2021
Polysomnographic Phenotypes of Obstructive Sleep Apnea and Incident Type 2 Diabetes: Results from the DREAM Study.
Ding Q, Qin L, Wojeck B, Inzucchi SE, Ibrahim A, Bravata DM, Strohl KP, Yaggi HK, Zinchuk AV. Polysomnographic Phenotypes of Obstructive Sleep Apnea and Incident Type 2 Diabetes: Results from the DREAM Study. Annals Of The American Thoracic Society 2021, 18: 2067-2078. PMID: 34185617, PMCID: PMC8641817, DOI: 10.1513/annalsats.202012-1556oc.Peer-Reviewed Original ResearchMeSH KeywordsDiabetes Mellitus, Type 2HumansMalePhenotypePolysomnographySeverity of Illness IndexSleep Apnea, ObstructiveConceptsApnea-hypopnea indexObstructive sleep apneaPolysomnographic phenotypeIncident T2DMRisk of T2DMPredictive valueSleep apneaBlood glucoseRisk factorsCardiovascular diseaseMild obstructive sleep apneaIncident type 2 diabetesMultivariable-adjusted regression modelsCox proportional hazards regressionNew physician diagnosisT2DM risk predictionIncident cardiovascular diseaseIncident type 2Body mass indexProportional hazards regressionT2DM risk factorsBehavioral risk factorsType 2 diabetesMale veteran populationRisk regression models
2009
Obstructive Sleep Apnea as a Risk Factor for Type 2 Diabetes
Botros N, Concato J, Mohsenin V, Selim B, Doctor K, Yaggi HK. Obstructive Sleep Apnea as a Risk Factor for Type 2 Diabetes. The American Journal Of Medicine 2009, 122: 1122-1127. PMID: 19958890, PMCID: PMC2799991, DOI: 10.1016/j.amjmed.2009.04.026.Peer-Reviewed Original ResearchConceptsMore severe sleep apneaPositive airway pressure useSevere sleep apneaObstructive sleep apneaRisk of diabetesSleep apneaRisk factorsIncident diabetesMAIN OUTCOMEPositive airway pressure therapyType 2 diabetes mellitusVeterans Affairs Connecticut Healthcare SystemAirway pressure therapyObservational cohort studyApnea-hypopnea indexSleep-disordered breathingBody mass indexCross-sectional studyCohort studyDiagnostic polysomnogramGlucose intoleranceConsecutive patientsDiabetes mellitusMass indexPhysician diagnosis