2020
The effect of anticoagulation on outcomes after liver and spleen injuries: A research consortium of New England centers for trauma (ReCONECT) study
Bhattacharya B, Askari R, Davis KA, Dorfman J, Eid AI, Elsharkawy AE, Kasotakis G, Mackey S, Odom S, Okafor BU, Rosenblatt M, Ruditsky A, Velmahos G, Maung AA. The effect of anticoagulation on outcomes after liver and spleen injuries: A research consortium of New England centers for trauma (ReCONECT) study. Injury 2020, 51: 1994-1998. PMID: 32482426, DOI: 10.1016/j.injury.2020.05.002.Peer-Reviewed Original ResearchMeSH KeywordsAnticoagulantsHumansInjury Severity ScoreLiverMiddle AgedNew EnglandRetrospective StudiesSpleenTrauma CentersWounds, NonpenetratingConceptsNon-ACS patientsEffect of anticoagulationNon-operative managementSpleen injurySplenic injuryLiver injuryInitial non-operative managementSignificant differencesUse of anticoagulationBlood product transfusionMulticenter retrospective studyAC drugsMore PRBCsInjury gradeProduct transfusionCommon indicationAC patientsAtrial fibrillationRetrospective studyAnticoagulationSolid organsPatientsInjuryStudy periodLiver
2018
Opioid dependency is independently associated with inferior clinical outcomes after trauma
Hsiang WR, McGeoch C, Lee S, Cheung W, Becher R, Davis KA, Schuster K. Opioid dependency is independently associated with inferior clinical outcomes after trauma. Injury 2018, 50: 192-196. PMID: 30342762, DOI: 10.1016/j.injury.2018.10.015.Peer-Reviewed Original ResearchConceptsNon-home dischargeOpioid-dependent patientsLength of stayInjury Severity ScoreOpioid dependencyVentilator daysMajor complicationsClinical outcomesPrescription abuseIllicit abuseLonger LOSChronic pain subgroupsMore ventilator daysOpioid-naïve patientsUse of opioidsAcademic Level IHigher readmission ratesInferior clinical outcomesChronic pain patientsOpioid subgroupsNaïve patientsAdult patientsPain subgroupsPatient demographicsReadmission ratesInsurance Status Biases Trauma-system Utilization and Appropriate Interfacility Transfer
Zogg CK, Schuster KM, Maung AA, Davis KA. Insurance Status Biases Trauma-system Utilization and Appropriate Interfacility Transfer. Annals Of Surgery 2018, 268: 681-689. PMID: 30004929, DOI: 10.1097/sla.0000000000002954.Peer-Reviewed Original ResearchConceptsNTC patientsMajor injuriesOlder adult trauma patientsNationwide Emergency Department SampleOptimal trauma careAdult trauma patientsEmergency department admissionsEmergency Department SampleTrauma center careTransfer of patientsComplex traumatic injuriesMultilevel logistic regressionTrauma patientsDepartment admissionsHigh morbidityTC careDirect admissionInsurance statusInterfacility transferUninsured patientsTrauma careTraumatic injuryOutcome measuresTrauma systemCenter care
2017
Natural history of splenic vascular abnormalities after blunt injury
Zarzaur BL, Dunn JA, Leininger B, Lauerman M, Shanmuganathan K, Kaups K, Zamary K, Hartwell JL, Bhakta A, Myers J, Gordy S, Todd SR, Claridge JA, Teicher E, Sperry J, Privette A, Allawi A, Burlew CC, Maung AA, Davis KA, Cogbill T, Bonne S, Livingston DH, Coimbra R, Kozar RA. Natural history of splenic vascular abnormalities after blunt injury. Journal Of Trauma And Acute Care Surgery 2017, 83: 999-1005. PMID: 28570347, DOI: 10.1097/ta.0000000000001597.Peer-Reviewed Original ResearchConceptsBlunt splenic injurySplenic vascular injuryVascular injuryVascular abnormalitiesSplenic injuryTomography scanNatural historyRisks of splenectomyOutcomes of patientsComputed tomography scanNonoperative failureAdult patientsBlunt injuryEarly splenectomyUnderwent splenectomyInjury characteristicsMultivariable analysisTrauma centerTrauma radiologistSplenectomyHigh riskPrognostic studiesPatientsAppropriate managementLevel III
