2024
Human brain state dynamics are highly reproducible and associated with neural and behavioral features
Lee K, Ji J, Fonteneau C, Berkovitch L, Rahmati M, Pan L, Repovš G, Krystal J, Murray J, Anticevic A. Human brain state dynamics are highly reproducible and associated with neural and behavioral features. PLOS Biology 2024, 22: e3002808. PMID: 39316635, PMCID: PMC11421804, DOI: 10.1371/journal.pbio.3002808.Peer-Reviewed Original ResearchConceptsCo-activation patternsResting-state functional magnetic resonance imagingFunctional magnetic resonance imagingBehavioral featuresNeural variationsMoment-to-moment changesSingle-subject levelBrain state dynamicsEmotion regulationHealthy young adultsBehavioral phenotypesCognitive functionSubstance useNeural activityNeuroimaging markersNeural featuresYoung adultsMagnetic resonance imagingCo-activationResonance imagingCo-variationNeuroimagingIndividualsEmotionsFunctional outcomesBrain Mappers of Tomorrow: An international multilingual initiative for neuroscience dissemination
Lee K, Borghesani V, de Moraes F, Pozzobon A, Olsen R, Kam J, Tzovara A, Badhwar A. Brain Mappers of Tomorrow: An international multilingual initiative for neuroscience dissemination. Aperture Neuro 2024, 4 DOI: 10.52294/001c.123400.Peer-Reviewed Original ResearchEEG source imaging technique to investigate sleep oscillations for simultaneous EEG-fMRI
Makoto Uji, Aude Jegou, Nathan E Cross, Florence B Pomares, Aurore A Perrault, Alex Nguyen, Umit Aydin, Kangjoo Lee, Chifaou Abdallah, Birgit Frauscher, Jean-Marc Lina, Thien Thanh Dang-Vu, Christophe GrovaPeer-Reviewed Original ResearchCreating diverse and inclusive scientific practices for research datasets and dissemination
Kam J, Badhwar A, Borghesani V, Lee K, Noble S, Raamana P, Ratnanather J, Tan D, Oestreich L, Lee H, Marzetti L, Nakua H, Rippon G, Olsen R, Pozzobon A, Uddin L, Yanes J, Tzovara A. Creating diverse and inclusive scientific practices for research datasets and dissemination. Imaging Neuroscience 2024, 2: 1-14. DOI: 10.1162/imag_a_00216.Commentaries, Editorials and LettersNREM sleep brain networks modulate cognitive recovery from sleep deprivation.
Lee K, Wang Y, Cross NE, Jegou A, Razavipour F, Pomares FB, Perrault AA, Nguyen A, Aydin Ü, Uji M, Abdallah C, Anticevic A, Frauscher B, Benali H, Dang-Vu TT, Grova C. NREM sleep brain networks modulate cognitive recovery from sleep deprivation. BioRxiv 2024 PMID: 39005401, DOI: 10.1101/2024.06.28.601285.Peer-Reviewed Original Research In PressLarge language models surpass human experts in predicting neuroscience results
Xiaoliang Luo, Akilles Rechardt, Guangzhi Sun, Kevin K Nejad, Felipe Yáñez, Bati Yilmaz, Kangjoo Lee, Alexandra O Cohen, Valentina Borghesani, Anton Pashkov, Daniele Marinazzo, Jonathan Nicholas, Alessandro Salatiello, Ilia Sucholutsky, Pasquale Minervini, Sepehr Razavi, Roberta Rocca, Elkhan Yusifov, Tereza Okalova, Nianlong Gu, Martin Ferianc, Mikail Khona, Kaustubh R Patil, Pui-Shee Lee, Rui Mata, Nicholas E Myers, Jennifer K Bizley, Sebastian Musslick, Isil Poyraz Bilgin, Guiomar Niso, Justin M Ales, Michael Gaebler, N Murty, Chloe M Hall, Jessica Dafflon, Sherry Dongqi Bao, Bradley C LovePeer-Reviewed Original Research In Press
2023
A common symptom geometry of mood improvement under sertraline and placebo associated with distinct neural patterns.
