Clinicopathologic Analysis of Ampullary Neoplasms in 450 Patients: Implications for Surgical Strategy and Long-Term Prognosis
Winter JM, Cameron JL, Olino K, Herman JM, de Jong MC, Hruban RH, Wolfgang CL, Eckhauser F, Edil BH, Choti MA, Schulick RD, Pawlik TM. Clinicopathologic Analysis of Ampullary Neoplasms in 450 Patients: Implications for Surgical Strategy and Long-Term Prognosis. Journal Of Gastrointestinal Surgery 2010, 14: 379-387. PMID: 19911239, DOI: 10.1007/s11605-009-1080-7.Peer-Reviewed Original ResearchConceptsLymph node metastasisAmpullary neoplasmsNode metastasisSurgical resectionTumor sizeInvasive adenocarcinomaMicroscopic vessel invasionInitial surgical procedureMedian tumor sizeOutcomes of patientsPoor histologic gradeLong-term prognosisSingle-institution databaseRegional lymph nodesAmpulla of VaterEarly invasive adenocarcinomaDepth of invasionMethodsBetween 1970Metastatic diseaseRadical resectionAmpullary adenomasClinicopathologic factorsLymph nodesClinicopathologic analysisPerineural invasion