An Update on the Treatment of Pediatric Autoimmune Encephalitis
Stingl C, Cardinale K, Van Mater H. An Update on the Treatment of Pediatric Autoimmune Encephalitis. Current Treatment Options In Rheumatology 2018, 4: 14-28. PMID: 29780690, PMCID: PMC5957495, DOI: 10.1007/s40674-018-0089-z.Peer-Reviewed Original ResearchSecond-line therapyRefractory diseaseNeuropsychiatric deficitsProspective randomized placebo-controlled trialInterleukin-6 inhibitor tocilizumabLow-dose IL-2Randomized placebo-controlled trialPediatric autoimmune encephalitisPlacebo-controlled trialEarly treatment initiationFirst-line therapyFirst-line treatmentSecond-line agentsIL-6 blockadeMajority of patientsProteasome inhibitorsRecent FindingsTo dateAutoimmune encephalitisTreatment escalationIntravenous immunoglobulinMycophenolate mofetilClinical improvementPharmacologic treatmentPrompt treatmentTreatment initiation