2008
Cross-sensitivity of skin rashes with antiepileptic drug use
Hirsch LJ, Arif H, Nahm EA, Buchsbaum R, Resor SR, Bazil CW. Cross-sensitivity of skin rashes with antiepileptic drug use. Neurology 2008, 71: 1527-1534. PMID: 18981374, DOI: 10.1212/01.wnl.0000334295.50403.4c.Peer-Reviewed Original ResearchConceptsRate of rashAntiepileptic drugsValproic acidSpecific antiepileptic drugsAntiepileptic drug useMore antiepileptic drugsCertain antiepileptic drugsAED selectionSkin rashIndividual patientsRashPatientsLamotrigineOxcarbazepineDrug usePhenytoinCarbamazepineLevetiracetamZonisamideGabapentinTiagabineVigabatrinClobazamDrugsMedications
2006
Lamotrigine and its applications in the treatment of epilepsy and other neurological and psychiatric disorders
Malik S, Arif H, Hirsch LJ. Lamotrigine and its applications in the treatment of epilepsy and other neurological and psychiatric disorders. Expert Review Of Neurotherapeutics 2006, 6: 1609-1627. PMID: 17144777, DOI: 10.1586/14737175.6.11.1609.Peer-Reviewed Original ResearchConceptsBroad-spectrum antiepileptic drugBipolar disorder type ILennox-Gastaut syndromeTreatment of epilepsySerious skin rashesTreatment of womenFavorable pharmacokinetic propertiesConcomitant medicationsNeuropathic painElderly patientsSkin rashAdjunctive treatmentDose adjustmentGeneralized seizuresPartial seizuresAntiepileptic drugsSlow titrationNeurological conditionsPsychiatric disordersAdult populationLamotriginePharmacokinetic propertiesSmall riskPreliminary dataEpilepsy