Risk of Subsequent Central Nervous System Neoplasms in Childhood Cancer Survivors after Radiation Therapy: Results from the Pediatric Normal Tissue Effects in the Clinic (PENTEC) Collaboration
Casey D, Brodin P, Roberts K, Vogelius I, Avanzo M, Moni J, Owens C, Ronckers C, Constine L, Bentzen S, Olch A. Risk of Subsequent Central Nervous System Neoplasms in Childhood Cancer Survivors after Radiation Therapy: Results from the Pediatric Normal Tissue Effects in the Clinic (PENTEC) Collaboration. International Journal Of Radiation Oncology • Biology • Physics 2022, 114: s122-s123. DOI: 10.1016/j.ijrobp.2022.07.568.Peer-Reviewed Original ResearchSubsequent malignant tumorChildhood cancer survivorsMalignant CNS tumorsSubsequent meningiomaExcess odds ratioMalignant tumorsRadiation therapyCancer survivorsRT doseCNS tumorsOdds ratioHigh riskPediatric Normal Tissue EffectsPrior cranial radiation therapyCentral nervous system neoplasmsRadiation dose-response relationshipMalignant CNS tumorPrimary cancer diagnosisCranial radiation therapyNervous system neoplasmsIndependent patient cohortsDifferent dose intervalsNormal tissue effectsDose-response relationshipMATERIAL/METHODS