2016
Trauma patients on new oral anticoagulation agents have lower mortality than those on warfarin
Maung AA, Bhattacharya B, Schuster KM, Davis KA. Trauma patients on new oral anticoagulation agents have lower mortality than those on warfarin. Journal Of Trauma And Acute Care Surgery 2016, 81: 652-657. PMID: 27438683, DOI: 10.1097/ta.0000000000001189.Peer-Reviewed Original ResearchConceptsNew oral agentsNew oral anticoagulation agentsOral anticoagulation agentsAnticoagulation agentsControl groupLevel 1 trauma center databaseLower mortalityTrauma-related mortalityInjury Severity ScoreMechanism of injuryIntensive care unitMultivariable logistic regressionHigher overall mortalityTrauma center databaseTraumatic brain injuryElectronic medical recordsWarfarin groupHospital courseOral agentsControl patientsIndependent predictorsOverall mortalityTrauma patientsCare unitRetrospective reviewThe older they are the harder they fall: Injury patterns and outcomes by age after ground level falls
Bhattacharya B, Maung A, Schuster K, Davis KA. The older they are the harder they fall: Injury patterns and outcomes by age after ground level falls. Injury 2016, 47: 1955-1959. PMID: 27346422, DOI: 10.1016/j.injury.2016.06.019.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsAgedAged, 80 and overAnticoagulantsAspirinComorbidityFemaleFollow-Up StudiesFractures, BoneGeriatric AssessmentHospitalizationHumansInjury Severity ScoreIntracranial HemorrhagesMaleMultiple TraumaPlatelet Aggregation InhibitorsRetrospective StudiesSurvival AnalysisTrauma CentersTreatment OutcomeUnited StatesConceptsGround-level fallInjury patternsAnticoagulation useAspirin useIntracranial bleedAnticoagulation agentsAbdominal solid organ injuriesCertain injury patternsAdult trauma patientsSolid organ injuryAntiplatelet useHome dischargePatient characteristicsLife expectancy increasesMean ISSOrgan injuryOverall mortalityRetrospective reviewTrauma patientsGeriatric patientsSignificant morbidityTrauma centerPatient populationPelvic fracturesCervical spine
2015
ICD-9 diagnosis codes have poor sensitivity for identification of preexisting comorbidities in traumatic fracture patients
Samuel AM, Lukasiewicz AM, Webb ML, Bohl DD, Basques BA, Davis KA, Grauer JN. ICD-9 diagnosis codes have poor sensitivity for identification of preexisting comorbidities in traumatic fracture patients. Journal Of Trauma And Acute Care Surgery 2015, 79: 622-630. PMID: 26402537, DOI: 10.1097/ta.0000000000000805.Peer-Reviewed Original ResearchConceptsICD-9 diagnosis codesNational Trauma Data BankInjury Severity ScoreProximal tibia fracturesBilling codesTibia fracturesDiagnosis codesOdds ratioSurgeons National Trauma Data BankICD-9 billing codesTraumatic fracture patientsPrevious myocardial infarctionTrauma Data BankICD-9 diagnosisMultivariate logistic regressionLarge national databaseICD-9 codingAdministrative billing codesFracture patientsIndividual comorbiditiesPatient comorbiditiesComorbidity diagnosesProspective studyTrauma populationMyocardial infarction
