2022
The Society for Obstetric Anesthesia and Perinatology Coronavirus Disease 2019 Registry: An Analysis of Outcomes Among Pregnant Women Delivering During the Initial Severe Acute Respiratory Syndrome Coronavirus-2 Outbreak in the United States
Katz D, Bateman B, Kjaer K, Turner D, Spence N, Habib A, George R, Toledano R, Grant G, Madden H, Butwick A, Lynde G, Minehart R, Beilin Y, Houle T, Sharpe E, Kodali B, Bharadwaj S, Farber M, Palanisamy A, Prabhu M, Gonzales N, Landau R, Leffert L. The Society for Obstetric Anesthesia and Perinatology Coronavirus Disease 2019 Registry: An Analysis of Outcomes Among Pregnant Women Delivering During the Initial Severe Acute Respiratory Syndrome Coronavirus-2 Outbreak in the United States. Obstetric Anesthesia Digest 2022, 42: 27-28. DOI: 10.1097/01.aoa.0000816828.87126.61.Peer-Reviewed Original ResearchLow Molecular Weight Heparin, Unfractionated Heparin and Neuraxial Anaesthesia
Combs D, Leffert L. Low Molecular Weight Heparin, Unfractionated Heparin and Neuraxial Anaesthesia. 2022, 329-335. DOI: 10.1007/978-3-030-72487-0_49.Peer-Reviewed Original Research
2021
Pragmatic Approach to Neuraxial Anesthesia in Obstetric Patients With Disorders of the Vertebral Column, Spinal Cord, and Neuromuscular System
Walsh E, Zhang Y, Madden H, Lehrich J, Leffert L. Pragmatic Approach to Neuraxial Anesthesia in Obstetric Patients With Disorders of the Vertebral Column, Spinal Cord, and Neuromuscular System. Obstetric Anesthesia Digest 2021, 41: 164-165. DOI: 10.1097/01.aoa.0000796068.53863.3d.Peer-Reviewed Original Research
2020
Pragmatic approach to neuraxial anesthesia in obstetric patients with disorders of the vertebral column, spinal cord and neuromuscular system
Walsh E, Zhang Y, Madden H, Lehrich J, Leffert L. Pragmatic approach to neuraxial anesthesia in obstetric patients with disorders of the vertebral column, spinal cord and neuromuscular system. Regional Anesthesia & Pain Medicine 2020, 46: 258-267. PMID: 33115718, DOI: 10.1136/rapm-2020-101792.Peer-Reviewed Original ResearchConceptsNeuraxial anesthesiaObstetric patientsSpinal cordCesarean delivery anesthesiaCesarean deliveryLabor analgesiaNeuraxial analgesiaVertebral columnCase seriesGeneral anesthesiaObstetrical patientsRetrospective studyDelivery anesthesiaPatient injuryAnesthesiaPatient harmPatientsNarrative reviewAvailable evidenceUnwarranted fearsNeuromuscular systemAdditional riskPresent unique challengesAnalgesiaCordLumbar Neuraxial Procedures in Thrombocytopenic Patients Across Populations: A Systematic Review and Meta-analysis
Bauer M, Toledano R, Houle T, Beilin Y, MacEachern M, McCabe M, Rector D, Cooper J, Gernsheimer T, Landau R, Leffert L. Lumbar Neuraxial Procedures in Thrombocytopenic Patients Across Populations: A Systematic Review and Meta-analysis. Obstetric Anesthesia Digest 2020, 40: 118-118. DOI: 10.1097/01.aoa.0000693644.32975.42.Peer-Reviewed Original ResearchNeuraxial anesthetic proceduresSpinal epidural hematomaEpidural hematomaThrombocytopenic patientsNeuraxial proceduresAnesthetic proceduresSystematic reviewThreshold platelet countCesarean deliveryFetal factorsNeuraxial anesthesiaGeneral anesthesiaPlatelet countSide effectsMeta-AnalysisHematomaPatientsAnesthesiaReviewPopulation
2019
Don’t throw the baby out with the bathwater: spinal-epidural hematoma in the setting of obstetric thromboprophylaxis and neuraxial anesthesia
