2022
Hypoconnectivity between anterior insula and amygdala associates with future vulnerabilities in social development in a neurodiverse sample of neonates
Scheinost D, Chang J, Lacadie C, Brennan-Wydra E, Foster R, Boxberger A, Macari S, Vernetti A, Constable RT, Ment LR, Chawarska K. Hypoconnectivity between anterior insula and amygdala associates with future vulnerabilities in social development in a neurodiverse sample of neonates. Scientific Reports 2022, 12: 16230. PMID: 36171268, PMCID: PMC9517994, DOI: 10.1038/s41598-022-20617-6.Peer-Reviewed Original ResearchConceptsFirst Year InventoryAnterior insulaFunctional connectivityMaternal mental health factorsLeft anterior insulaState functional connectivityMental health factorsSubsample of participantsPostmenstrual ageSalience networkFamily historySocial domainsNeural circuitryAutismSocial behaviorBrain imagingHigher likelihoodInsulaSocial developmentHypoconnectivityExploratory analysisThird trimesterFuture onsetHealth factorsRisk score
2014
Screening for Autism Spectrum Disorders in 12-Month-Old High-Risk Siblings by Parental Report
Rowberry J, Macari S, Chen G, Campbell D, Leventhal JM, Weitzman C, Chawarska K. Screening for Autism Spectrum Disorders in 12-Month-Old High-Risk Siblings by Parental Report. Journal Of Autism And Developmental Disorders 2014, 45: 221-229. PMID: 25149178, PMCID: PMC4289092, DOI: 10.1007/s10803-014-2211-x.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderParental reportsSpectrum disorderDevelopmental outcomesHigh-risk siblingsFirst Year InventoryVocal imitationRepetitive behaviorsSocial communicationGreater impairmentClinician ratingsYounger siblingsScreening instrumentPreliminary findingsASD casesImportant implicationsDisordersSiblingsImitationParentsRatingsImpairmentInventoryChildrenCommunication