2012
Structural diversity and African origin of the 17q21.31 inversion polymorphism
Steinberg KM, Antonacci F, Sudmant PH, Kidd JM, Campbell CD, Vives L, Malig M, Scheinfeldt L, Beggs W, Ibrahim M, Lema G, Nyambo TB, Omar SA, Bodo JM, Froment A, Donnelly MP, Kidd KK, Tishkoff SA, Eichler EE. Structural diversity and African origin of the 17q21.31 inversion polymorphism. Nature Genetics 2012, 44: 872-880. PMID: 22751100, PMCID: PMC3408829, DOI: 10.1038/ng.2335.Peer-Reviewed Original Research
2011
Diversification of the ADH1B Gene during Expansion of Modern Humans
Li H, Gu S, Han Y, Xu Z, Pakstis AJ, Jin L, Kidd JR, Kidd KK. Diversification of the ADH1B Gene during Expansion of Modern Humans. Annals Of Human Genetics 2011, 75: 497-507. PMID: 21592108, PMCID: PMC3722864, DOI: 10.1111/j.1469-1809.2011.00651.x.Peer-Reviewed Original ResearchConceptsShort tandem repeat polymorphismsSingle nucleotide polymorphismsGeographic patternsAncient DNA samplesADH1B geneSelective forcesRegulatory region variantsUnusual geographic distributionMigration eventsCommon haplogroupsDistinct geographic patternsGeographic distributionGenesNucleotide polymorphismsEast Asian populationsTandem repeat polymorphismDNA samplesHaplogroupsWorldwide setAllelesModern humansRegion variantsRepeat polymorphismPolymorphismEast AsiaHunter-gatherer genomic diversity suggests a southern African origin for modern humans
Henn BM, Gignoux CR, Jobin M, Granka JM, Macpherson JM, Kidd JM, Rodríguez-Botigué L, Ramachandran S, Hon L, Brisbin A, Lin AA, Underhill PA, Comas D, Kidd KK, Norman PJ, Parham P, Bustamante CD, Mountain JL, Feldman MW. Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 108: 5154-5162. PMID: 21383195, PMCID: PMC3069156, DOI: 10.1073/pnas.1017511108.Peer-Reviewed Original ResearchConceptsHunter-gatherer populationsAfrican hunter-gatherer populationsModern humansGenome-wide linkage disequilibriumModern human populationsSex-biased migrationSevere population bottleneckLinkage disequilibriumSouthern African originHuman prehistoryAfrican populationsComplex historyPopulation differentiationPopulation bottlenecksGenetic diversityGenomic diversityEastern AfricaGenetic variationAfrican originPopulation todaySouthern AfricaGeographic patternsContinent of originAfricaSouth Africa
2001
Modern African Ape Populations as Genetic and Demographic Models of the Last Common Ancestor of Humans, Chimpanzees, and Gorillas
Jensen-Seaman M, Deinard A, Kidd K. Modern African Ape Populations as Genetic and Demographic Models of the Last Common Ancestor of Humans, Chimpanzees, and Gorillas. Journal Of Heredity 2001, 92: 475-480. PMID: 11948214, DOI: 10.1093/jhered/92.6.475.Peer-Reviewed Original ResearchConceptsLast common ancestorEffective population sizeNucleotide diversityCommon ancestorStrong female philopatryStrong geographic structuringPopulation sizeHuman evolutionary historyNuclear lociGeographic structuringModern humansFemale philopatryEvolutionary historyAncestral populationsGorilla lineageMolecular dataNuclear DNAClose relativesDemographic modelsAfrican ape speciesApe populationsApe speciesNatal groupSpeciesDispersal systemMitochondrial DNA variation and biogeography of eastern gorillas
Jensen‐Seaman M, Kidd K. Mitochondrial DNA variation and biogeography of eastern gorillas. Molecular Ecology 2001, 10: 2241-2247. PMID: 11555266, DOI: 10.1046/j.0962-1083.2001.01365.x.Peer-Reviewed Original ResearchConceptsMitochondrial DNA variationDNA variationEastern gorillasD-loop haplotypesFirst hypervariable segmentPopulation bottlenecksDistinct cladesGenetic diversityControl regionD-loopHypervariable segmentCladeLast Glacial MaximumGorillasForest reductionHaplotypesGlacial MaximumBiogeographyEast AfricaGlobal coolingDiversityMutationsLow levelsVariationFragmentation
2000
Worldwide Genetic Analysis of the CFTR Region
