1998
Autoimmune-Associated Congenital Heart Block: Demographics, Mortality, Morbidity and Recurrence Rates Obtained From a National Neonatal Lupus Registry
Buyon J, Hiebert R, Copel J, Craft J, Friedman D, Katholi M, Lee L, Provost T, Reichlin M, Rider L, Rupel A, Saleeb S, Weston W, Skovron M. Autoimmune-Associated Congenital Heart Block: Demographics, Mortality, Morbidity and Recurrence Rates Obtained From a National Neonatal Lupus Registry. Journal Of The American College Of Cardiology 1998, 31: 1658-1666. PMID: 9626848, DOI: 10.1016/s0735-1097(98)00161-2.Peer-Reviewed Original ResearchConceptsCongenital heart blockNeonatal lupus syndromeSSA/RoWeeks of gestationRecurrence rateLa antibodiesSubsequent pregnancySSA/Ro-SSB/La antibodiesAutoantibody-associated congenital heart blockDevelopment of CHBAnti-SSB/La antibodiesAnti-SSA/RoIsolated congenital heart blockClose echocardiographic monitoringLate second trimesterDays of lifeSSB/LaSufficient medical recordsMajor structural abnormalitiesMaternal autoantibodiesLupus syndromeNeonatal lupusEchocardiographic monitoringLupus RegistryHeart blockGlycosylated Hemoglobin in Insulin-Dependent Diabetes Mellitus Related to Preeclampsia
Hsu C, Hong S, Nickless N, Copel J. Glycosylated Hemoglobin in Insulin-Dependent Diabetes Mellitus Related to Preeclampsia. American Journal Of Perinatology 1998, 15: 199-202. PMID: 9572378, DOI: 10.1055/s-2007-993926.Peer-Reviewed Original ResearchConceptsIDDM pregnant womenMean HbA1c valuesIncidence of preeclampsiaHbA1c valuesPregnant womenGestational periodExact testInsulin-dependent diabetes mellitusHigher mean HbA1cPathogenesis of preeclampsiaWeeks of gestationFisher's exact testDifferent gestational periodsNormal mean valueIDDM pregnanciesMean HbA1cDiabetes mellitusWeeks' gestationGlycosylated hemoglobinInsulin-DependentRetrospective studyTrophoblastic invasionMedical recordsPreeclampsiaHigh incidence
1997
Circulating Thrombomodulin Levels and Clinical Correlates in Pregnant Diabetics
Magriples U, Hsu C, Chan D, Nickless N, Copel J. Circulating Thrombomodulin Levels and Clinical Correlates in Pregnant Diabetics. American Journal Of Perinatology 1997, 14: 605-608. PMID: 9605246, DOI: 10.1055/s-2008-1040762.Peer-Reviewed Original ResearchConceptsDuration of diabetesPregnant diabeticsClinical correlatesGroup 1Prospective cohort studyInsulin-dependent diabetesWeeks of gestationGestational diabetesCohort studyDiabetic pregnanciesSerum creatinineRenal diseaseThrombomodulin levelsEndothelial damageWhite classificationUnderwent determinationTM levelsDiabetesHbA1cDiabeticsThrombomodulinShort-term controlSignificant differencesDurationCorrelates
1995
In Utero identification and therapy of congenital heart block
Buyon J, Waltuck J, Kleinman C, Copel J. In Utero identification and therapy of congenital heart block. Lupus 1995, 4: 116-121. PMID: 7795614, DOI: 10.1177/096120339500400207.Peer-Reviewed Original ResearchConceptsCongenital heart blockWeeks of gestationHeart blockFluorinated steroidsDegree blockEarly third trimesterSecond-degree blockThird-degree blockDegree of blockDisease activityChart reviewPericardial effusionPrimary physicianThird trimesterSinus rhythmUtero identificationGestational periodPrenatal therapyFetal vulnerabilityPregnancyTiming of identificationTherapyMid secondWeeksPrednisone
1988
Prevention of Rh isoimmunization and treatment of the compromised fetus.
Grannum P, Copel J. Prevention of Rh isoimmunization and treatment of the compromised fetus. Seminars In Perinatology 1988, 12: 324-35. PMID: 3146812.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsFetal liver functionIntrauterine intravascular transfusionReversal of hydropsCorrection of anemiaWeeks of gestationSevere erythroblastosis fetalisNeonatal exchange transfusionProblems of prematurityNeonatal morbidityErythroblastosis fetalisIntravascular transfusionRh isoimmunizationExchange transfusionLiver functionFetal vasculatureIntravascular treatmentSevere diseaseTreatment teamPrompt correctionCentral veinTreatment centersTransfusionDifficult procedureTreatmentIsoimmunizationDevelopment of a benign intrapericardial tumor between 20 and 40 weeks of gestation
Weber H, Kleinman C, Hellenbrand W, Kopf G, Copel J. Development of a benign intrapericardial tumor between 20 and 40 weeks of gestation. Pediatric Cardiology 1988, 9: 153-156. PMID: 3186538, DOI: 10.1007/bf02080556.Peer-Reviewed Case Reports and Technical Notes