Leffert L, Horlocker T, Landau R. Don’t throw the baby out with the bathwater: spinal-epidural hematoma in the setting of obstetric thromboprophylaxis and neuraxial anesthesia. International Journal Of Obstetric Anesthesia 2019, 39: 7-11. PMID: 31202587, DOI: 10.1016/j.ijoa.2019.05.001.Peer-Reviewed Original ResearchRegional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-based Guidelines (Fourth Edition)
Horlocker T, Vandermeuelen E, Kopp S, Gogarten W, Leffert L, Benzon H. Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-based Guidelines (Fourth Edition). Obstetric Anesthesia Digest 2019, 39: 28-29. DOI: 10.1097/01.aoa.0000552901.03545.fb.Peer-Reviewed Original ResearchRegional anesthesiaFourth consensus conferenceVenous thromboembolism preventionEvidence-based guidelinesAmerican SocietyPatient safety issuesNeuraxial bleedingSpinal hematomaThromboembolism preventionAntithrombotic medicationSpinal anesthesiaCatastrophic complicationThrombolytic therapyObstetric anesthesiaPain medicineConsensus conferenceAnesthesiaConsensus documentEuropean SocietyHeightened riskRelevant literatureAnticoagulationSafety issuesBleedingHematoma
2018
The Role of the Anesthesiologist in Preventing Severe Maternal Morbidity and Mortality
McQUAID E, Leffert LR, Bateman BT. The Role of the Anesthesiologist in Preventing Severe Maternal Morbidity and Mortality. Clinical Obstetrics & Gynecology 2018, 61: 372-386. PMID: 29319586, DOI: 10.1097/grf.0000000000000350.Peer-Reviewed Original ResearchMeSH KeywordsAirway ManagementAnesthesia, EpiduralAnesthesia, GeneralAnesthesiologistsAnesthetics, LocalBlood TransfusionEchocardiographyEpidural AbscessFemaleHeadacheHematoma, Epidural, SpinalHumansIntubation, IntratrachealMaternal DeathMeningitisMonitoring, PhysiologicObstetric Labor ComplicationsPhysician's RolePregnancyPuerperal DisordersRespiratory AspirationRisk FactorsConceptsObstetric anesthesiologistSevere maternal morbidityLife-saving interventionsMaternal morbidityCesarean deliveryUnstable patientsGeneral anesthesiaObstetric suiteObstetric proceduresBedside managementClinical scenariosAnesthesiologistsIntensivistsAnesthesiaGreater experienceDeliveryAnalgesiaMorbidityPatientsUnique roleMortalityCliniciansNeuraxial Anesthesia in Obstetric Patients Receiving Thromboprophylaxis With Unfractionated or Low–Molecular-Weight Heparin
Leffert L, Dubois H, Butwick A, Carvalho B, Houle T, Landau R. Neuraxial Anesthesia in Obstetric Patients Receiving Thromboprophylaxis With Unfractionated or Low–Molecular-Weight Heparin. Obstetric Anesthesia Digest 2018, 38: 3-4. DOI: 10.1097/01.aoa.0000529964.63597.d5.Peer-Reviewed Original ResearchSpinal epidural hematomaObstetric patientsNeuraxial anesthesiaWeight heparinVenous thromboembolismCesarean deliveryEpidural hematomaPregnant womenNeuraxial blockadeNational guidelinesPatientsThromboprophylaxisHeparinAnesthesiaSafe useWomenLow-MolecularThromboembolismHematomaBlockadeReview reportsPresent review reports
2017
Integrating the New Thromboprophylaxis Guidelines Into Obstetric Anesthesia Practice
Leffert L, Landau R. Integrating the New Thromboprophylaxis Guidelines Into Obstetric Anesthesia Practice. Survey Of Anesthesiology 2017, 61: 14. DOI: 10.1097/01.sa.0000513496.39516.43.Peer-Reviewed Original ResearchVenous thromboembolismPatient care recommendationsObstetric anesthesia practiceConsensus BundleThromboprophylaxis guidelinesVTE ratesMaternal deathsNeuraxial anesthesiaObstetric patientsObstetric anesthesiaCare recommendationsAnesthesia practiceAnesthesiaNational PartnershipRiskThromboembolismPatients
2015
What’s new in obstetric anesthesia? Focus on preeclampsia