Mateu E, Calafell F, Lao O, Bonné-Tamir B, Kidd J, Pakstis A, Kidd K, Bertranpetit J. Worldwide Genetic Analysis of the CFTR Region. American Journal Of Human Genetics 2000, 68: 103-117. PMID: 11104661, PMCID: PMC1234903, DOI: 10.1086/316940.Peer-Reviewed Original ResearchConceptsCystic fibrosis transmembrane conductance regulator (CFTR) geneShort tandem repeat polymorphismsSingle nucleotide polymorphismsLinkage disequilibriumHaplotype backgroundTransmembrane conductance regulator geneWorldwide population samplesModern human populationsHaplotype variationHigh heterozygosityCFTR regionOut of AfricaRegulator geneSevere genetic disorderGenetic analysisMutation rateDifferent haplotypesAncestral haplotypeAllele sizeOutcome of differencesSNP haplotypesLD analysisNon-AfricansHaplotypesLD measuresHaplotypes and Linkage Disequilibrium at the Phenylalanine Hydroxylase Locus, PAH, in a Global Representation of Populations
Kidd J, Pakstis A, Zhao H, Lu R, Okonofua F, Odunsi A, Grigorenko E, Tamir B, Friedlaender J, Schulz L, Parnas J, Kidd K. Haplotypes and Linkage Disequilibrium at the Phenylalanine Hydroxylase Locus, PAH, in a Global Representation of Populations. American Journal Of Human Genetics 2000, 66: 1882-1899. PMID: 10788337, PMCID: PMC1378054, DOI: 10.1086/302952.Peer-Reviewed Original Research
1996
Interpretations of multiregional evolution.
Wolpoff; M, Tishkoff S, Kidd K, Risch N. Interpretations of multiregional evolution. Science 1996, 274: 704-7. PMID: 8966550, DOI: 10.1126/science.274.5288.704d.Peer-Reviewed Original ResearchMinisatellite diversity supports a recent African origin for modern humans
Armour J, Anttinen T, May C, Vega E, Sajantila A, Kidd J, Kidd K, Bertranpetit J, Pääbo S, Jeffreys A. Minisatellite diversity supports a recent African origin for modern humans. Nature Genetics 1996, 13: 154-160. PMID: 8640220, DOI: 10.1038/ng0696-154.Peer-Reviewed Original ResearchConceptsRecent African originNon-African populationsModern human diversityAllelic diversityMinisatellite diversityVariable lociAncestral relationshipsHuman chromosomesAllelic structureAfrican originGreat diversityDiversityHuman diversityAfrican chromosomesChromosomesAllele familiesLociModern humansDifferent populationsThe world-wide distribution of allele frequencies at the human dopamine D4 receptor locus
Chang F, Kidd J, Livak K, Pakstis A, Kidd K. The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus. Human Genetics 1996, 98: 91-101. PMID: 8682515, DOI: 10.1007/s004390050166.Peer-Reviewed Original ResearchConceptsImperfect tandem repeatsAllele frequenciesDifferent populationsActual allele frequenciesDopamine D4 receptor locusSelective forcesEvolutionary significanceWorld-wide distributionAssociation studiesReceptor locusTandem repeatsThird exonBase pairsAmino acidsFunctional relevanceRepeatsReceptor geneAllelesLociModern humansPolymorphismD4 receptor geneDopamine D4 receptor geneRepeat polymorphismExonsGlobal Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
Tishkoff S, Dietzsch E, Speed W, Pakstis A, Kidd J, Cheung K, Bonné-Tamir B, Santachiara-Benerecetti A, Moral P, Krings M, Pääbo S, Watson E, Risch N, Jenkins T, Kidd K. Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins. Science 1996, 271: 1380-1387. PMID: 8596909, DOI: 10.1126/science.271.5254.1380.Peer-Reviewed Original Research
1991
Study of an additional 58 DNA markers in five human populations from four continents.
Bowcock A, Hebert J, Mountain J, Kidd J, Rogers J, Kidd K, Cavalli-Sforza L. Study of an additional 58 DNA markers in five human populations from four continents. Gene Geography 1991, 5: 151-73. PMID: 1841601.Peer-Reviewed Original Research
1987
Study of 47 DNA markers in five populations from four continents.
Bowcock A, Bucci C, Hebert J, Kidd J, Kidd K, Friedlaender J, Cavalli-Sforza L. Study of 47 DNA markers in five populations from four continents. Gene Geography 1987, 1: 47-64. PMID: 2908691.Peer-Reviewed Original Research