2014
Morbid obesity predisposes trauma patients to worse outcomes
Ditillo M, Pandit V, Rhee P, Aziz H, Hadeed S, Bhattacharya B, Friese RS, Davis K, Joseph B. Morbid obesity predisposes trauma patients to worse outcomes. Journal Of Trauma And Acute Care Surgery 2014, 76: 176-179. PMID: 24368375, DOI: 10.1097/ta.0b013e3182ab0d7c.Peer-Reviewed Original ResearchConceptsBlunt traumatic injuryMorbidly obese patientsInjury Severity ScoreObese patientsGlasgow Coma ScaleHospital complicationsMorbid obesityTraumatic injuryNonobese patientsTrauma patientsIntensive care unit stayNational Trauma Data BankBlunt trauma patientsLonger hospital stayImpact of obesitySystolic blood pressureOverall mortality rateTrauma Data BankInjury prevention effortsConsequences of obesityTraumatic brain injuryUnit stayHospital staySecondary outcomesBlood pressure
2013
When the ICU is the operating room
Piper GL, Maerz LL, Schuster KM, Maung AA, Luckianow GM, Davis KA, Kaplan LJ. When the ICU is the operating room. Journal Of Trauma And Acute Care Surgery 2013, 74: 871-875. PMID: 23425750, DOI: 10.1097/ta.0b013e31827e9c52.Peer-Reviewed Original ResearchConceptsSurgical intensive care unitOperating roomOperative locationICU casesEmergency general surgery patientsGeneral surgery patientsTotal operative casesType of anesthesiaIntensive care unitMode of ventilationT-testStudent's t-testSurgery patientsCare unitNeuromuscular blockadeAdverse outcomesDeep sedationProcedure typeOperative procedureSurgical proceduresEpidemiologic studiesICU databaseCase volumeLevel ITotal cases
2012
Compared to conventional ventilation, airway pressure release ventilation may increase ventilator days in trauma patients
Maung AA, Schuster KM, Kaplan LJ, Ditillo MF, Piper GL, Maerz LL, Lui FY, Johnson DC, Davis KA. Compared to conventional ventilation, airway pressure release ventilation may increase ventilator days in trauma patients. Journal Of Trauma And Acute Care Surgery 2012, 73: 507-510. PMID: 23019679, DOI: 10.1097/ta.0b013e31825ff653.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedContinuous Positive Airway PressureCritical CareDatabases, FactualFemaleFollow-Up StudiesHumansInjury Severity ScoreIntra-Abdominal HypertensionLength of StayLinear ModelsMaleMiddle AgedMultivariate AnalysisPulmonary Gas ExchangeRespiration, ArtificialRetrospective StudiesRisk AssessmentSurvival RateTime FactorsTrauma CentersTreatment OutcomeVentilator WeaningWounds and InjuriesConceptsAirway pressure release ventilationTotal ventilator daysVentilator daysHospital complicationsMechanical ventilationAIS scoreChest Abbreviated Injury Scale scoreAbbreviated Injury Scale scoreSpontaneous breathing trialAbdominal compartment syndromeAcute lung injuryAcute renal failureInjury Scale scoreStudy entry criteriaInjury Severity ScorePotential confounding factorsAPRV groupAPRV modeBreathing trialRescue therapyCompartment syndromeLung injuryRenal failureIndependent predictorsRetrospective review
2011
Risk of Venous Thromboembolism After Spinal Cord Injury: Not All Levels Are the Same
