2011
Cation permeation through connexin 43 hemichannels is cooperative, competitive and saturable with parameters depending on the permeant species
Orellana J, Díaz E, Schalper K, Vargas A, Bennett M, Sáez J. Cation permeation through connexin 43 hemichannels is cooperative, competitive and saturable with parameters depending on the permeant species. Biochemical And Biophysical Research Communications 2011, 409: 603-609. PMID: 21600880, PMCID: PMC3118918, DOI: 10.1016/j.bbrc.2011.05.031.Peer-Reviewed Original Research
2010
Connexin 43 hemichannels mediate the Ca2+ influx induced by extracellular alkalinization
Schalper KA, Sánchez HA, Lee SC, Altenberg GA, Nathanson MH, Sáez JC. Connexin 43 hemichannels mediate the Ca2+ influx induced by extracellular alkalinization. American Journal Of Physiology - Cell Physiology 2010, 299: c1504-c1515. PMID: 20881238, PMCID: PMC3774097, DOI: 10.1152/ajpcell.00015.2010.Peer-Reviewed Original Research
2008
Connexin Hemichannel Composition Determines the FGF-1–induced Membrane Permeability and Free [Ca2+]i Responses
Schalper K, Palacios-Prado N, Retamal M, Shoji K, Martínez A, Sáez J. Connexin Hemichannel Composition Determines the FGF-1–induced Membrane Permeability and Free [Ca2+]i Responses. Molecular Biology Of The Cell 2008, 19: 3501-3513. PMID: 18495870, PMCID: PMC2488314, DOI: 10.1091/mbc.e07-12-1240.Peer-Reviewed Original ResearchConceptsHeLa cellsC-terminusP38 MAP kinase-dependent pathwayMembrane permeabilityMAP kinase-dependent pathwayDifferent connexin typesKinase-dependent pathwayFGF-1HeLa transfectantsDiverse cellsRegulatory sitesCellular responsesCell surfaceCell permeabilizationHemichannelsConnexin typesSerum-free mediumCx26CellsPossible roleCell densityCx43Early intracellularPermeabilizationTransfectants
2007
Possible Involvement of Different Connexin43 Domains in Plasma Membrane Permeabilization Induced by Ischemia-Reperfusion
Retamal MA, Schalper KA, Shoji KF, Orellana JA, Bennett MV, Sáez JC. Possible Involvement of Different Connexin43 Domains in Plasma Membrane Permeabilization Induced by Ischemia-Reperfusion. The Journal Of Membrane Biology 2007, 218: 49-63. PMID: 17705051, DOI: 10.1007/s00232-007-9043-y.Peer-Reviewed Original ResearchOpening of connexin 43 hemichannels is increased by lowering intracellular redox potential
Retamal MA, Schalper KA, Shoji KF, Bennett MV, Sáez JC. Opening of connexin 43 hemichannels is increased by lowering intracellular redox potential. Proceedings Of The National Academy Of Sciences Of The United States Of America 2007, 104: 8322-8327. PMID: 17494739, PMCID: PMC1895948, DOI: 10.1073/pnas.0702456104.Peer-Reviewed Original Research