Featured Publications
Development and validation of a prediction model for persistent functional impairment among older ICU survivors
Ferrante LE, Murphy TE, Leo‐Summers L, O'Leary JR, Vander Wyk B, Pisani MA, Gill TM. Development and validation of a prediction model for persistent functional impairment among older ICU survivors. Journal Of The American Geriatrics Society 2022, 71: 188-197. PMID: 36196998, PMCID: PMC9870848, DOI: 10.1111/jgs.18075.Peer-Reviewed Original ResearchConceptsPersistent functional impairmentICU hospitalizationFunctional impairmentValidation cohortICU admissionDevelopment cohortOlder Intensive Care Unit SurvivorsIntensive care unit survivorsOlder adultsOlder ICU survivorsMonths of dischargeHigh-risk survivorsCommunity-living participantsGood calibrationHospital lengthICU survivorsCritical illnessMedian agePrior hospitalizationFunctional recoveryNational HealthProbable dementiaHospitalizationHigh riskDepressive symptomsSociety of Critical Care Medicine's International Consensus Conference on Prediction and Identification of Long-Term Impairments After Critical Illness.
Mikkelsen ME, Still M, Anderson BJ, Bienvenu OJ, Brodsky MB, Brummel N, Butcher B, Clay AS, Felt H, Ferrante LE, Haines KJ, Harhay MO, Hope AA, Hopkins RO, Hosey M, Hough CTL, Jackson JC, Johnson A, Khan B, Lone NI, MacTavish P, McPeake J, Montgomery-Yates A, Needham DM, Netzer G, Schorr C, Skidmore B, Stollings JL, Umberger R, Andrews A, Iwashyna TJ, Sevin CM. Society of Critical Care Medicine's International Consensus Conference on Prediction and Identification of Long-Term Impairments After Critical Illness. Critical Care Medicine 2020, 48: 1670-1679. PMID: 32947467, DOI: 10.1097/ccm.0000000000004586.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsActivities of Daily LivingCognitive DysfunctionCritical CareCritical IllnessHumansSurvivorsConceptsCritical illnessLong-term impairmentInternational Consensus ConferenceHospital dischargeSerial assessmentConsensus conferenceFunctional abilityCritical Care Medicine Consensus ConferenceSystematic reviewPost-intensive care syndromeCare coordination strategiesMontreal Cognitive Assessment (MoCA) testHigh-risk patientsHealth-related qualityMental health functionCognitive Assessment testOriginal systematic reviewAssessment of survivorsEvent Scale-RevisedICU admissionEuroQol-5DCochrane LibraryHospital AnxietyDepression ScaleLife measuresThe Combined Effects of Frailty and Cognitive Impairment on Post-ICU Disability among Older ICU Survivors
Ferrante LE, Murphy TE, Leo-Summers LS, Gahbauer EA, Pisani MA, Gill TM. The Combined Effects of Frailty and Cognitive Impairment on Post-ICU Disability among Older ICU Survivors. American Journal Of Respiratory And Critical Care Medicine 2019, 200: 107-110. PMID: 30883191, PMCID: PMC6603056, DOI: 10.1164/rccm.201806-1144le.Peer-Reviewed Original ResearchFactors Associated with Functional Recovery among Older Intensive Care Unit Survivors
Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM. Factors Associated with Functional Recovery among Older Intensive Care Unit Survivors. American Journal Of Respiratory And Critical Care Medicine 2016, 194: 299-307. PMID: 26840348, PMCID: PMC4970594, DOI: 10.1164/rccm.201506-1256oc.Peer-Reviewed Original ResearchConceptsHigher body mass indexOlder ICU survivorsIntensive care unitBody mass indexFunctional recoveryICU survivorsICU admissionMass indexOlder Intensive Care Unit SurvivorsIntensive care unit survivorsOlder adultsPoor functional recoveryCritical illnessIndependent predictorsCare unitMultivariable analysisFunctional outcomePremorbid functionPotential predictorsVision impairmentAdmissionSurvivorsAnalytic sampleFunctional activityMonths
2022
Long-term recovery after critical illness in older adults
Kaushik R, Ferrante LE. Long-term recovery after critical illness in older adults. Current Opinion In Critical Care 2022, 28: 572-580. PMID: 35950731, PMCID: PMC9458622, DOI: 10.1097/mcc.0000000000000981.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOlder ICU patientsPost-ICU recoveryCritical illnessGeriatric syndromesLong-term recoveryOlder adultsICU patientsRisk factorsIncidence of frailtyOlder ICU survivorsTransitional care programLong-term outcomesContinuum of careSocial isolationRecent epidemiologic workSocial risk factorsICU survivorsRecent literature pertainingUnique needsRecent longitudinal studiesNew disabilityWorse outcomesFunctional declineCare programSyndrome
2020
Prediction Models for Physical, Cognitive, and Mental Health Impairments After Critical Illness: A Systematic Review and Critical Appraisal
Haines KJ, Hibbert E, McPeake J, Anderson BJ, Bienvenu OJ, Andrews A, Brummel NE, Ferrante LE, Hopkins RO, Hough CL, Jackson J, Mikkelsen ME, Leggett N, Montgomery-Yates A, Needham DM, Sevin CM, Skidmore B, Still M, van Smeden M, Collins GS, Harhay MO. Prediction Models for Physical, Cognitive, and Mental Health Impairments After Critical Illness: A Systematic Review and Critical Appraisal. Critical Care Medicine 2020, 48: 1871-1880. PMID: 33060502, PMCID: PMC7673641, DOI: 10.1097/ccm.0000000000004659.Peer-Reviewed Original ResearchConceptsCritical illnessMental health impairmentSystematic reviewHealth impairmentBias assessment toolRisk of biasStudy eligibility criteriaPrediction model RiskComposite outcomeAdult patientsTrial enrollmentCochrane LibraryPatient recoveryIndependent reviewersHigh riskEligibility criteriaOutcome measurementsStandardized outcomesAdult survivorsStudy characteristicsIllnessStudy designSystematic searchImpairmentCandidate predictors
2019
Patient-Centered Outcomes in Critical Illness: Will My Patient Be Functionally and Cognitively Intact?
Geer JH, Qi W, Ferrante LE. Patient-Centered Outcomes in Critical Illness: Will My Patient Be Functionally and Cognitively Intact? Seminars In Respiratory And Critical Care Medicine 2019, 40: 638-647. PMID: 31826264, DOI: 10.1055/s-0039-1698379.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements