1997
The effect of intravascular blood transfusion on the flow velocity waveform of the portal venous system of the anemic fetus
d'Ancona R, Rahman F, Ozcan T, Copel J, Mari G. The effect of intravascular blood transfusion on the flow velocity waveform of the portal venous system of the anemic fetus. Ultrasound In Obstetrics And Gynecology 1997, 10: 333-337. PMID: 9444047, DOI: 10.1046/j.1469-0705.1997.10050333.x.Peer-Reviewed Original ResearchConceptsFlow velocity waveformsPortal venous systemAnemic fetusesVelocity waveformsPortal hypertensionIntravascular transfusionPortal veinVenous systemNormal fetusesIntravascular blood transfusionNon-pulsatile flowBlood transfusionRhesus alloimmunizationGestational agePulsatile patternTransfusionFetusesPresence of pulsatilityHypertensionIncreased numberCardiac cyclePulsatileVeinAlloimmunizationUteroIncrease of fetal hematocrit decreases the middle cerebral artery peak systolic velocity in pregnancies complicated by rhesus alloimmunization
Mari G, Rahman F, Olofsson P, Ozcan T, Copel J. Increase of fetal hematocrit decreases the middle cerebral artery peak systolic velocity in pregnancies complicated by rhesus alloimmunization. The Journal Of Maternal-Fetal Medicine 1997, 6: 206-208. PMID: 9260116, DOI: 10.1002/(sici)1520-6661(199707/08)6:4<206::aid-mfm3>3.0.co;2-n.Peer-Reviewed Original ResearchConceptsMiddle cerebral artery peak systolic velocityPeak systolic velocitySystolic velocityFetal hematocritTime of studyIntrauterine transfusionRed blood cellsFetal anemiaRhesus alloimmunizationGestational ageRh alloimmunizationDoppler ultrasoundBlood cellsHematocritAlloimmunizationPregnancyT-testP-valueDoppler measurementsStatistical comparisonTransfusionAnemiaDiagnosisIncrease of Fetal Hematocrit Decreases the Middle Cerebral Artery Peak Systolic Velocity in Pregnancies Complicated by Rhesus Alloimmunization
Mari G, Rahman F, Olofsson P, Ozcan T, Copel J. Increase of Fetal Hematocrit Decreases the Middle Cerebral Artery Peak Systolic Velocity in Pregnancies Complicated by Rhesus Alloimmunization. The Journal Of Maternal-Fetal Medicine 1997, 6: 206-208. DOI: 10.3109/14767059709161986.Peer-Reviewed Original ResearchMiddle cerebral artery peak systolic velocityPeak systolic velocitySystolic velocityFetal hematocritTime of studyIntrauterine transfusionRed blood cellsFetal anemiaRhesus alloimmunizationGestational ageRh alloimmunizationDoppler ultrasoundBlood cellsHematocritAlloimmunizationPregnancyT-testP-valueDoppler measurementsStatistical comparisonTransfusionAnemiaDiagnosis
1995
Management of the Rh-Sensitizeo Mother
Gollin Y, Copel J. Management of the Rh-Sensitizeo Mother. Clinics In Perinatology 1995, 22: 545-559. PMID: 8521681, DOI: 10.1016/s0095-5108(18)30268-9.ChaptersConceptsRh immune globulinManagement of complicationsRh D typingEarly referralIntrauterine transfusionImmune globulinRh isoimmunizationTertiary centerAnemic fetusesNeonatal careFetal bloodInvasive techniquesLung maturityPrompt identificationD typingClinical situationsOptimal managementFetusesMothersTransfusionComplicationsIsoimmunizationNeonatesNeonatologistsPerinatologists
1993
Fetal platelet counts correlate with the severity of the anemia in red-cell alloimmunization.
