2024
Review: Evidence-Based Psychosocial Treatments for Childhood Irritability and Aggressive Behavior
Kalvin C, Zhong J, Rutten M, Ibrahim K, Sukhodolsky D. Review: Evidence-Based Psychosocial Treatments for Childhood Irritability and Aggressive Behavior. JAACAP Open 2024 DOI: 10.1016/j.jaacop.2024.01.009.Peer-Reviewed Original ResearchCognitive-behavioral therapyParent management trainingDialectical behavior therapyChildhood irritabilityChildhood aggressionMaladaptive aggressionPsychosocial treatmentsPsychosocial interventionsReview of evidence-based psychosocial treatmentsDisruptive mood dysregulation disorderEvidence-based psychosocial treatmentsCo-occurring psychopathologySevere mood dysregulationOutpatient mental health servicesChild psychiatric disordersChild mental healthMental health servicesMood dysregulationBehavioral therapyDysregulation disorderPsychiatric disordersDisruptive behaviorWell-powered randomized controlled trialsAggressive behaviorRelevant to clinical practice
2020
Sex differences in medial prefrontal and parietal cortex structure in children with disruptive behavior
Ibrahim K, Kalvin C, Li F, He G, Pelphrey KA, McCarthy G, Sukhodolsky DG. Sex differences in medial prefrontal and parietal cortex structure in children with disruptive behavior. Developmental Cognitive Neuroscience 2020, 47: 100884. PMID: 33254067, PMCID: PMC7704291, DOI: 10.1016/j.dcn.2020.100884.Peer-Reviewed Original ResearchConceptsDisruptive behavior disordersGray matter volumeCortical thicknessMatter volumeSex differencesDisruptive behavior severityCross-sectional studySex-specific associationsDisruptive behaviorLeft ventromedial prefrontal cortexWhole-brain analysisSurface-based morphometryStructural MRI dataHealthy controlsSex-specific differencesNeural biomarkersTarget-based treatmentVentromedial prefrontal cortexMedial prefrontalBehavior disorderPrefrontal cortexBrain structuresSupramarginal gyrusRespective controlsVmPFC volume
2019
Reduced Amygdala–Prefrontal Functional Connectivity in Children With Autism Spectrum Disorder and Co-occurring Disruptive Behavior
Ibrahim K, Eilbott JA, Ventola P, He G, Pelphrey KA, McCarthy G, Sukhodolsky DG. Reduced Amygdala–Prefrontal Functional Connectivity in Children With Autism Spectrum Disorder and Co-occurring Disruptive Behavior. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2019, 4: 1031-1041. PMID: 30979647, PMCID: PMC7173634, DOI: 10.1016/j.bpsc.2019.01.009.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderCallous-unemotional traitsAmygdala-vlPFC connectivityDisruptive behaviorAmygdala reactivityNeural mechanismsSpectrum disorderAmygdala-prefrontal functional connectivityEmotion perception taskFunctional magnetic resonance imagingVentrolateral prefrontal cortexUnderlying neural mechanismsDisruptive behavior disordersTask-specific changesRisk of aggressionEmotion dysregulationFearful facesCalm facesPerception taskFear processingAmygdala activityPsychophysiological interactionAmygdala connectivityExternalizing behaviorsAmygdala hyperactivity
2016
Behavioral Interventions for Anger, Irritability, and Aggression in Children and Adolescents
Sukhodolsky DG, Smith SD, McCauley SA, Ibrahim K, Piasecka JB. Behavioral Interventions for Anger, Irritability, and Aggression in Children and Adolescents. Journal Of Child And Adolescent Psychopharmacology 2016, 26: 58-64. PMID: 26745682, PMCID: PMC4808268, DOI: 10.1089/cap.2015.0120.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyParent management trainingAnger/irritabilityTransdiagnostic approachBehavioral interventionsDisruptive behaviorAggressive behaviorChild disruptive behaviorCallous-unemotional traitsDisruptive behavior disordersTreatment of irritabilityEmotion regulationAversive patternFamily interactionsBehavioral problemsAngerMental health referralsAggressionManagement trainingBehavior disorderMood disordersTreatment targetsIrritabilityChildrenPsychiatric diagnosis