Impact of adjuvant chemotherapy or tamoxifen-alone on the ovarian reserve of young women with breast cancer
Goldfarb S, Turan V, Bedoschi G, Taylan E, Abdo N, Cigler T, Bang H, Patil S, Dickler M, Oktay K. Impact of adjuvant chemotherapy or tamoxifen-alone on the ovarian reserve of young women with breast cancer. Breast Cancer Research And Treatment 2020, 185: 165-173. PMID: 32930927, PMCID: PMC7877450, DOI: 10.1007/s10549-020-05933-7.Peer-Reviewed Original ResearchConceptsAnti-Mullerian hormoneOvarian reserveAdjuvant chemotherapyBreast cancerAMH levelsChemotherapy regimensCompletion of ACSerum AMH levelsAdjuvant tamoxifenAMH recoveryChemotherapy groupPrimary diagnosisBaseline ageMethodsOne hundredAMH assessmentRegimensChemotherapyYoung womenTamoxifenSignificant recoveryCancerMixed effects modelsMonthsTreatment effectsWomenImpact of breast cancer chemotherapy on ovarian damage and recovery.
Goldfarb S, Bedoschi G, Turan V, Crown A, Abdo N, Dickler M, Oktay K. Impact of breast cancer chemotherapy on ovarian damage and recovery. Journal Of Clinical Oncology 2020, 38: e24059-e24059. DOI: 10.1200/jco.2020.38.15_suppl.e24059.Peer-Reviewed Original ResearchAMH recoveryBreast cancerBaseline AMHOvarian reserveNon-metastatic breast cancerBaseline AMH levelsTime of diagnosisBreast cancer patientsBreast cancer chemotherapyImpact of chemoImportant predictorCancer ptsChemo groupGonadotoxic chemoChemotherapy regimenOvarian damageSerum AMHAMH levelsStudy entryTamoxifen treatmentFertility preservationLow AMHProspective studyCancer patientsFuture fertility