Maung AA, Schuster KM, Kaplan LJ, Maerz LL, Davis KA. Risk of Venous Thromboembolism After Spinal Cord Injury: Not All Levels Are the Same. Journal Of Trauma And Acute Care Surgery 2011, 71: 1241-1245. PMID: 22071925, DOI: 10.1097/ta.0b013e318235ded0.Peer-Reviewed Original ResearchConceptsLevel of SCISpinal cord injuryRate of VTEIndependent risk factorVenous thromboembolismRisk factorsHospital complicationsSpine injuriesCord injuryHigh thoracic spinal cord injuryHigh cervical spine injuryLikelihood of VTENational Trauma Data BankThoracic spinal cord injuryMultiple logistic regression modelException of pneumoniaHigh thoracic injuriesInjury Severity ScoreThoracic spine injuriesCervical spine injuryDeep vein thrombosisHigh cervical injuriesTrauma Data BankMultiple risk factorsTraumatic brain injuryRoutine or Protocol Evaluation of Trauma Patients With Suspected Syncope is Unnecessary
Maung AA, Kaplan LJ, Schuster KM, Johnson DC, Davis KA. Routine or Protocol Evaluation of Trauma Patients With Suspected Syncope is Unnecessary. Journal Of Trauma And Acute Care Surgery 2011, 70: 428-432. PMID: 21307745, DOI: 10.1097/ta.0b013e31820958be.Peer-Reviewed Original ResearchConceptsDiagnostic workupCardiac enzymesSyncope workupAbnormal resultsStudy entry criteriaInjury Severity ScoreCause of injuryMotor vehicle collisionsSignificant abnormal resultsStandardized workupRetrospective reviewTrauma patientsCarotid duplexPhysical examinationSeverity scoreTomography angiographyEntry criteriaFemale genderFurther interventionClinical informationLevel ISyncopePatientsSubsequent interventionsWorkup
2010
Factors Associated With Survival Following Blunt Chest Trauma in Older Patients: Results From a Large Regional Trauma Cooperative
Harrington DT, Phillips B, Machan J, Zacharias N, Velmahos GC, Rosenblatt MS, Winston E, Patterson L, Desjardins S, Winchell R, Brotman S, Churyla A, Schulz JT, Maung AA, Davis KA. Factors Associated With Survival Following Blunt Chest Trauma in Older Patients: Results From a Large Regional Trauma Cooperative. JAMA Surgery 2010, 145: 432-437. PMID: 20479340, DOI: 10.1001/archsurg.2010.71.Peer-Reviewed Original ResearchConceptsHigh-volume trauma centerInjury Severity ScoreCongestive heart failurePatient-controlled analgesiaRib fracturesTrauma centerSeverity scoreOlder patientsHeart failureMultivariable analysisTraumatic rib fracturesBlunt chest traumaPatient dataDevelopment of pneumoniaCoronary artery diseaseLevel I centersTraumatic chest injuriesStandard care practicesChest scoreChest traumaArtery diseaseImproved survivalIndependent predictorsPatient factorsUnivariable analysis
2008
Trauma Team Oversight Improves Efficiency of Care and Augments Clinical and Economic Outcomes
Davis KA, Cabbad NC, Schuster KM, Kaplan LJ, Carusone C, Leary T, Udelsman R. Trauma Team Oversight Improves Efficiency of Care and Augments Clinical and Economic Outcomes. Journal Of Trauma And Acute Care Surgery 2008, 65: 1236-1244. PMID: 19077607, DOI: 10.1097/ta.0b013e31818ba311.Peer-Reviewed Original ResearchMeSH KeywordsAbbreviated Injury ScaleConnecticutCost-Benefit AnalysisCross-Sectional StudiesEfficiency, OrganizationalFees, MedicalHospital CostsHumansInjury Severity ScoreLength of StayLinear ModelsMultiple TraumaOutcome and Process Assessment, Health CarePatient Care TeamPersonnel Administration, HospitalQuality Assurance, Health CareTrauma CentersUtilization ReviewConceptsInjury Severity ScoreEfficiency of careHospital lengthTrauma serviceFull-time trauma surgeonsMean Injury Severity ScoreMedian Injury Severity ScoreTrauma team activation criteriaLevel I trauma centerPercentage of patientsShorter hospital lengthI trauma centerLength of stayActual hospital costsMost patientsPatient demographicsTrauma activationsTrauma centerHospital contribution marginInjury patternsSeverity scoreHospital costsPatient managementTrauma surgeonsPatients
