1998
Vigabatrin increases human brain homocarnosine and improves seizure control
Petroff O, Mattson R, Behar K, Hyder F, Rothman D. Vigabatrin increases human brain homocarnosine and improves seizure control. Annals Of Neurology 1998, 44: 948-952. PMID: 9851440, DOI: 10.1002/ana.410440614.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidSeizure controlGABA concentrationAddition of vigabatrinLow-dose vigabatrinImproved seizure controlMean GABA concentrationAntiepileptic drug vigabatrinInhibitory neuromodulatorDaily doseGABAergic neuronsGABA levelsLarge dosesHomocarnosine concentrationsVigabatrinDrug vigabatrinHomocarnosinePatientsHuman brainMagnetic resonance spectroscopyControlNeuromodulatorsNeuronsDoseDoses15N-NMR Spectroscopy Studies of Ammonia Transport and Glutamine Synthesis in the Hyperammonemic Rat Brain
Shen J, Sibson N, Cline G, Behar K, Rothman D, Shulman R. 15N-NMR Spectroscopy Studies of Ammonia Transport and Glutamine Synthesis in the Hyperammonemic Rat Brain. Developmental Neuroscience 1998, 20: 434-443. PMID: 9778582, DOI: 10.1159/000017341.Peer-Reviewed Original Research
1985
Cerebral intracellular pH by 31P nuclear magnetic resonance spectroscopy.
Petroff O, Prichard J, Behar K, Alger J, den Hollander J, Shulman R. Cerebral intracellular pH by 31P nuclear magnetic resonance spectroscopy. Neurology 1985, 35: 781-8. PMID: 4000479, DOI: 10.1212/wnl.35.6.781.Peer-Reviewed Original Research