2020
Retinal Inputs to the Thalamus Are Selectively Gated by Arousal
Liang L, Fratzl A, Reggiani JDS, El Mansour O, Chen C, Andermann ML. Retinal Inputs to the Thalamus Are Selectively Gated by Arousal. Current Biology 2020, 30: 3923-3934.e9. PMID: 32795442, PMCID: PMC7665906, DOI: 10.1016/j.cub.2020.07.065.Peer-Reviewed Original ResearchConceptsVisual thalamusVisual responsesMajority of boutonsTwo-photon calciumCentral visual processingArousal stateIntermediate spatial frequenciesEnhancement of responsesAxonal boutonsRetinal axonsRetinal inputDifferent pupil sizesVisual pathwayThalamusBoutonsMouse thalamusVisual processingMagnitude of responseVisual information channelsDistinct subsetsEarly stagesPupil sizeNeural activityDifferential modulationBehavioral states
2018
A Fine-Scale Functional Logic to Convergence from Retina to Thalamus
Liang L, Fratzl A, Goldey G, Ramesh RN, Sugden AU, Morgan JL, Chen C, Andermann ML. A Fine-Scale Functional Logic to Convergence from Retina to Thalamus. Cell 2018, 173: 1343-1355.e24. PMID: 29856953, PMCID: PMC6003778, DOI: 10.1016/j.cell.2018.04.041.Peer-Reviewed Original ResearchConceptsAxonal boutonsRetinal ganglion cellsTwo-photon calciumImage-forming visionClusters of boutonsVisual thalamusGanglion cellsRetinal axonsBouton clustersThalamusMouse thalamusIndividual axonsDifferent axonsFeature selectivityBoutonsFine-scale organizationAxonsDendritic domainsUltrastructural analysisRetina
2010
The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing, and Mosaic Analysis
Potter CJ, Tasic B, Russler EV, Liang L, Luo L. The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing, and Mosaic Analysis. Cell 2010, 141: 536-548. PMID: 20434990, PMCID: PMC2883883, DOI: 10.1016/j.cell.2010.02.025.Peer-Reviewed Original ResearchConceptsMARCM analysisQa gene clusterCell division patternsBinary expression systemTransgene expression patternsTransgene expressionGAL4 systemGene functionMosaic analysisGene clusterRegulatory genesMammalian cellsCell divisionDivision patternsLow basal expressionLineage tracingExpression systemExpression patternsNeuronal lineageOlfactory attractionCell growthBasal expressionDrosophilaRepressionExpression