Featured Publications
Are China’s oldest-old living longer with less disability? A longitudinal modeling analysis of birth cohorts born 10 years apart
Liu Z, Han L, Feng Q, Dupre ME, Gu D, Allore HG, Gill TM, Payne CF. Are China’s oldest-old living longer with less disability? A longitudinal modeling analysis of birth cohorts born 10 years apart. BMC Medicine 2019, 17: 23. PMID: 30704529, PMCID: PMC6357399, DOI: 10.1186/s12916-019-1259-z.Peer-Reviewed Original ResearchConceptsPartial life expectancyLess disabilityBirth cohortOldest old livingLife expectancyAge groupsHigher healthcare costsDisability-free life expectancySuccessive birth cohortsOldest-old individualsOctogenarian womenMultistate life tablesSubgroup analysisAge 80Healthcare costsRural residenceUrban-rural disparitiesOctogenariansCohortHealth inequalitiesPersonal assistanceDisability transitionsDisabilityNonagenariansSociodemographic heterogeneity
2022
Catastrophic health expenditure among Chinese adults living alone with cognitive impairment: findings from the CHARLS
Li C, Jin S, Cao X, Han L, Sun N, Allore H, Hoogendijk EO, Xu X, Feng Q, Liu X, Liu Z. Catastrophic health expenditure among Chinese adults living alone with cognitive impairment: findings from the CHARLS. BMC Geriatrics 2022, 22: 640. PMID: 35922775, PMCID: PMC9351200, DOI: 10.1186/s12877-022-03341-8.Peer-Reviewed Original ResearchTrends in the prevalence of vision impairment among the oldest-old Chinese population from 1998 to 2018.
Luo Y, Zhang Q, Han L, Shen Z, Chen Y, Wang K, Huang Z, De Fries CM, Cao G, Su H, Xu H, Chen Z, Ren Z, Hu Y, Xu B. Trends in the prevalence of vision impairment among the oldest-old Chinese population from 1998 to 2018. Journal Of Global Health 2022, 12: 11006. PMID: 35862489, DOI: 10.7189/jogh.12.11006.Peer-Reviewed Original ResearchConceptsOldest-old Chinese populationImpairment prevalenceVision impairmentChinese populationChronic conditionsHealth behaviorsHearing impairmentChinese Longitudinal Healthy Longevity SurveyProminent public health issueSociodemographic variablesRetrospective longitudinal studyPublic health issueLandolt C chartStudy entryChronic diseasesPrevalence trendsChinese adultsLongevity SurveyCognitive impairmentPrevalence changesPrevalenceUrban residenceOlder peopleHealth issuesImpairmentMultimorbidity measures differentially predicted mortality among older Chinese adults
Yao SS, Xu HW, Han L, Wang K, Cao GY, Li N, Luo Y, Chen YM, Su HX, Chen ZS, Huang ZT, Hu YH, Xu B. Multimorbidity measures differentially predicted mortality among older Chinese adults. Journal Of Clinical Epidemiology 2022, 146: 97-105. PMID: 35259446, DOI: 10.1016/j.jclinepi.2022.03.002.Peer-Reviewed Original ResearchConceptsNet reclassification indexIntegrated discrimination improvementMultimorbidity measuresMortality prediction modelOlder Chinese adultsMultimorbidity patternsC-statisticCondition countMortality predictionChinese adultsMultimorbidity trajectoriesNet reclassification improvementCox regressionReclassification improvementReclassification indexChronic conditionsDiscrimination improvementMortality riskHigh riskIntegrated discriminationMultimorbidityStudy designMortalityAdultsAgePatterns of cardiometabolic multimorbidity and the risk of depressive symptoms in a longitudinal cohort of middle-aged and older Chinese
