2001
Presynaptic target of Ca2+ action on neuropeptide and acetylcholine release in Aplysia californica
Ohnuma K, Whim M, Fetter R, Kaczmarek L, Zucker R. Presynaptic target of Ca2+ action on neuropeptide and acetylcholine release in Aplysia californica. The Journal Of Physiology 2001, 535: 647-662. PMID: 11559764, PMCID: PMC2278817, DOI: 10.1111/j.1469-7793.2001.00647.x.Peer-Reviewed Original ResearchConceptsSensory neuronsCholinergic synapsesPeptidergic synapsesAcetylcholine releasePostsynaptic responsesAction potentialsMost synaptic contactsIntracellular calcium concentrationPeptidergic vesiclesSingle action potentialAplysia californicaDose-response curveDense-core vesiclesNeuron B2Neuron B3Cholinergic transmissionSynaptic contactsLinear dose-response curvePostsynaptic neuronsPresynaptic neuronsCholinergic releasePresynaptic targetCholinergic vesiclesReleasable poolPatch pipette
1998
Heterologous Expression of the Kv3.1 Potassium Channel Eliminates Spike Broadening and the Induction of a Depolarizing Afterpotential in the Peptidergic Bag Cell Neurons
Whim M, Kaczmarek L. Heterologous Expression of the Kv3.1 Potassium Channel Eliminates Spike Broadening and the Induction of a Depolarizing Afterpotential in the Peptidergic Bag Cell Neurons. Journal Of Neuroscience 1998, 18: 9171-9180. PMID: 9801357, PMCID: PMC6792887, DOI: 10.1523/jneurosci.18-22-09171.1998.Peer-Reviewed Original ResearchConceptsBag cell neuronsCell neuronsAction potentialsCalcium entryUse-dependent inactivationExpression of Kv3.1Kv3.1 potassium channelPeptidergic bag cell neuronsControl neuronsSpontaneous firingBrief synaptic stimulationCalcium currentNeuronal excitabilityIntracellular calciumCalcium influxSynaptic stimulationDepolarizing afterpotentialsBAPTA-AMAfterpotentialsNeuronsPotassium channelsClusters of cellsKv3.1InductionPhysiological role