2006
Ventilator-Associated Pneumonia, Like Real Estate: Location Really Matters
Eckert MJ, Davis KA, Reed RL, Esposito TJ, Santaniello JM, Poulakidas S, Gamelli RL, Luchette FA. Ventilator-Associated Pneumonia, Like Real Estate: Location Really Matters. Journal Of Trauma And Acute Care Surgery 2006, 60: 104-110. PMID: 16456443, DOI: 10.1097/01.ta.0000197376.98296.7c.Peer-Reviewed Original ResearchConceptsVentilator-associated pneumoniaLogistic regression analysisLower injury severityField intubationTrauma patientsInjury severityDevelopment of VAPHigher Glasgow Coma Scale scoreLower Injury Severity ScoreGlasgow Coma Scale scoreEmergency department intubationInjury Severity ScoreRegression analysisED intubationRetrospective reviewPrehospital intubationSeverity scoreTrauma ScoreInpatient rateIntubationHigh incidencePneumoniaPatientsED groupScale score
2004
Use of Presumptive Antibiotics following Tube Thoracostomy for Traumatic Hemopneumothorax in the Prevention of Empyema and Pneumonia—A Multi-Center Trial
Maxwell RA, Campbell DJ, Fabian TC, Croce MA, Luchette FA, Kerwin AJ, Davis KA, Nagy K, Tisherman S. Use of Presumptive Antibiotics following Tube Thoracostomy for Traumatic Hemopneumothorax in the Prevention of Empyema and Pneumonia—A Multi-Center Trial. Journal Of Trauma And Acute Care Surgery 2004, 57: 742-749. PMID: 15514527, DOI: 10.1097/01.ta.0000147481.42186.42.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntibiotic ProphylaxisCefazolinChest TubesDevice RemovalDouble-Blind MethodEmpyema, PleuralFemaleFollow-Up StudiesHemopneumothoraxHumansInjury Severity ScoreLogistic ModelsMaleMiddle AgedMultivariate AnalysisPneumonia, BacterialProspective StudiesReference ValuesRisk AssessmentThoracic InjuriesThoracostomyTrauma CentersTreatment OutcomeConceptsIncidence of empyemaRisk of empyemaPresumptive antibioticsTube thoracostomyTraumatic hemopneumothoraxDouble-blind trialUse of cefazolinLogistic regression analysisTube thoracostomy placementCenter trialTube placementInjury scoreAntibiotic useGroup A.EmpyemaThoracostomy placementChi analysisPneumoniaThoracostomyHemopneumothoraxPatientsRegression analysisAntibioticsInjuryIncidenceUrgent Airways After Trauma: Who Gets Pneumonia?
Eckert MJ, Davis KA, Reed RL, Santaniello JM, Poulakidas S, Esposito TJ, Luchette FA. Urgent Airways After Trauma: Who Gets Pneumonia? Journal Of Trauma And Acute Care Surgery 2004, 57: 750-755. PMID: 15514528, DOI: 10.1097/01.ta.0000147499.73570.12.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionCohort StudiesEmergency TreatmentFemaleHumansIncidenceInjury Severity ScoreIntubation, IntratrachealMaleMiddle AgedPneumonia, BacterialPredictive Value of TestsProbabilityPrognosisRegression AnalysisRetrospective StudiesRisk AssessmentSex DistributionSurvival AnalysisTracheostomyTrauma CentersWounds and InjuriesConceptsIndependent risk factorDevelopment of pneumoniaRisk factorsEmergency departmentField intubationEmergent intubationLower Glasgow Coma Scale scoreGlasgow Coma Scale scoreMultiple logistic regression analysisPost-traumatic pneumoniaPre-hospital areaIncidence of pneumoniaLower GCS scoreSevere head injuryLogistic regression analysisSeverity of injuryAIS extremityAIS headED intubationHigher ISSHospital lengthGCS scoreRetrospective reviewTrauma patientsBlunt traumaTen Year Experience of Burn, Trauma, and Combined Burn/Trauma Injuries Comparing Outcomes
