2019
Loss of NaV1.2-Dependent Backpropagating Action Potentials in Dendrites Contributes to Autism and Intellectual Disability
Kaczmarek LK. Loss of NaV1.2-Dependent Backpropagating Action Potentials in Dendrites Contributes to Autism and Intellectual Disability. Neuron 2019, 103: 551-553. PMID: 31437449, DOI: 10.1016/j.neuron.2019.07.032.Peer-Reviewed Original Research
2010
Fragile X Mental Retardation Protein Is Required for Rapid Experience-Dependent Regulation of the Potassium Channel Kv3.1b
Strumbos JG, Brown MR, Kronengold J, Polley DB, Kaczmarek LK. Fragile X Mental Retardation Protein Is Required for Rapid Experience-Dependent Regulation of the Potassium Channel Kv3.1b. Journal Of Neuroscience 2010, 30: 10263-10271. PMID: 20685971, PMCID: PMC3485078, DOI: 10.1523/jneurosci.1125-10.2010.Peer-Reviewed Original ResearchConceptsMental retardation proteinAnterior ventral cochlear nucleusFragile X Mental Retardation ProteinRNA-binding proteinProtein translationFMRPWild-type animalsSpecific mRNAsSound localization circuitVentral cochlear nucleusBrainstem synaptosomesExperience-dependent regulationProtein levelsAmplitude-modulated stimuliProteinTrapezoid bodyCochlear nucleusMale miceMedial nucleusNeuronal activityPotassium currentWT controlsSynaptic plasticityTonotopic axisAcoustic stimulation
2001
Formation, Maintenance, and Plasticity of Chemical Synapses
B.Levitan I, Kaczmarek L. Formation, Maintenance, and Plasticity of Chemical Synapses. 2001, 467-506. DOI: 10.1093/oso/9780195145236.003.0018.Peer-Reviewed Original ResearchNervous systemSynaptic connectionsFormation of synapsesAdult nervous systemSpecific synaptic connectionsImmature neuronsSynaptic contactsAdult neuronsMature neuronsElectrical stimulationSynaptic plasticityNeuronal formBrain functionChemical synapsesNeuronsElectrical activityNeurite elongationSynaptogenesisSynapsesProperties of cells