1990
T-cell-directed hepatocyte damage in autoimmune chronic active hepatitis
Wen L, Peakman M, Lobo-Yeo A, Vergani D, Mowat A, Mieli-Vergani, McFarlane B. T-cell-directed hepatocyte damage in autoimmune chronic active hepatitis. The Lancet 1990, 336: 1527-1530. PMID: 1979365, DOI: 10.1016/0140-6736(90)93306-a.Peer-Reviewed Original ResearchConceptsAutoimmune chronic active hepatitisChronic active hepatitisActive hepatitisPeripheral bloodT lymphocytesAutologous B lymphocytesLiver membrane antigensT cell clonesAsialoglycoprotein receptorActivated T lymphocytesLiver cell membraneSpecific autoantibodiesAutoimmune attackImmune attackHepatocyte damageHepatitisB lymphocytesLymphocytesBloodLipoprotein complexAutoantibodiesPatientsCell membraneAntigenClones
1989
LIVER MEMBRANE-SPECIFIC T CEL CLONES IN AUTOIMMUNE CHRONIC ACTIVE HEPATITIS (aCAH)
Wen L, Lobo Yeo A, Pcakman M, Mowat A, Mieli Vargant G, Vargani D. LIVER MEMBRANE-SPECIFIC T CEL CLONES IN AUTOIMMUNE CHRONIC ACTIVE HEPATITIS (aCAH). Pediatric Research 1989, 26: 272-272. DOI: 10.1203/00006450-198909000-00050.Peer-Reviewed Original ResearchPeripheral blood mononuclear cellsAllogeneic peripheral blood mononuclear cellsT cell clonesIL-2Cell clonesIrradiated autologous peripheral blood mononuclear cellsAutologous peripheral blood mononuclear cellsExcess IL-2Blood mononuclear cellsAntigen presenting cellsInterleukin-2 receptorLiver cell membraneAnti-IL2RAUTOIMMUNE CHRONICAnti-CD4HLA-DRMononuclear cellsImmune attackPresenting cellsT cellsT lymphocytesPatientsRabbit kidney membranesCells/Liver membranes