Long-term Therapeutic and Functional Outcomes With Organ Preservation for T4 Larynx and Hypopharynx Cancers
Rybkin A, Eita A, Kang J, Fiasconaro M, Zhang Z, Zakeri K, Yu Y, Chen L, Gelblum D, Tsai C, Riaz N, McBride S, Sherman E, Dunn L, Ho A, Cohen M, Cracchiolo J, Pfister D, Wong R, Lee N. Long-term Therapeutic and Functional Outcomes With Organ Preservation for T4 Larynx and Hypopharynx Cancers. International Journal Of Radiation Oncology • Biology • Physics 2021, 111: e365-e366. DOI: 10.1016/j.ijrobp.2021.07.1084.Peer-Reviewed Original ResearchPercutaneous endoscopic gastrostomyDisease-free survivalHypopharynx cancerLocoregional failureOverall survivalUnivariate analysisChemoradiation therapyRadiation therapySurgical candidatesDistant metastasisStage T4Functional outcomeMedian disease-free intervalAdequate supportive careOrgan preservation trialsYear OS ratesDefinitive radiation therapyDisease-free intervalKaplan-Meier methodLarynx groupSupportive careEndoscopic gastrostomyMethods PatientsNodal statusNonoperative management