2015
Enteric‐coated mycophenolate sodium given in combination with tacrolimus has a lower incidence of serious infections in Asian renal‐transplant recipients compared with mycophenolate mofetil
Feng J, Zhang L, Zhao P, Bow L, Tian J. Enteric‐coated mycophenolate sodium given in combination with tacrolimus has a lower incidence of serious infections in Asian renal‐transplant recipients compared with mycophenolate mofetil. International Journal Of Clinical Practice Supplement 2015, 69: 1-7. PMID: 26176848, DOI: 10.1111/ijcp.12660.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdultChinaDose-Response Relationship, DrugEnzyme InhibitorsFemaleFollow-Up StudiesGraft RejectionHumansImmunosuppressive AgentsIncidenceKidney TransplantationMaleMiddle AgedMycophenolic AcidProspective StudiesSurgical Wound InfectionTablets, Enteric-CoatedTacrolimusTransplant RecipientsConceptsAsian renal transplant recipientsRenal transplant recipientsEnteric-coated mycophenolate sodiumEC-MPSMycophenolate sodiumMMF groupIncidence of infectionMycophenolate mofetilSerious infectionsAdverse eventsLower incidenceTherapeutic effectLive donor kidney transplant recipientsInfection rateGastro-intestinal adverse eventsClinical trial registration numberIncidence of biopsyPosttransplant infection ratesTimes of diarrheaKidney transplant recipientsSerum creatinine levelsTRIAL REGISTRATION NUMBEREnteric-coated formulationAcute rejectionRenal transplantation
1997
Localized delivery of heparin to angioplasty sites with iontophoresis
Mitchel J, Azrin M, Fram D, Bow L, McKay R. Localized delivery of heparin to angioplasty sites with iontophoresis. Catheterization And Cardiovascular Interventions 1997, 41: 315-323. PMID: 9213031, DOI: 10.1002/(sici)1097-0304(199707)41:3<315::aid-ccd13>3.0.co;2-m.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, BalloonAngioplasty, Balloon, CoronaryAnimalsAnticoagulantsAortaCoronary VesselsDose-Response Relationship, DrugDrug Delivery SystemsElastic TissueEquipment DesignHeparinIontophoresisMaleMuscle, Smooth, VascularPlatelet AggregationRatsRats, Sprague-DawleySwineTunica IntimaTunica MediaConceptsPorcine coronary arteriesBalloon injuryPlatelet depositionDrug depositionCoronary arteryIontophoretic catheterHeparin deliveryControl vesselsLocal deliveryContralateral control vesselsIontophoresis of salineEarly platelet depositionFluorescent heparinBalloon inflation pressureInternal elastic laminaIntramural localizationAngioplasty siteBalloon angioplastyCoronary studiesHemodynamic sequelaeIliac vesselsIntramural depositionImmediate drug deliveryPlatelet studiesArtery
1995
Activities of Clarithromycin, Azithromycin, and Ofioxacin in Combination with Liposomal or Unencapsulated Granulocyte-Macrophage Colony-Stimulating Factor against Intramacrophage Mycobacterium avium-Mycobacterium intracellulare
Onyeji C, Nightingale C, Tessier P, Nicolau D, Bow L. Activities of Clarithromycin, Azithromycin, and Ofioxacin in Combination with Liposomal or Unencapsulated Granulocyte-Macrophage Colony-Stimulating Factor against Intramacrophage Mycobacterium avium-Mycobacterium intracellulare. The Journal Of Infectious Diseases 1995, 172: 810-816. PMID: 7658075, DOI: 10.1093/infdis/172.3.810.Peer-Reviewed Original ResearchConceptsMycobacterium avium-Mycobacterium intracellulareGranulocyte-macrophage colony-stimulating factorColony-stimulating factorGM-CSFHuman macrophage infection modelMaximal killing effectTherapeutic peak concentrationsTherapeutic trough concentrationsActivity of clarithromycinEffects of ofloxacinMacrophage infection modelMAI infectionTrough concentrationsSerum troughUseful adjunctClarithromycinAzithromycinInfection modelPeak levelsSignificant augmentationKilling effectPeak concentrationOfloxacinAntimycobacterial activityIntracellulare