A multi-trait epigenome-wide association study identified DNA methylation signature of inflammation among men with HIV
Chen J, Hui Q, Titanji B, So-Armah K, Freiberg M, Justice A, Xu K, Zhu X, Gwinn M, Marconi V, Sun Y. A multi-trait epigenome-wide association study identified DNA methylation signature of inflammation among men with HIV. Clinical Epigenetics 2024, 16: 152. PMID: 39488703, PMCID: PMC11531128, DOI: 10.1186/s13148-024-01763-2.Peer-Reviewed Original ResearchConceptsEpigenome-wide association studiesDNA methylationAssociation studiesDNAm sitesDNA methylation sitesAssociated with DNA methylationDNA methylation signaturesInflammatory markersResponse to virusesImmune response to virusesVeterans Aging Cohort StudySignatures of inflammationGenesIdentified sitesAging Cohort StudyInflammation-related genesPathwayPersistent inflammationMale PWHCohort studyExcess morbidityPWHStudy populationInflammationStatistical power