Santaniello JM, Luchette FA, Esposito TJ, Gunawan H, Reed RL, Davis KA, Gamelli RL. Ten Year Experience of Burn, Trauma, and Combined Burn/Trauma Injuries Comparing Outcomes. Journal Of Trauma And Acute Care Surgery 2004, 57: 696-701. PMID: 15514521, DOI: 10.1097/01.ta.0000140480.50079.a8.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionAgedBurn UnitsBurnsBurns, InhalationCause of DeathChildCombined Modality TherapyCritical CareFemaleFollow-Up StudiesHumansInjury Severity ScoreLogistic ModelsMaleMiddle AgedMultiple TraumaMultivariate AnalysisPredictive Value of TestsRegistriesRetrospective StudiesRisk AssessmentSex DistributionSurvival AnalysisTrauma CentersTreatment OutcomeConceptsInjury Severity ScoreNational Trauma Data BankLength of stayNational Burn RepositoryInhalation injuryIndependent predictorsMultiple logistic regressionInjury patternsPercent total body surface area burnsTotal body surface area burnsBody surface area burnsLogistic regressionT patientsBurn/traumaRare injury patternSurface area burnsTrauma Data BankT-testStudent's t-testTrauma patientsRetrospective reviewTrauma registryPatient populationComparing outcomesSeverity score
2002
Resuscitation in the Pediatric Trauma Population: Admission Base Deficit Remains an Important Prognostic Indicator
Randolph LC, Takacs M, Davis KA. Resuscitation in the Pediatric Trauma Population: Admission Base Deficit Remains an Important Prognostic Indicator. Journal Of Trauma And Acute Care Surgery 2002, 53: 838-842. PMID: 12435932, DOI: 10.1097/00005373-200211000-00006.Peer-Reviewed Original ResearchConceptsAdmission base deficitHours of admissionBase deficitTrauma patientsPediatric populationPrognostic indicatorLower Glasgow Coma Scale scoreLower Pediatric Trauma ScoresHigher Injury Severity ScorePediatric intensive care unitGlasgow Coma Scale scoreNormal base deficitAdult trauma centersAdult trauma patientsPediatric trauma patientsPercent of patientsInjury Severity ScorePediatric trauma populationIntensive care unitPoor prognostic indicatorImportant prognostic indicatorPediatric Trauma ScoreClosed head injuryPosttraumatic shockOverall mortalityHandsewn versus Stapled Anastomosis in Penetrating Colon Injuries Requiring Resection: A Multicenter Study
Demetriades D, Murray JA, Chan LS, Ordoñez C, Bowley D, Nagy KK, Cornwell EE, Velmahos GC, Muñoz N, Hatzitheofilou C, Schwab CW, Rodriguez A, Cornejo C, Davis KA, Namias N, Wisner DH, Ivatury RR, Moore EE, Acosta JA, Maull KI, Thomason MH, Spain DA. Handsewn versus Stapled Anastomosis in Penetrating Colon Injuries Requiring Resection: A Multicenter Study. Journal Of Trauma And Acute Care Surgery 2002, 52: 117-121. PMID: 11791061, DOI: 10.1097/00005373-200201000-00020.Peer-Reviewed Original ResearchConceptsAbdominal complicationsStapled groupColon resectionBlood transfusionMulticenter studyOdds ratioMultivariate analysisPenetrating Abdominal Trauma IndexMultivariate logistic regression analysisAbdominal trauma indexElective colon surgeryEmergency trauma surgeryIndependent risk factorProspective multicenter studySecond multivariate analysisLogistic regression analysisMethod of anastomosisHandsewn groupAntibiotic prophylaxisPrimary anastomosisAnastomotic leakColon surgeryOverall incidencePreoperative delayRisk factors