2021
To Expand the Evidence Base About Harms from Tests and Treatments
Korenstein D, Harris R, Elshaug AG, Ross JS, Morgan DJ, Cooper RJ, Cho HJ, Segal JB. To Expand the Evidence Base About Harms from Tests and Treatments. Journal Of General Internal Medicine 2021, 36: 2105-2110. PMID: 33479928, PMCID: PMC8298733, DOI: 10.1007/s11606-021-06597-9.Commentaries, Editorials and LettersReporting of harmsAssessment of harmsCare cascadeComorbid illnessesRange of severityTreatment burdenSocial determinantsHealthcare interventionsPatientsEvidence basePsychological distressPhysical impairmentPotential harmTreatmentRigorous evidenceHarmDomains of harmFinancial impactPsychological stateIllnessCliniciansImpairmentSeverityDisruptionDemographics
2019
Age-treatment subgroup analyses in Cochrane intervention reviews: a meta-epidemiological study
Liu P, Ioannidis JPA, Ross JS, Dhruva SS, Luxkaranayagam AT, Vasiliou V, Wallach JD. Age-treatment subgroup analyses in Cochrane intervention reviews: a meta-epidemiological study. BMC Medicine 2019, 17: 188. PMID: 31639007, PMCID: PMC6805640, DOI: 10.1186/s12916-019-1420-8.Peer-Reviewed Original ResearchConceptsCochrane intervention reviewsFormal interaction testingSubgroup analysisIntervention reviewsClinical practice resourcesInsufficient trial dataPotential subgroup differencesMeta-epidemiological studyIndividual subgroup analysisCochrane reviewAppropriate statistical testsClinical significanceClinical careSubgroup findingsTrial dataClinical resourcesHealthcare interventionsBiological rationaleAnalysis of ageTrialsIndividual trialsDemographic characteristicsPractice resourcesSubgroup differencesClinical translation