Huang ZT, Luo Y, Han L, Wang K, Yao SS, Su HX, Chen S, Cao GY, De Fries CM, Chen ZS, Xu HW, Hu YH, Xu B. Patterns of cardiometabolic multimorbidity and the risk of depressive symptoms in a longitudinal cohort of middle-aged and older Chinese. Journal Of Affective Disorders 2022, 301: 1-7. PMID: 34999125, DOI: 10.1016/j.jad.2022.01.030.Peer-Reviewed Original ResearchConceptsCardiometabolic multimorbidityCardiometabolic diseasesHeart diseaseDepressive symptomsSelf-reported chronic conditionsEpidemiological Studies Depression ScaleAbsence of strokeRisk of depressionRetirement Longitudinal Study 2011Multiple cardiometabolic diseasesDose effectMental health preventionOlder ChineseAdditive effectChronic conditionsDisease combinationsLongitudinal cohortDepression ScaleHigh riskMultimorbidityPerson-centered healthcareDiabetesSymptomsHealth preventionChina Health
2021
Visual trajectories and risk of physical and cognitive impairment among older Chinese adults
Cao G, Wang K, Han L, Zhang Q, Yao S, Chen Z, Huang Z, Luo Y, Hu Y, Xu B. Visual trajectories and risk of physical and cognitive impairment among older Chinese adults. Journal Of The American Geriatrics Society 2021, 69: 2877-2887. PMID: 34111310, DOI: 10.1111/jgs.17311.Peer-Reviewed Original ResearchConceptsOlder Chinese adultsIADL disabilityCognitive impairmentChinese adultsADL disabilityFunctional impairmentCognitive functionMini-Mental State Examination scoreProgressive declineChinese Longitudinal Healthy Longevity SurveyState Examination scoreModerate declineGroup-based trajectory modelsKatz scaleLawton scalePotential confoundersLongevity SurveyImpairmentDecline trajectoriesChinese versionDisabilityLongitudinal studyAdultsRiskExamination scores
2020
Cognitive frailty in relation to adverse health outcomes independent of multimorbidity: results from the China health and retirement longitudinal study
Chen C, Park J, Wu C, Xue Q, Agogo G, Han L, Hoogendijk EO, Liu Z, Wu Z. Cognitive frailty in relation to adverse health outcomes independent of multimorbidity: results from the China health and retirement longitudinal study. Aging 2020, 12: 23129-23145. PMID: 33221750, PMCID: PMC7746379, DOI: 10.18632/aging.104078.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAge FactorsAgedAged, 80 and overChinaCognitionCognitive AgingCognitive DysfunctionDisability EvaluationFemaleFrail ElderlyFrailtyFunctional StatusHealth SurveysHospitalizationHumansLongitudinal StudiesMaleMiddle AgedMobility LimitationMultimorbidityPrognosisRetirementRisk AssessmentRisk FactorsConceptsCognitive frailtyInstrumental ADLPhysical frailtyHealth outcomesCognitive impairmentAdverse health outcomesRetirement Longitudinal StudyPhysical frailty assessmentChinese older adultsFrailty assessmentIADL disabilitySecondary preventionDaily livingHigh riskMobility disabilityMultimorbidityFrailtyChina HealthNormal cognitionBaseline cognitionHealthy agingOlder adultsDeathBasic activitiesHospitalizationVision impairment, vision correction, and cognitive decline among middle-aged and older Chinese: results from the China health and retirement longitudinal study
Cao GY, Yao SS, Wang K, Han L, Chen ZS, Huang ZT, Zhang Q, Wang C, Hu YH, Xu B. Vision impairment, vision correction, and cognitive decline among middle-aged and older Chinese: results from the China health and retirement longitudinal study. Aging & Mental Health 2020, 25: 2028-2035. PMID: 33063527, DOI: 10.1080/13607863.2020.1828271.Peer-Reviewed Original ResearchMultimorbidity among Two Million Adults in China