Leffert L. What’s new in obstetric anesthesia? Focus on preeclampsia. International Journal Of Obstetric Anesthesia 2015, 24: 264-271. PMID: 25936785, DOI: 10.1016/j.ijoa.2015.03.008.Peer-Reviewed Original ResearchConceptsMulti-organ systemsHigh-risk patientsPrevalence of preeclampsiaDefinition of preeclampsiaObstetric care teamPregnant patientsFetal effectsObstetric anesthesiaClinical managementCare teamPreeclampsiaTherapeutic interventionsPatientsContemporary dataRecent updatesComorbiditiesMorbidityPregnancyAnesthesiaPathogenesisEtiologyFetusesPrevalenceDiagnosisCare
2013
Spinal Anesthesia in Severe Preeclampsia
Henke VG, Bateman BT, Leffert LR. Spinal Anesthesia in Severe Preeclampsia. Anesthesia & Analgesia 2013, 117: 686-693. PMID: 23868886, DOI: 10.1213/ane.0b013e31829eeef5.Peer-Reviewed Original ResearchConceptsSevere preeclampsiaSpinal anesthesiaIntraoperative hemodynamic managementSpinal-induced hypotensionHealthy parturientsAnesthetic optionsCesarean deliveryEpidural catheterHemodynamic managementNeuraxial anesthesiaEpidural anesthesiaHigh incidencePreeclampsiaAnesthesiaHypotensionSignificant differencesParturientsContraindicationsCatheterIncidence
2011
Substance abuse and anesthesia
Graetz T, Leffert L. Substance abuse and anesthesia. 2011, 88-94. DOI: 10.1017/cbo9780511842306.016.Peer-Reviewed Original ResearchClinical practiceClinical topicsDaily clinical practiceNerve blockTransesophageal echocardiographyHarvard Medical School facultySubstance abuseRobotic surgeryAdvanced practitionersRecertification examsAnesthesiology departmentsAnesthesiaAnesthesia textbooksAcademic anesthesiology departmentsBoard reviewMedical school facultyEchocardiographySurgeryMallampatiObstetric hemorrhage
Gauran C, Leffert L. Obstetric hemorrhage. 2011, 757-760. DOI: 10.1017/cbo9780511842306.125.Peer-Reviewed Original ResearchClinical practiceClinical topicsDaily clinical practiceObstetric hemorrhageNerve blockTransesophageal echocardiographyHarvard Medical School facultyRobotic surgeryAdvanced practitionersRecertification examsAnesthesiology departmentsAnesthesia textbooksAcademic anesthesiology departmentsBoard reviewMedical school facultyEchocardiographyHemorrhageSurgeryAnesthesiaMallampatiPreeclampsia
Ortman A, Leffert L. Preeclampsia. 2011, 761-765. DOI: 10.1017/cbo9780511842306.126.Peer-Reviewed Original ResearchClinical practiceClinical topicsDaily clinical practiceNerve blockTransesophageal echocardiographyHarvard Medical School facultyRobotic surgeryAdvanced practitionersRecertification examsAnesthesiology departmentsAnesthesia textbooksAcademic anesthesiology departmentsBoard reviewMedical school facultyPreeclampsiaEchocardiographySurgeryAnesthesiaMallampati
2008
Acute Reversible Stress-Induced Cardiomyopathy Associated with Cesarean Delivery under Spinal Anesthesia
Crimi E, Baggish A, Leffert L, Pian-Smith MC, Januzzi JL, Jiang Y. Acute Reversible Stress-Induced Cardiomyopathy Associated with Cesarean Delivery under Spinal Anesthesia. Circulation 2008, 117: 3052-3053. PMID: 18541755, DOI: 10.1161/circulationaha.107.744102.Peer-Reviewed Original Research
2007
Preface
Pian-Smith M, Leffert L. Preface. 2007, xxi-xxii. DOI: 10.1017/cbo9780511586057.001.Peer-Reviewed Original Research
2006
Is Bilateral Cerebral Subdural Hematoma More Frequent after Epidural Anesthesia than Spinal Anesthesia?
Mashour G, Leffert L. Is Bilateral Cerebral Subdural Hematoma More Frequent after Epidural Anesthesia than Spinal Anesthesia? Anesthesiology 2006, 105: 1278. DOI: 10.1097/00000542-200612000-00033.Peer-Reviewed Original Research