Saade G, Moise K, Copel J, Belfort M, Carpenter R. Fetal platelet counts correlate with the severity of the anemia in red-cell alloimmunization. Obstetrics And Gynecology 1993, 82: 987-91. PMID: 8233277.Peer-Reviewed Original ResearchConceptsRed cell alloimmunizationFetal platelet countPlatelet countNonhydropic fetusesBilirubin levelsReticulocyte countMaternal red cell alloimmunizationLow platelet countStudent's t-testFetal plateletsHydropic fetusesIntrauterine transfusionFetal anemiaGestational ageInitial transfusionAnemic fetusesHematopoietic stem cellsFetusesAlloimmunizationThrombocytopeniaTransfusionRegression analysisT-testAnemiaHydropic
1990
Invasive Fetal Assessment in the Antepartum Period
Copel J, Gullen M, Grannum P, Hohbins J. Invasive Fetal Assessment in the Antepartum Period. Obstetrics And Gynecology Clinics Of North America 1990, 17: 201-221. PMID: 2192320, DOI: 10.1016/s0889-8545(21)00473-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1989
Fetal cardiac output in the isoimmunized pregnancy: A pulsed Doppler-echocardiographic study of patients undergoing intravascular intrauterine transfusion
Copel J, Grannum P, Green J, Belanger K, Hanna N, Jaffe C, Hobbins J, Kleinman C. Fetal cardiac output in the isoimmunized pregnancy: A pulsed Doppler-echocardiographic study of patients undergoing intravascular intrauterine transfusion. American Journal Of Obstetrics And Gynecology 1989, 161: 361-365. PMID: 2504042, DOI: 10.1016/0002-9378(89)90520-6.Peer-Reviewed Original ResearchConceptsCardiac outputAnemic fetusesIsoimmunized pregnanciesCombined ventricular outputDoppler echocardiographic studyFetal cardiac outputHigh output stateHigh cardiac outputIntravascular intrauterine transfusionSevere isoimmunizationCardiac indexIntrauterine transfusionIntravascular transfusionWeeks' gestationVentricular outputDoppler assessmentAge-specific normsControl fetusesHydrops fetalisControl groupMechanisms of developmentFetusesUnaffected fetusesTransfusionPregnancy
1988
Prevention of Rh isoimmunization and treatment of the compromised fetus.
Grannum P, Copel J. Prevention of Rh isoimmunization and treatment of the compromised fetus. Seminars In Perinatology 1988, 12: 324-35. PMID: 3146812.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsFetal liver functionIntrauterine intravascular transfusionReversal of hydropsCorrection of anemiaWeeks of gestationSevere erythroblastosis fetalisNeonatal exchange transfusionProblems of prematurityNeonatal morbidityErythroblastosis fetalisIntravascular transfusionRh isoimmunizationExchange transfusionLiver functionFetal vasculatureIntravascular treatmentSevere diseaseTreatment teamPrompt correctionCentral veinTreatment centersTransfusionDifficult procedureTreatmentIsoimmunizationThe Use of Intravenous Pancuronium Bromide to Produce Fetal Paralysis During Intravascular Transfusion
Copel J, Granum P, Harrison D, Hobbins J, Marx G. The Use of Intravenous Pancuronium Bromide to Produce Fetal Paralysis During Intravascular Transfusion. Obstetric Anesthesia Digest 1988, 8: 71. DOI: 10.1097/00132582-198807000-00024.Peer-Reviewed Original ResearchIntravascular transfusionFetal paralysisFetal movementsPercutaneous umbilical blood samplingSevere erythroblastosis fetalisUmbilical blood samplingErythroblastosis fetalisIntravenous sedativesCord traumaVenous accessExchange transfusionPuncture siteBlood samplingPancuronium bromideMeans of treatmentTransfusionParalysisComplicationsSedativesFetalisPhlebotomyTraumaPulsed Doppler flow-velocity waveforms before and after intrauterine intravascular transfusion for severe erythroblastosis fetalis
Copel J, Grannum P, Belanger K, Green J, Hobbins J. Pulsed Doppler flow-velocity waveforms before and after intrauterine intravascular transfusion for severe erythroblastosis fetalis. American Journal Of Obstetrics And Gynecology 1988, 158: 768-774. PMID: 2966585, DOI: 10.1016/0002-9378(88)90070-1.Peer-Reviewed Original ResearchConceptsLate transfusionDoppler flow velocity waveformsIntrauterine intravascular transfusionFlow velocity waveformsSevere erythroblastosis fetalisFirst transfusionIntrauterine transfusionSubsequent transfusionsErythroblastosis fetalisIntravascular transfusionIsoimmunized pregnanciesDoppler studiesMaternal circulationDoppler ultrasoundTransfusionNormal fetusesHematocrit changesLack of changeHematocritDoppler parametersFetusesRapid volumeHydropsPregnancyFetalisThe use of intravenous pancuronium bromide to produce fetal paralysis during intravascular transfusion
Copel J, Grannum P, Harrison D, Hobbins J. The use of intravenous pancuronium bromide to produce fetal paralysis during intravascular transfusion. American Journal Of Obstetrics And Gynecology 1988, 158: 170-171. PMID: 3337166, DOI: 10.1016/0002-9378(88)90804-6.Peer-Reviewed Original Research