1991
Dexamethasone increases potassium channel messenger RNA and activity in clonal pituitary cells.
Levitan E, Hemmick L, Birnberg N, Kaczmarek L. Dexamethasone increases potassium channel messenger RNA and activity in clonal pituitary cells. Endocrinology 1991, 5: 1903-8. PMID: 1791837, DOI: 10.1210/mend-5-12-1903.Peer-Reviewed Original ResearchConceptsPituitary cellsChannel expressionClonal rat pituitary cellsChannel messenger RNAIon channel expressionRat pituitary cellsDose-dependent mannerClonal pituitary cellsAnterior pituitaryLong-term effectsRat hypothalamusSimilar pharmacologyGlucocorticoid agonistGlucocorticoid hormonesChannel mRNAGH3 cellsElectrical activitySecretionSteady-state concentrationsTerm effectsPituitaryExcitable cellsHormoneIon channelsMessenger RNA
1990
Transfection of activated ras into an excitable cell line (AtT-20) alters tetrodotoxin sensitivity of voltage-dependent sodium current
Flamm R, Birnberg N, Kaczmarek L. Transfection of activated ras into an excitable cell line (AtT-20) alters tetrodotoxin sensitivity of voltage-dependent sodium current. Pflügers Archiv - European Journal Of Physiology 1990, 416: 120-125. PMID: 2191273, DOI: 10.1007/bf00370232.Peer-Reviewed Original ResearchConceptsTTX-sensitive currentsResistant currentSodium currentTTX-resistant sodium currentsVoltage-dependent sodium currentsSodium channel blocker tetrodotoxinTTX-resistant currentChannel blocker tetrodotoxinAnterior pituitary tumorsVoltage-dependent sodiumCell linesC-Ha-ras geneTTX-sensitiveBlocker tetrodotoxinPituitary tumorsExcitable cell lineC-Ha-ras oncogeneTetrodotoxin sensitivityTetrodotoxinAtT-20 cellsControl cellsCellsRate of inactivationTransfectionTumors