2020
Association of Perceived Stress Levels With Long-term Mortality in Patients With Peripheral Artery Disease
Malik AO, Peri-Okonny P, Gosch K, Thomas M, Mena C, Hiatt WR, Jones PG, Provance JB, Labrosciano C, Jelani QU, Spertus JA, Smolderen KG. Association of Perceived Stress Levels With Long-term Mortality in Patients With Peripheral Artery Disease. JAMA Network Open 2020, 3: e208741. PMID: 32573710, PMCID: PMC7312389, DOI: 10.1001/jamanetworkopen.2020.8741.Peer-Reviewed Original ResearchConceptsModifiable risk factorsSelf-perceived stressChronic stressCause mortalityCohort studyRisk factorsCox proportional hazards regression modelLong-term mortality riskProportional hazards regression modelsSymptoms of PADLong-term mortalityPeripheral arterial diseasePeripheral artery diseasePrimary study outcomeEvidence-based management strategiesNational Death IndexHazards regression modelsRisk of mortalityAssessment of mortalityOnly patientsArtery diseaseFinal cohortArterial diseaseDeath IndexMulticenter study
2017
Depression Treatment and 1-Year Mortality After Acute Myocardial Infarction
Smolderen KG, Buchanan DM, Gosch K, Whooley M, Chan PS, Vaccarino V, Parashar S, Shah AJ, Ho PM, Spertus JA. Depression Treatment and 1-Year Mortality After Acute Myocardial Infarction. Circulation 2017, 135: 1681-1689. PMID: 28209727, PMCID: PMC5796757, DOI: 10.1161/circulationaha.116.025140.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntidepressive AgentsCause of DeathDepressionFemaleHealth StatusHumansKaplan-Meier EstimateMaleMental HealthMiddle AgedMyocardial InfarctionProportional Hazards ModelsProspective StudiesPsychiatric Status Rating ScalesQuality of LifeRegistriesRisk AssessmentRisk FactorsSurveys and QuestionnairesTime FactorsTreatment OutcomeUnited StatesConceptsAcute myocardial infarctionPatient Health Questionnaire-9Untreated depressionMyocardial infarctionObservational multicenter cohort studyMulticenter cohort studyOne-year mortalityLong-term mortalityPrognosis of patientsPHQ-9 scoresTreatment of depressionPHQ-9 criteriaAMI severityPHQ scoresTRIUMPH studyCohort studyClinical factorsDepression treatmentDischarge diagnosisQuestionnaire-9Medical recordsAMI admissionsPatientsBetter outcomesMortality rate
2014
Peripheral arterial disease, gender, and depression in the Heart and Soul Study
Grenon SM, Cohen BE, Smolderen K, Vittinghoff E, Whooley MA, Hiramoto J. Peripheral arterial disease, gender, and depression in the Heart and Soul Study. Journal Of Vascular Surgery 2014, 60: 396-403. PMID: 24661811, PMCID: PMC4199228, DOI: 10.1016/j.jvs.2014.02.013.Peer-Reviewed Original ResearchConceptsPeripheral arterial diseaseRisk factorsArterial diseaseDevelopment of PADStable coronary artery diseaseGender-specific risk factorsNontraditional risk factorsProspective cohort studyWorse lipid profileHistory of smokingTraditional risk factorsCoronary artery diseaseStrongest independent factorRole of depressionLogistic regression modelsSoul StudyCohort studyInflammatory biomarkersArtery diseaseDiabetes mellitusElevated fibrinogenSimilar prevalenceLipid profileHigh prevalenceIndependent factorsDeterminants of invasive treatment in lower extremity peripheral arterial disease
van Zitteren M, Vriens PW, Burger DH, de Fijter WM, Gerritsen GP, Heyligers JM, Nooren MJ, Smolderen KG. Determinants of invasive treatment in lower extremity peripheral arterial disease. Journal Of Vascular Surgery 2014, 59: 400-408.e2. PMID: 24461863, DOI: 10.1016/j.jvs.2013.08.045.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnkle Brachial IndexChi-Square DistributionDecision Support TechniquesEndovascular ProceduresFemaleHealth StatusHumansLower ExtremityMaleMiddle AgedNetherlandsOdds RatioPatient SelectionPeripheral Arterial DiseasePredictive Value of TestsProspective StudiesReferral and ConsultationRisk FactorsTreatment OutcomeUltrasonography, Doppler, DuplexVascular Surgical ProceduresConceptsPeripheral arterial diseaseLower extremity peripheral arterial diseasePhysical component scaleInvasive treatmentLesion locationHealth statusArterial diseaseTreatment referralSymptomatic lower extremity peripheral arterial diseaseProspective observational cohort studyVascular surgery outpatient clinicProximal lesion locationAnkle-brachial indexObservational cohort studySurgery outpatient clinicShort Form-12Poor health statusPatients' health statusPoisson regression analysisPAD diagnosisCohort studyPAD symptomsIndependent predictorsAmbulatory patientsForm-12
2013
Preoperative Anxiety as a Predictor of Mortality and Major Morbidity in Patients Aged >70 Years Undergoing Cardiac Surgery
Williams JB, Alexander KP, Morin JF, Langlois Y, Noiseux N, Perrault LP, Smolderen K, Arnold SV, Eisenberg MJ, Pilote L, Monette J, Bergman H, Smith PK, Afilalo J. Preoperative Anxiety as a Predictor of Mortality and Major Morbidity in Patients Aged >70 Years Undergoing Cardiac Surgery. The American Journal Of Cardiology 2013, 111: 137-142. PMID: 23245838, PMCID: PMC3677723, DOI: 10.1016/j.amjcard.2012.08.060.Peer-Reviewed Original ResearchConceptsMajor morbidityCardiac surgeryHigh preoperative anxietyPreoperative anxietyHospital AnxietyDepression ScaleThoracic surgeonsProspective multicenter cohort studyMultivariable logistic regression analysisPatient-reported anxietyMulticenter cohort studyPredictors of mortalityTertiary care hospitalType of surgeryMain outcome measuresRisk of mortalityDepression Scale scoresPrimary predictor variableLogistic regression analysisPatients AgedPostoperative mortalityCause mortalityFrailty assessmentIndex hospitalizationCohort study