2024
Four-factor prothrombin complex concentrate is not inferior to andexanet alfa for the reversal or oral factor Xa inhibitors: An Eastern Association for the Surgery of Trauma multicenter study
Estroff J, Devlin J, Hoteit L, Hassoune A, Neal M, Brown J, Lu L, Kotch S, Hazelton J, Christian A, Yeates E, Nahmias J, Jacobson L, Williams J, Schuster K, O'Connor R, Semon G, Straughn A, Cullinane D, Egodage T, Kincaid M, Rollins A, Amdur R, Sarani B. Four-factor prothrombin complex concentrate is not inferior to andexanet alfa for the reversal or oral factor Xa inhibitors: An Eastern Association for the Surgery of Trauma multicenter study. Journal Of Trauma And Acute Care Surgery 2024, 97: 541-545. PMID: 38685190, DOI: 10.1097/ta.0000000000004345.Peer-Reviewed Original ResearchProthrombin complex concentrateAmount of RBC transfusionRed blood cell transfusionAndexanet alfaRed blood cellsRBC transfusionMulticenter study of adult patientsNon-inferiorityComparing prothrombin complex concentrateOral factor Xa inhibitorsStudy of adult patientsTransfused red blood cellsIncreased RBC transfusionsReversal of DOACsComplex concentrateFactor Xa inhibitorsTreatment of hemorrhageTraumatically injured patientsDOAC reversalMedian transfusionTransfusion rateUnit transfusionsMulticenter studyAdult patientsXa inhibitors
2020
Transfusion rates in emergency general surgery: high but modifiable
Medvecz A, Bernard A, Hamilton C, Schuster KM, Guillamondegui O, Davenport D. Transfusion rates in emergency general surgery: high but modifiable. Trauma Surgery & Acute Care Open 2020, 5: e000371. PMID: 32154373, PMCID: PMC7046949, DOI: 10.1136/tsaco-2019-000371.Peer-Reviewed Original ResearchNational Surgical Quality Improvement Program dataTransfusion rateRed blood cellsRBC transfusionSurgeons National Surgical Quality Improvement Program dataEmergency general surgery casesQuality Improvement Program dataBlood conservation technologiesNon-emergent casesCurrent Procedural Terminology codesEmergency general surgeryGeneral surgery casesProcedural Terminology codesAcademic medical centerComposite morbidityNSQIP complicationsRetrospective reviewSurgery casesGeneral surgeonsMedical CenterAmerican CollegeGeneral surgeryTerminology codesTransfusionPatient acuity