2018
Clinical Experience with Real-Time 3-D Guidance Based on C-Arm-Acquired Cone-Beam CT (CBCT) in Transjugular Intrahepatic Portosystemic Stent Shunt (TIPSS) Placement
Böning G, Lüdemann WM, Chapiro J, Jonczyk M, Hamm B, Günther RW, Gebauer B, Streitparth F. Clinical Experience with Real-Time 3-D Guidance Based on C-Arm-Acquired Cone-Beam CT (CBCT) in Transjugular Intrahepatic Portosystemic Stent Shunt (TIPSS) Placement. CardioVascular And Interventional Radiology 2018, 41: 1035-1042. PMID: 29541837, DOI: 10.1007/s00270-018-1877-4.Peer-Reviewed Original ResearchMeSH KeywordsCone-Beam Computed TomographyFeasibility StudiesFemaleFluoroscopyHepatic VeinsHumansHypertension, PortalImaging, Three-DimensionalMaleMiddle AgedPortal VeinPortasystemic Shunt, Transjugular IntrahepaticProspective StudiesPuncturesRadiography, InterventionalRetrospective StudiesStentsTreatment OutcomeUltrasonographyConceptsPuncture attemptsTIPSS placementTIPSS procedureProcedure timeTransjugular intrahepatic portosystemic stent shunt placementMean puncture timeSuccess ratePortal vein punctureSignificant differencesShunt placementPuncture timeConsecutive casesMedian numberProspective groupVein punctureUS guidanceClinical experienceControl groupCone beamStudy designCone-beam CTMean timeDoseCBCT guidancePatients
2017
Science to Practice: Molecular-targeted Drug Delivery in Combination with Radiofrequency Ablation of Liver Cancer: A Magic Bullet?
Adam LC, Murali N, Chapiro J, Geschwind JF. Science to Practice: Molecular-targeted Drug Delivery in Combination with Radiofrequency Ablation of Liver Cancer: A Magic Bullet? Radiology 2017, 285: 333-335. PMID: 29045226, PMCID: PMC5673055, DOI: 10.1148/radiol.2017171527.Peer-Reviewed Original ResearchConceptsRadiofrequency ablationRF ablationHepatocellular carcinoma mouse modelTechnical success rateSurvival end pointsChemotherapeutic drug concentrationsCarcinoma mouse modelAnimal tumor modelsTumor-penetrating peptideClinical outcomesTarget lesionsDrug delivery systemsLiver cancerMouse modelTumor modelEnd pointDrug concentrationsDrug deliverySuccess rateTumor treatmentToxic effectsDelivery systemAblationMagic bulletLesions