2021
Ovarian transplantation with robotic surgery and a neovascularizing human extracellular matrix scaffold: a case series in comparison to meta-analytic data
Oktay K, Marin L, Bedoschi G, Pacheco F, Sugishita Y, Kawahara T, Taylan E, Acosta C, Bang H. Ovarian transplantation with robotic surgery and a neovascularizing human extracellular matrix scaffold: a case series in comparison to meta-analytic data. Fertility And Sterility 2021, 117: 181-192. PMID: 34801235, PMCID: PMC8863399, DOI: 10.1016/j.fertnstert.2021.08.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCohort StudiesCryopreservationExtracellular MatrixFemaleFertility PreservationHumansMeta-Analysis as TopicNeovascularization, PhysiologicOvaryPregnancyPregnancy RateRetrospective StudiesRobotic Surgical ProceduresTissue Culture TechniquesTissue ScaffoldsTransplantation, AutologousYoung AdultConceptsGraft longevityCase seriesOvarian functionLow-dose aspirinOvarian tissue transplantationOvarian cortical piecesLower embryo qualityOocytes/embryosNeonatal outcomesTransdermal estrogenChemotherapy exposureOvarian transplantationCortical piecesMeta-analytic dataLower abdomenHealthy childrenLive birthsMAIN OUTCOMEGraft vascularizationExtracellular matrix scaffoldsOvarian tissueAneuploidy rateFunction returnsEmbryo qualityMeta-analytic updateComparison of open and a novel closed vitrification system with slow freezing for human ovarian tissue cryopreservation
Sugishita Y, Taylan E, Kawahara T, Shahmurzada B, Suzuki N, Oktay K. Comparison of open and a novel closed vitrification system with slow freezing for human ovarian tissue cryopreservation. Journal Of Assisted Reproduction And Genetics 2021, 38: 2723-2733. PMID: 34398400, PMCID: PMC8581089, DOI: 10.1007/s10815-021-02297-9.Peer-Reviewed Original ResearchConceptsFollicle survivalCortical piecesPrimary folliclesHuman ovarian tissue cryopreservationOvarian tissue cryopreservationCell death pathway activationOvarian cortical piecesPrimordial follicle survivalPrimordial follicle densityHuman ovarian tissueClosed vitrification systemTissue cryopreservationDNA damageOvarian tissueHistological analysisPathway activationApoptosis rateDevice groupSlow freezing
2018
Ovarian tissue cryopreservation and transplantation
Bedoschi G, Oktay K. Ovarian tissue cryopreservation and transplantation. 2018, 148-152. DOI: 10.1201/9781351141680-19.Peer-Reviewed Original ResearchOvarian tissue cryopreservationOvarian cortical piecesFertility preservationAdvanced treatment strategiesOvarian transplantationCortical piecesOvarian stimulationSurvival outcomesOvarian functionTreatment strategiesTissue cryopreservationAccelerated phaseEarly detectionHeterotopic ovarian transplantationFertility preservation proceduresLower abdominal wallFirst descriptionOvarian endocrineInitial ischemiaOvarian cryopreservationPharmacological supportTransplant proceduresFollicle lossCancer careCancer patients
2015
Ovarian Tissue Cryopreservation: Where Are We Now?
Bedoschi G, Oktay K. Ovarian Tissue Cryopreservation: Where Are We Now? 2015, 71-78. DOI: 10.1007/978-3-319-17849-3_6.Peer-Reviewed Original ResearchFertility preservationOvarian stimulationOvarian cortical piecesAdvanced treatment strategiesPre-pubertal childrenOvarian cryopreservationCortical piecesSurvival outcomesOvarian functionCancer careCancer patientsTreatment strategiesEndocrine functionOocyte cryopreservationAccelerated phaseEarly detectionCancer communityPatientsTransplantationFirst descriptionStimulationSufficient time periodChemotherapySuccessful restorationCancer
2004
Embryo Development After Heterotopic Transplantation of Cryopreserved Ovarian Tissue
Oktay K, Buyuk E, Veeck L, Zaninovic N, Xu K, Takeuchi T, Opsahl M, Rosenwaks Z. Embryo Development After Heterotopic Transplantation of Cryopreserved Ovarian Tissue. Obstetrical & Gynecological Survey 2004, 59: 520-522. DOI: 10.1097/00006254-200407000-00018.Peer-Reviewed Original ResearchOvarian cortical piecesOvarian stimulationCortical piecesOvarian tissueOvarian functionEndocrine functionFollicle-stimulating hormone increaseFrozen-thawed ovarian tissueSequelae of chemotherapyHuman menopausal gonadotropinFollicle-stimulating hormoneOvarian endocrine functionLower abdominal wallRecombinant human chorionic gonadotropinHuman chorionic gonadotropinIntracytoplasmic sperm injectionGonadotoxic chemotherapyMenopausal gonadotropinMost patientsOocyte retrievalOvarian transplantationPremature menopauseOocyte maturityPatient's uterusAbstract Patients