2024
Outcomes of repeat conventional transarterial chemoembolization in patients with liver metastases
Ghabili K, Windham-Herman A, Konstantinidis M, Murali N, Borde T, Adam L, Laage-Gaupp F, Lin M, Chapiro J, Georgiades C, Nezami N. Outcomes of repeat conventional transarterial chemoembolization in patients with liver metastases. Annals Of Hepatology 2024, 29: 101529. PMID: 39033928, DOI: 10.1016/j.aohep.2024.101529.Peer-Reviewed Original ResearchConventional transarterial chemoembolizationLiver metastasesNeuroendocrine tumorsColorectal carcinomaTransarterial chemoembolizationOverall survivalLung cancerAssociated with improved patient survivalManagement of liver metastasesMetastatic liver lesionsSingle-institution analysisNonresponding patientsSurvival outcomesPatient survivalResponse assessmentTarget lesionsMetastasisLiver lesionsPatientsResponse rateChemoembolizationSurvivalLiverLesionsCancer
2016
Transarterial Chemoembolization for the Treatment of Advanced-Stage Hepatocellular Carcinoma
Zhao Y, Duran R, Chapiro J, Sohn JH, Sahu S, Fleckenstein F, Smolka S, Pawlik TM, Schernthaner R, Zhao L, Lee H, He S, Lin M, Geschwind JF. Transarterial Chemoembolization for the Treatment of Advanced-Stage Hepatocellular Carcinoma. Journal Of Gastrointestinal Surgery 2016, 20: 2002-2009. PMID: 27714643, PMCID: PMC5106296, DOI: 10.1007/s11605-016-3285-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAlpha-FetoproteinsAntineoplastic AgentsCarcinoma, HepatocellularChemoembolization, TherapeuticFemaleHumansLiver NeoplasmsMaleMiddle AgedNeoplasm StagingPortal VeinRetrospective StudiesRisk FactorsSurvival RateTreatment OutcomeTumor BurdenVenous ThrombosisYoung AdultConceptsPortal vein tumor thrombosisAdvanced-stage hepatocellular carcinomaTransarterial chemoembolizationHepatocellular carcinomaOverall survivalRisk scoreChild-Pugh A/BEastern Cooperative Oncology Group 0Child-Pugh B classLarge retrospective cohort studyRetrospective cohort studyAdvanced hepatocellular carcinomaStage hepatocellular carcinomaNumber of tumorsMedian OSCohort studyExtrahepatic metastasesSelect patientsTumor thrombosisImproved survivalPrognostic factorsTherapeutic recommendationsSurvival outcomesTumor sizeLonger survival
2014
Transarterial chemoembolization in soft-tissue sarcoma metastases to the liver – The use of imaging biomarkers as predictors of patient survival
Chapiro J, Duran R, Lin M, Mungo B, Schlachter T, Schernthaner R, Gorodetski B, Wang Z, Geschwind JF. Transarterial chemoembolization in soft-tissue sarcoma metastases to the liver – The use of imaging biomarkers as predictors of patient survival. European Journal Of Radiology 2014, 84: 424-430. PMID: 25542065, PMCID: PMC4315698, DOI: 10.1016/j.ejrad.2014.11.034.Peer-Reviewed Original ResearchConceptsMetastatic soft tissue sarcomaProgression-free survivalConventional transarterial chemoembolizationSoft tissue sarcomasOverall survivalTumor responseTransarterial chemoembolizationPatient survivalSafety profileCox proportional hazard ratio analysisProportional hazard ratio analysisSoft tissue sarcoma metastasisMedian overall survivalSalvage therapy optionsHazard ratio analysisReliable clinical dataSize-based criteriaEASL guidelinesModified RECISTIntraarterial therapySarcoma metastasisSurvival outcomesGrade IIIKaplan-MeierTherapy options