2024
Human brain state dynamics are highly reproducible and associated with neural and behavioral features
Lee K, Ji J, Fonteneau C, Berkovitch L, Rahmati M, Pan L, Repovš G, Krystal J, Murray J, Anticevic A. Human brain state dynamics are highly reproducible and associated with neural and behavioral features. PLOS Biology 2024, 22: e3002808. PMID: 39316635, PMCID: PMC11421804, DOI: 10.1371/journal.pbio.3002808.Peer-Reviewed Original ResearchConceptsCo-activation patternsResting-state functional magnetic resonance imagingFunctional magnetic resonance imagingBehavioral featuresNeural variationsMoment-to-moment changesSingle-subject levelBrain state dynamicsEmotion regulationHealthy young adultsBehavioral phenotypesCognitive functionSubstance useNeural activityNeuroimaging markersNeural featuresYoung adultsMagnetic resonance imagingCo-activationResonance imagingCo-variationNeuroimagingIndividualsEmotionsFunctional outcomes
2021
An altered balance of integrated and segregated brain activity is a marker of cognitive deficits following sleep deprivation
Cross NE, Pomares FB, Nguyen A, Perrault AA, Jegou A, Uji M, Lee K, Razavipour F, Bin Ka’b Ali O, Aydin U, Benali H, Grova C, Dang-Vu TT. An altered balance of integrated and segregated brain activity is a marker of cognitive deficits following sleep deprivation. PLOS Biology 2021, 19: e3001232. PMID: 34735431, PMCID: PMC8568176, DOI: 10.1371/journal.pbio.3001232.Peer-Reviewed Original ResearchConceptsSleep-deprived stateSleep deprivationCortical networksFunctional magnetic resonance imaging (fMRI) scansLarge-scale cortical networksCognitive impairmentSleep-deprived brainNight of SDHomeostatic sleep pressureExecutive tasksCognitive performanceTask performanceCognitive changesRegular nightBrain activityCognitive functionCognitive deficitsNetwork integrationInformation processingSleep pressureCortical activityBidirectional effectsConnectivity changesInterindividual differencesNonrapid eye movement sleep
2019
Automatic classification and removal of structured physiological noise for resting state functional connectivity MRI analysis
Lee K, Khoo HM, Fourcade C, Gotman J, Grova C. Automatic classification and removal of structured physiological noise for resting state functional connectivity MRI analysis. Magnetic Resonance Imaging 2019, 58: 97-107. PMID: 30695721, DOI: 10.1016/j.mri.2019.01.019.Peer-Reviewed Original ResearchConceptsReal dataNumber of atomsSubject-specific thresholdFunctional connectivity MRI analysisState networksAutomatic removal methodSpatial priorsSet of voxelsBootstrap resamplingSparse dictionary learningStepwise regression procedureNoiseHub analysisRegression procedureInter-network communicationNew methodAtomsBand-pass filteringTemporal correlationFluctuationsPriorsSparsityDictionary learningNetworkWhole-brain signals
2018
Disruption, emergence and lateralization of brain network hubs in mesial temporal lobe epilepsy
Lee K, Khoo HM, Lina JM, Dubeau F, Gotman J, Grova C. Disruption, emergence and lateralization of brain network hubs in mesial temporal lobe epilepsy. NeuroImage Clinical 2018, 20: 71-84. PMID: 30094158, PMCID: PMC6070692, DOI: 10.1016/j.nicl.2018.06.029.Peer-Reviewed Original ResearchConceptsMesial temporal lobe epilepsyTemporal lobe epilepsyLobe epilepsyState functional MRIDefault mode networkHealthy controlsBrain network hubsConnector hubsAbnormal hippocampusMotor networkHippocampal networkBrain regionsSalience networkFunctional MRIEpilepsyEpileptic subjectsMode networkLateralizationBrain networksDefault modeAbnormalitiesPathological disruptionHub reorganizationFunctional networksDisruption