean deliveryUnstable patientsGeneral anesthesiaObstetric suiteObstetric proceduresBedside managementClinical scenariosAnesthesiologistsIntensivistsAnesthesiaGreater experienceDeliveryAnalgesiaMorbidityPatientsUnique roleMortalityClinicians
2017
The incidence of pregnancy-related stroke: A systematic review and meta-analysis
Swartz RH, Cayley ML, Foley N, Ladhani NNN, Leffert L, Bushnell C, McClure J, Lindsay MP. The incidence of pregnancy-related stroke: A systematic review and meta-analysis. International Journal Of Stroke 2017, 12: 687-697. PMID: 28884652, DOI: 10.1177/1747493017723271.Peer-Reviewed Original ResearchMeSH KeywordsCanadaFemaleHumansIncidencePostpartum PeriodPregnancyPregnancy Complications, CardiovascularPuerperal DisordersRisk FactorsStrokeConceptsCerebral venous sinus thrombosisVenous sinus thrombosisPregnancy-related strokeSinus thrombosisStroke incidenceCrude rateSystematic reviewIncidence of strokeHigh-risk populationConclusions StrokePostpartum strokeNonhemorrhagic strokeIschemic strokePregnancy populationStroke riskPerinatal strokePooled analysisSubgroup analysisObstetrical careIncidence rateStroke typeOvid MEDLINEInclusion criteriaStroke ratePregnancy
2016
Risk of Pregnancy-Associated Stroke Across Age Groups in New York State
Miller EC, Gatollari HJ, Too G, Boehme AK, Leffert L, Elkind MS, Willey JZ. Risk of Pregnancy-Associated Stroke Across Age Groups in New York State. JAMA Neurology 2016, 73: 1461-1467. PMID: 27775757, DOI: 10.1001/jamaneurol.2016.3774.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsFemaleHumansIncidenceNew YorkPregnancyPregnancy Complications, CardiovascularPuerperal DisordersRiskStrokeYoung AdultConceptsPregnancy-associated strokePregnant/postpartum womenRisk of strokeIncidence risk ratioRisk factorsPostpartum womenAge groupsNonpregnant womenStroke riskOlder womenCumulative riskAge-specific incidence ratiosPost partumCalendar year 2003Cerebral venous thrombosisStroke risk factorsTransient ischemic attackVascular risk factorsOverall median ageLogistic regression modelsActive smokingChronic hypertensionIschemic attackNPAS groupCerebrovascular events
2015
Treatment patterns and short-term outcomes in ischemic stroke in pregnancy or postpartum period
Leffert LR, Clancy CR, Bateman BT, Cox M, Schulte PJ, Smith EE, Fonarow GC, Kuklina EV, George MG, Schwamm LH. Treatment patterns and short-term outcomes in ischemic stroke in pregnancy or postpartum period. American Journal Of Obstetrics And Gynecology 2015, 214: 723.e1-723.e11. PMID: 26709084, DOI: 10.1016/j.ajog.2015.12.016.Peer-Reviewed Original ResearchConceptsAcute stroke reperfusion therapyStroke reperfusion therapyShort-term outcomesTissue plasminogen activatorGuidelines-Stroke registryPregnancy-related strokeReperfusion therapyIschemic stroke patientsIschemic strokeNonpregnant womenPostpartum womenStroke patientsPlasminogen activatorPostpartum periodIntravenous tissue plasminogen activator useIntravenous tissue plasminogen activatorFavorable short-term outcomesTissue plasminogen activator useAcute reperfusion therapyCatheter-based thrombolysisGreater stroke severityMajor systemic bleedingNonpregnant women 18Symptomatic intracranial hemorrhageHistory of hypertension
2013
Epidemiology of Obstetric-Related ICU Admissions in Maryland
Wanderer JP, Leffert LR, Mhyre JM, Kuklina EV, Callaghan WM, Bateman BT. Epidemiology of Obstetric-Related ICU Admissions in Maryland. Critical Care Medicine 2013, 41: 1844-1852. PMID: 23648568, PMCID: PMC3716838, DOI: 10.1097/ccm.0b013e31828a3e24.Peer-Reviewed Original ResearchMeSH KeywordsAbortion, InducedAdolescentAdultAnesthesia, ObstetricalBlack PeopleCerebrovascular DisordersEmergency Service, HospitalFemaleHeart DiseasesHumansInfectionsIntensive Care UnitsLength of StayLiver FailureMarylandMaternal AgeMedicaidPatient AdmissionPatient TransferPregnancyPregnancy ComplicationsPregnancy, EctopicPuerperal DisordersPulmonary EmbolismRespiratory InsufficiencyUnited StatesWounds and InjuriesYoung AdultConceptsICU admissionPregnancy-related hypertensive diseaseRate of sepsisCritical care managementAppropriate International ClassificationClinical Modification codesTransfer of womenEctopic pregnancyAnesthetic complicationsHypertensive diseaseICU populationICU utilizationPostpartum patientsPulmonary embolismGenitourinary infectionsSevere morbidityCommon diagnosisCerebrovascular diseaseObstetric servicesPostpartum periodPostpartum conditionsCardiac diseaseInternational ClassificationAdmissionCare management