Wang X, Yao S, Wang M, Cao G, Chen Z, Huang Z, Wu Y, Han L, Xu B, Hu Y. Multimorbidity among Two Million Adults in China. International Journal Of Environmental Research And Public Health 2020, 17: 3395. PMID: 32414117, PMCID: PMC7277827, DOI: 10.3390/ijerph17103395.Peer-Reviewed Original ResearchConceptsIschemic heart diseaseCerebrovascular diseaseMultimorbidity patternsMultimorbidity prevalenceBeijing Medical Claim DataMedical claims dataMiddle-aged groupOlder Chinese individualsMillion adultsMorbidity treatmentOlder patientsRheumatoid arthritisPreventive careHeart diseaseChronic diseasesClaims dataHypertensionOlder groupOlder adultsStrong associationDiseaseCOPDMultimorbidityChinese individualsAppropriate guidelinesAssociations Between Somatic Multimorbidity Patterns and Depression in a Longitudinal Cohort of Middle-Aged and Older Chinese
Yao SS, Cao GY, Han L, Huang ZT, Chen ZS, Su HX, Hu Y, Xu B. Associations Between Somatic Multimorbidity Patterns and Depression in a Longitudinal Cohort of Middle-Aged and Older Chinese. Journal Of The American Medical Directors Association 2020, 21: 1282-1287.e2. PMID: 31928934, DOI: 10.1016/j.jamda.2019.11.028.Peer-Reviewed Original ResearchConceptsChronic somatic conditionsSomatic multimorbidityDepressive symptomsOlder Chinese adultsSomatic conditionsChinese adultsEpidemiological Studies Depression ScaleLongitudinal associationsRetirement Longitudinal Study 2011Multimorbidity patternsLongitudinal cohortDepression ScaleRespiratory conditionsHigh riskGreater oddsRespiratory patternMental disordersSymptomsChina HealthGreater riskOlder populationOlder adultsSkeletal patternClinical practitionersDepression
2019
Prevalence and Patterns of Multimorbidity in a Nationally Representative Sample of Older Chinese: Results From the China Health and Retirement Longitudinal Study
Yao SS, Cao GY, Han L, Chen ZS, Huang ZT, Gong P, Hu Y, Xu B. Prevalence and Patterns of Multimorbidity in a Nationally Representative Sample of Older Chinese: Results From the China Health and Retirement Longitudinal Study. The Journals Of Gerontology Series A 2019, 75: 1974-1980. PMID: 31406983, DOI: 10.1093/gerona/glz185.Peer-Reviewed Original ResearchConceptsPatterns of multimorbidityPrevalence of multimorbidityMultimorbidity patternsRetirement Longitudinal StudyOlder ChineseChina HealthPopulation-based studyDemographic characteristicsIndividual chronic diseasesLongitudinal studyCommon multimorbidity patternsLogistic regression modelsParticipants' demographic characteristicsNationally Representative SampleEntire cohortPotential confoundersChronic diseasesRepresentative sampleMultimorbidityAlcohol consumptionMemory-related diseasesUrban-rural differencesPrevalenceInterventional implicationsResidential region
2018
Disability Prior to Death Among the Oldest-Old in China
Liu Z, Han L, Wang X, Feng Q, Gill TM. Disability Prior to Death Among the Oldest-Old in China. The Journals Of Gerontology Series A 2018, 73: 1701-1707. PMID: 29408957, PMCID: PMC6230206, DOI: 10.1093/gerona/gly010.Peer-Reviewed Original Research
2013
Cardiovascular Disease and Hip Fracture among Older Inpatients in Beijing, China
Xu B, Han L, Liu H, Wang J, Bao XY, Xi HX, Zhao L, Yu GP. Cardiovascular Disease and Hip Fracture among Older Inpatients in Beijing, China. BioMed Research International 2013, 2013: 493696. PMID: 23936809, PMCID: PMC3713359, DOI: 10.1155/2013/493696.Peer-Reviewed Original ResearchConceptsHip fractureICD-10 codesCardiovascular diseaseHypertensive diseaseOlder inpatientsCerebrovascular diseaseHospitalization summary reportsOverall cardiovascular diseaseHip fracture patientsDiagnosis of CVDOccurrence rateChinese inpatientsFracture patientsCohort studyTertiary hospitalInpatientsDiseaseAssociationFracturesEuropean populationsComorbiditiesPatientsHospitalYearsDiagnosis