1992
Expression of the H-ras oncogene induces potassium conductance and neuron-specific potassium channel mRNAs in the AtT20 cell line
Hemmick L, Perney T, Flamm R, Kaczmarek L, Birnberg N. Expression of the H-ras oncogene induces potassium conductance and neuron-specific potassium channel mRNAs in the AtT20 cell line. Journal Of Neuroscience 1992, 12: 2007-2014. PMID: 1607925, PMCID: PMC6575920, DOI: 10.1523/jneurosci.12-06-02007.1992.Peer-Reviewed Original ResearchConceptsRas-transfected cellsAtT20 cell lineAtT20 cellsEJ-ras oncogeneCell linesPotassium channelsVoltage-dependent potassium channelsRas proteinsPituitary-derived cellsMRNA speciesPlasma membraneSpliced productsPotassium channel mRNASame geneChannel mRNADifferential expressionPotassium currentExcitable cellsVoltage-dependent potassium currentsTwo- to threefold increaseMRNAOncogeneSpeciesExpressionPhenotype
1990
Estrogen induction of a small, putative K+ channel mRNA in rat uterus
Pragnell M, Snay K, Trimmer J, MacLusky N, Naftolin F, Kaczmarek L, Boyle M. Estrogen induction of a small, putative K+ channel mRNA in rat uterus. Neuron 1990, 4: 807-812. PMID: 2344412, DOI: 10.1016/0896-6273(90)90207-v.Peer-Reviewed Original ResearchConceptsMRNA speciesAmino acid proteinProkaryotic ion channelsDramatic long-term changesMolecular cloningAcid proteinIon channel expressionMammalian sourcesIon channelsXenopus oocytesVoltage-dependent channelsSpeciesStructural motifsCritical roleChannel expressionMRNAChannel mRNAEstrogen inductionLong-term changesInductionCloningProteinMotifRegulationOocytes