1996
Effects of continuous glucocorticoid infusion on bone metabolism in the rat
King CS, Weir EC, Gundberg CW, Fox J, Insogna KL. Effects of continuous glucocorticoid infusion on bone metabolism in the rat. Calcified Tissue International 1996, 59: 184-191. PMID: 8694896, DOI: 10.1007/s002239900107.Peer-Reviewed Original ResearchConceptsDEX treatmentBone metabolismUrinary calcium/creatinine ratioCalcium/creatinine ratioIntact parathyroid functionLevels of PTHSprague-Dawley ratsTartrate-resistant acid phosphataseParathyroid functionTime-dependent mannerCreatinine ratioSerum calciumBone turnoverContinuous administrationParathyroidectomized animalsSerum concentrationsSupraphysiologic dosesGlucocorticoid infusionDawley ratsFemoral weightHistomorphometric findingsBone massPTX animalsBone volumeDexamethasone
1985
Elevations in Circulating 1,25-Dihydroxyvitamin D in Three Patients with Lymphoma-Associated Hypercalcemia*
ROSENTHAL N, INSOGNA K, GODSALL J, GAC A, SMALDONE L, WALDRON J, STEWART A. Elevations in Circulating 1,25-Dihydroxyvitamin D in Three Patients with Lymphoma-Associated Hypercalcemia*. The Journal Of Clinical Endocrinology & Metabolism 1985, 60: 29-33. PMID: 3871092, DOI: 10.1210/jcem-60-1-29.Peer-Reviewed Original ResearchConceptsDihydroxyvitamin DBone marrow biopsyElevated plasma levelsImmunoreactive PTH levelsUrinary cAMP excretionVitamin D metabolitesAdenylate cyclase-stimulating activityCyclase-stimulating activityPTH levelsRadionuclide scansMedical therapyMalignant lymphomaSerum calciumSurgical excisionMarrow biopsyCertain patientsRapid normalizationSplenic lymphomaSystemic mediatorsUrinary excretionD metabolitesPlasma levelsCAMP excretionTumor extractsPatients