Atypical small acinar proliferation (ASAP): Is a repeat biopsy necessary ASAP? A multi-institutional review
Leone A, Gershman B, Rotker K, Butler C, Fantasia J, Miller A, Afiadata A, Amin A, Zhou A, Jiang Z, Sebo T, Mega A, Schiff S, Pareek G, Golijanin D, Yates J, Karnes RJ, Renzulli J. Atypical small acinar proliferation (ASAP): Is a repeat biopsy necessary ASAP? A multi-institutional review. Prostate Cancer And Prostatic Diseases 2015, 19: 68-71. PMID: 26857145, DOI: 10.1038/pcan.2015.52.Peer-Reviewed Original ResearchConceptsAtypical small acinar proliferationHigh-grade prostate cancerImmediate repeat biopsySmall acinar proliferationMulti-institutional reviewRepeat biopsySubsequent prostate cancerProstate cancerAcinar proliferationInitial diagnosisProstate biopsyRetrospective multi-institutional reviewAbnormal digital rectal examTransrectal ultrasound-guided biopsyPre-biopsy PSAHigh-grade diseaseDigital rectal examUltrasound-guided biopsyUnderwent repeat biopsyMajority of menElevated PSAGleason 7Clinicopathologic featuresRectal examHigher PSA