Regulation of ROMK1 Channels by Protein-tyrosine Kinase and -tyrosine Phosphatase*
Moral Z, Dong K, Wei Y, Sterling H, Deng H, Ali S, Gu R, Huang X, Hebert S, Giebisch G, Wang W. Regulation of ROMK1 Channels by Protein-tyrosine Kinase and -tyrosine Phosphatase*. Journal Of Biological Chemistry 2000, 276: 7156-7163. PMID: 11114300, PMCID: PMC2822675, DOI: 10.1074/jbc.m008671200.Peer-Reviewed Original ResearchMeSH KeywordsAlanineAnimalsBenzoquinonesBlotting, WesternColchicineConcanavalin AEnzyme InhibitorsLactams, MacrocyclicMicroscopy, FluorescenceMicrotubulesModels, BiologicalMutationOocytesPaclitaxelPatch-Clamp TechniquesPotassiumPotassium ChannelsPotassium Channels, Inwardly RectifyingProtein Tyrosine PhosphatasesProtein-Tyrosine KinasesQuinonesRifabutinRNA, ComplementarySucroseTime FactorsTyrosineXenopusConceptsProtein tyrosine phosphataseProtein tyrosine kinasesHerbimycin AEffect of PAOPhenylarsine oxideROMK1 channelsInhibitor of PTPInhibitors of PTKInhibitors of microtubulesTyrosine phosphataseTreatment of oocytesTyrosine residuesPosition 337Western blot analysisCSrcBlot analysisROMK1OocytesKinaseMicrotubulesTwo-electrode voltage-clamp techniquePhosphataseRegulationRat homolog of sulfonylurea receptor 2B determines glibenclamide sensitivity of ROMK2 in Xenopus laevisoocyte
Tanemoto M, Vanoye C, Dong K, Welch R, Abe T, Hebert S, Xu J. Rat homolog of sulfonylurea receptor 2B determines glibenclamide sensitivity of ROMK2 in Xenopus laevisoocyte. American Journal Of Physiology. Renal Physiology 2000, 278: f659-f666. PMID: 10751228, DOI: 10.1152/ajprenal.2000.278.4.f659.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsATP-Binding Cassette TransportersFemaleGlyburideKidneyMolecular Sequence DataOocytesPotassium ChannelsPotassium Channels, Inwardly RectifyingProtein IsoformsRatsReceptors, DrugSequence Homology, Amino AcidSulfonylurea ReceptorsTranscription, GeneticXenopus laevisConceptsThick ascending limbAscending limbCortical thick ascending limbRT-PCRMedullary thick ascending limbGlibenclamide sensitivityGlibenclamide effectsRat homologIntrarenal distributionSulfonylurea receptor 2BProximal tubulesDistal distributionSulfonylurea receptorRenal ATPSkeletal muscleRat tissuesXenopus laevis oocytesROMK proteinGlibenclamideRat kidney cDNA librarySUR2BTubulesROMKLimbLaevis oocytes