2024
Sex Differences in the Blood Metabolome During Acute Response to Ischemic Stroke
Dylla L, Higgins H, Stephenson D, Reisz J, Vu T, Poisson S, Herson P, Monte A. Sex Differences in the Blood Metabolome During Acute Response to Ischemic Stroke. Journal Of Women's Health 2024, 33: 1378-1384. PMID: 38946610, DOI: 10.1089/jwh.2023.1133.Peer-Reviewed Original ResearchIschemic strokeLinear regression modelsMass spectrometry-based metabolomicsLifetime risk of strokeAssociated with neurological outcomeDifferentially expressed metabolitesRegression modelsAcute ischemic strokeRisk of strokeComprehensive stroke centerBlood metabolomeNeurological outcomeAcute treatmentMetabolomic profilesLifetime riskNeurological functionIndividual metabolitesTherapeutic potentialStroke centersAcute responseResults:</i></b>Study objectiveMetabolomicsStrokeNIHSSIdentification of specific recommendations for prehospital stroke care associated with shorter door-to-CT times – An analysis of Get with the Guidelines-Stroke registry and prehospital data
Dylla L, Higgins H, Wham C, Leppert M, Ravare B, Jeppson K, Bina H, Monte A, Poisson S. Identification of specific recommendations for prehospital stroke care associated with shorter door-to-CT times – An analysis of Get with the Guidelines-Stroke registry and prehospital data. Frontiers In Stroke 2024, 3: 1355889. DOI: 10.3389/fstro.2024.1355889.Peer-Reviewed Original ResearchDoor-to-CT timeAmerican Heart AssociationGuidelines-Stroke registryAmerican Heart Association recommendationsPrehospital careStroke patientsEmergency medical services documentationIschemic stroke patientsDoor-to-computed tomographyCare of stroke patientsPrehospital medical recordsPrehospital Stroke ScaleCare of strokeMultivariate linear regression modelPrehospital providersPrehospital dataProvider educationStroke signsPotential confoundersLinear regression modelsTreatment of acute strokeComprehensive stroke centerDescriptive statisticsSuspected strokeMedical records
2023
Abstract TP47: Impact Of Prehospital Care And Patient Presentation On In-hospital Treatment Of Acute Ischemic Stroke
DYLLA L, Higgins H, Ravare B, Jeppson K, Bina H, Rice J, Herson P, Monte A, Poisson S. Abstract TP47: Impact Of Prehospital Care And Patient Presentation On In-hospital Treatment Of Acute Ischemic Stroke. Stroke 2023, 54: atp47-atp47. DOI: 10.1161/str.54.suppl_1.tp47.Peer-Reviewed Original ResearchEmergency medicine servicesDoor-to-CT timeAmerican Heart AssociationLinear regression modelsDoor-to-computed tomographyIn-hospital quality of careQuality-of-care metricsGuideline concordant careQuality of careAcute stroke careDoor-to-CTIn-hospital careRegression modelsMultivariate linear regression modelConcordant careProvider compliancePrehospital careStroke careStroke guidelinesIschemic stroke patientsMedicine serviceStroke symptomsIn-hospital outcomesComprehensive stroke centerAcute ischemic stroke patients
2020
Retrospective analysis of the hemodynamic consequences of prehospital supplemental oxygen in acute stroke
Dylla L, Cushman J, Abar B, Benesch C, Jones C, O'Banion M, Adler D. Retrospective analysis of the hemodynamic consequences of prehospital supplemental oxygen in acute stroke. The American Journal Of Emergency Medicine 2020, 38: 2125-2129. PMID: 33069547, PMCID: PMC7704903, DOI: 10.1016/j.ajem.2020.07.021.Peer-Reviewed Original ResearchConceptsMean arterial pressureCerebral blood flowHemodynamic profileSupplemental oxygenRetrospective analysisHemodynamic consequencesOxygen saturationPrehospital oxygen saturationAcute strokePeripheral vascular resistanceLevels of supplemental oxygenAcademic comprehensive stroke centerSubjects' medical records.Comprehensive stroke centerClinical characteristicsAcute stroke patientsVascular resistanceArterial pressureMultivariate linear regressionMultivariate analysisImprove stroke outcomesMedical recordsGuidelines-Stroke registryPenumbral tissueBlood flow
2019
Prehospital supplemental oxygen for acute stroke – A retrospective analysis
Dylla L, Adler D, Abar B, Benesch C, Jones C, O'Banion M, Cushman J. Prehospital supplemental oxygen for acute stroke – A retrospective analysis. The American Journal Of Emergency Medicine 2019, 38: 2324-2328. PMID: 31787444, PMCID: PMC7231670, DOI: 10.1016/j.ajem.2019.11.002.Peer-Reviewed Original ResearchConceptsRespiratory complicationsNeurological outcomeSupplemental oxygenRetrospective analysisRate of respiratory complicationsPrehospital oxygen saturationAdministration of supplemental oxygenAssociated with neurological outcomeMultivariate logistic regressionAcademic comprehensive stroke centerSubjects' medical records.Comprehensive stroke centerClinical characteristicsRespiratory compromiseAcute stroke patientsRetrospective natureEligible patientsNo significant increaseImprove stroke outcomesMedical recordsGuidelines-Stroke registryOxygen saturationPenumbral tissuePotential confoundersControl):