Berkovitch L, Lee K, Ji JL, Helmer M, Rahmati M, Demšar J, Kraljič A, Matkovič A, Tamayo Z, Murray JD, Repovš G, Krystal JH, Martin WJ, Fonteneau C, Anticevic A. A common symptom geometry of mood improvement under sertraline and placebo associated with distinct neural patterns. MedRxiv 2023 PMID: 38168378, DOI: 10.1101/2023.12.15.23300019.Peer-Reviewed Original Research In Press217. Mapping Individually Actionable Brain-Behavior Space Variation Across the Mood Spectrum
Berkovitch L, Fonteneau C, Lee K, Ji J, Demšar J, Tamayo Z, Murray J, Repovš G, Anticevic A. 217. Mapping Individually Actionable Brain-Behavior Space Variation Across the Mood Spectrum. Biological Psychiatry 2023, 93: s181. DOI: 10.1016/j.biopsych.2023.02.457.Peer-Reviewed Original Research441. Mapping the Neurobiological and Behavioral Progression of Early Course Schizophrenia
Lin C, Fonteneau C, Lee K, Berkovitch L, Pan L, Tamayo Z, Wei X, Repovš G, Murray J, Lui S, Gong Q, Anticevic A. 441. Mapping the Neurobiological and Behavioral Progression of Early Course Schizophrenia. Biological Psychiatry 2023, 93: s273. DOI: 10.1016/j.biopsych.2023.02.681.Peer-Reviewed Original Research492. Characterizing Thalamocortical Network Development in Psychosis Spectrum Youth
Price A, Fonteneau C, Lee K, Berkovitch L, Ji J, Pan L, Tamayo Z, Afriyie-Agyemang Y, Howell A, Repovš G, Murray J, Cho Y, Anticevic A. 492. Characterizing Thalamocortical Network Development in Psychosis Spectrum Youth. Biological Psychiatry 2023, 93: s293. DOI: 10.1016/j.biopsych.2023.02.732.Peer-Reviewed Original Research
2022
Arousal impacts distributed hubs modulating the integration of brain functional connectivity
Lee K, Horien C, O’Connor D, Garand-Sheridan B, Tokoglu F, Scheinost D, Lake EMR, Constable RT. Arousal impacts distributed hubs modulating the integration of brain functional connectivity. NeuroImage 2022, 258: 119364. PMID: 35690257, PMCID: PMC9341222, DOI: 10.1016/j.neuroimage.2022.119364.Peer-Reviewed Original ResearchA protocol for working with open-source neuroimaging datasets
Horien C, Lee K, Westwater ML, Noble S, Tejavibulya L, Kayani T, Constable RT, Scheinost D. A protocol for working with open-source neuroimaging datasets. STAR Protocols 2022, 3: 101077. PMID: 35036958, PMCID: PMC8749295, DOI: 10.1016/j.xpro.2021.101077.Peer-Reviewed Original Research
2021
An altered balance of integrated and segregated brain activity is a marker of cognitive deficits following sleep deprivation
Cross NE, Pomares FB, Nguyen A, Perrault AA, Jegou A, Uji M, Lee K, Razavipour F, Bin Ka’b Ali O, Aydin U, Benali H, Grova C, Dang-Vu TT. An altered balance of integrated and segregated brain activity is a marker of cognitive deficits following sleep deprivation. PLOS Biology 2021, 19: e3001232. PMID: 34735431, PMCID: PMC8568176, DOI: 10.1371/journal.pbio.3001232.Peer-Reviewed Original ResearchConceptsSleep-deprived stateSleep deprivationCortical networksFunctional magnetic resonance imaging (fMRI) scansLarge-scale cortical networksCognitive impairmentSleep-deprived brainNight of SDHomeostatic sleep pressureExecutive tasksCognitive performanceTask performanceCognitive changesRegular nightBrain activityCognitive functionCognitive deficitsNetwork integrationInformation processingSleep pressureCortical activityBidirectional effectsConnectivity changesInterindividual differencesNonrapid eye movement sleep
2020
Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol
Horien C, Fontenelle S, Joseph K, Powell N, Nutor C, Fortes D, Butler M, Powell K, Macris D, Lee K, Greene AS, McPartland JC, Volkmar FR, Scheinost D, Chawarska K, Constable RT. Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol. Scientific Reports 2020, 10: 21855. PMID: 33318557, PMCID: PMC7736342, DOI: 10.1038/s41598-020-78885-z.Peer-Reviewed Original ResearchConceptsPediatric participantsMRI protocolMagnetic resonance imaging (MRI) scansFunctional magnetic resonance imaging (fMRI) scansShorter MRI protocolsScan protocolResonance imaging scansImaging scansMRI sessionsFMRI connectivity analysisFMRI dataFMRI findingsSignificant confoundScansReplication groupConnectivity analysisAutism spectrum disorderMock scanSpectrum disorderParticipantsHead motionProtocolA hitchhiker’s guide to working with large, open-source neuroimaging datasets
Horien C, Noble S, Greene AS, Lee K, Barron DS, Gao S, O’Connor D, Salehi M, Dadashkarimi J, Shen X, Lake EMR, Constable RT, Scheinost D. A hitchhiker’s guide to working with large, open-source neuroimaging datasets. Nature Human Behaviour 2020, 5: 185-193. PMID: 33288916, PMCID: PMC7992920, DOI: 10.1038/s41562-020-01005-4.Peer-Reviewed Original Research
2019
Effects of sleep deprivation on functional connectivity during a psychomotor vigilance task
Nguyen A, Cross N, Pomares F, Jegou A, Perrault A, Lee K, Smith D, Aydin U, Grova C, Dang-Vu T. Effects of sleep deprivation on functional connectivity during a psychomotor vigilance task. Sleep Medicine 2019, 64: s83. DOI: 10.1016/j.sleep.2019.11.227.Peer-Reviewed Original ResearchCognitive performance and brain activation recovery after a nap following total sleep deprivation
Pomares F, Cross N, Jegou A, Nguyen A, Perrault A, Lee K, Smith D, Aydin U, Grova C, Dang-Vu T. Cognitive performance and brain activation recovery after a nap following total sleep deprivation. Sleep Medicine 2019, 64: s305-s306. DOI: 10.1016/j.sleep.2019.11.856.Peer-Reviewed Original ResearchAutomatic classification and removal of structured physiological noise for resting state functional connectivity MRI analysis
Lee K, Khoo HM, Fourcade C, Gotman J, Grova C. Automatic classification and removal of structured physiological noise for resting state functional connectivity MRI analysis. Magnetic Resonance Imaging 2019, 58: 97-107. PMID: 30695721, DOI: 10.1016/j.mri.2019.01.019.Peer-Reviewed Original ResearchConceptsReal dataNumber of atomsSubject-specific thresholdFunctional connectivity MRI analysisState networksAutomatic removal methodSpatial priorsSet of voxelsBootstrap resamplingSparse dictionary learningStepwise regression procedureNoiseHub analysisRegression procedureInter-network communicationNew methodAtomsBand-pass filteringTemporal correlationFluctuationsPriorsSparsityDictionary learningNetworkWhole-brain signals
2018
Disruption, emergence and lateralization of brain network hubs in mesial temporal lobe epilepsy
Lee K, Khoo HM, Lina JM, Dubeau F, Gotman J, Grova C. Disruption, emergence and lateralization of brain network hubs in mesial temporal lobe epilepsy. NeuroImage Clinical 2018, 20: 71-84. PMID: 30094158, PMCID: PMC6070692, DOI: 10.1016/j.nicl.2018.06.029.Peer-Reviewed Original ResearchConceptsMesial temporal lobe epilepsyTemporal lobe epilepsyLobe epilepsyState functional MRIDefault mode networkHealthy controlsBrain network hubsConnector hubsAbnormal hippocampusMotor networkHippocampal networkBrain regionsSalience networkFunctional MRIEpilepsyEpileptic subjectsMode networkLateralizationBrain networksDefault modeAbnormalitiesPathological disruptionHub reorganizationFunctional networksDisruption
2016
SPARK: Sparsity-based analysis of reliable k-hubness and overlapping network structure in brain functional connectivity
Lee K, Lina JM, Gotman J, Grova C. SPARK: Sparsity-based analysis of reliable k-hubness and overlapping network structure in brain functional connectivity. NeuroImage 2016, 134: 434-449. PMID: 27046111, DOI: 10.1016/j.neuroimage.2016.03.049.Peer-Reviewed Original Research