2023
Guideline-Directed Medical Therapy and Long-Term Mortality and Amputation Outcomes in Patients Undergoing Peripheral Vascular Interventions
Smolderen K, Romain G, Provance J, Scierka L, Mao J, Goodney P, Henke P, Sedrakyan A, Mena-Hurtado C. Guideline-Directed Medical Therapy and Long-Term Mortality and Amputation Outcomes in Patients Undergoing Peripheral Vascular Interventions. JACC Cardiovascular Interventions 2023, 16: 332-343. PMID: 36792257, PMCID: PMC10359106, DOI: 10.1016/j.jcin.2022.09.022.Peer-Reviewed Original ResearchConceptsGuideline-directed medical therapyPeripheral vascular interventionsMedical therapyVascular interventionsEnzyme inhibitors/angiotensin receptor blockersVascular Quality Initiative registryAngiotensin receptor blockersLong-term mortalityRisk of amputationRisk of mortalityNational quality registryQuality improvement effortsAmputation outcomesAmputation riskMajor amputationAntiplatelet therapyCause mortalityReceptor blockersMean ageVascular careQuality registryObservational studyMortality riskHigh riskAmputation data
2022
Association of depression and anxiety disorders with outcomes after revascularization in chronic limb-threatening ischemia hospitalizations nationwide
Harris KM, Mena-Hurtado C, Burg MM, Vriens PW, Heyligers J, Smolderen KG. Association of depression and anxiety disorders with outcomes after revascularization in chronic limb-threatening ischemia hospitalizations nationwide. Journal Of Vascular Surgery 2022, 77: 480-489. PMID: 36115521, DOI: 10.1016/j.jvs.2022.09.008.Peer-Reviewed Original ResearchConceptsLength of stayChronic limb-threatening ischemiaAnxiety disorder diagnosisAssociation of depressionRevascularization cohortMajor amputationDisorder diagnosisSurgical revascularizationEndovascular revascularizationHigher oddsLonger median LOSMedian LOSLonger LOSAnxiety disordersDocumentation of depressionPeripheral artery diseaseLimb-threatening ischemiaRisk of amputationNational Inpatient SamplePatients' sociodemographic dataHigher median costArtery diseaseIllness severityPsychiatric comorbidityComorbid depression