2019
Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome
Carrión V, Perez-Jaramillo J, Cordovez V, Tracanna V, de Hollander M, Ruiz-Buck D, Mendes L, van Ijcken W, Gomez-Exposito R, Elsayed S, Mohanraju P, Arifah A, van der Oost J, Paulson J, Mendes R, van Wezel G, Medema M, Raaijmakers J. Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome. Science 2019, 366: 606-612. PMID: 31672892, DOI: 10.1126/science.aaw9285.Peer-Reviewed Original ResearchMeSH KeywordsBacteriaBacterial Physiological PhenomenaBacteroidetesBeta vulgarisBiodiversityChitinasesDisease ResistanceEndophytesFlavobacteriumGenes, BacterialGenome, BacterialMetagenomeMicrobiotaMutagenesis, Site-DirectedPeptide SynthasesPlant DiseasesPlant RootsPolyketide SynthasesRhizoctoniaSoil MicrobiologyConceptsEndophytic root microbiomeNonribosomal peptide synthetasesGene clusterPolyketide synthaseRoot microbiomeBiosynthetic gene clusterInfection of plant rootsFungal root diseasesSite-directed mutagenesisPromote plant growthGenome reconstructionPeptide synthetasesRoot endosphereFunctional traitsNRPS-PKSFunctional diversityChitinase geneEndophytic consortiaFungal infectionsDisease suppressionRoot diseasePlant growthNetwork inferenceDisease-suppressive functionsPlant roots
2018
An Introduced Crop Plant Is Driving Diversification of the Virulent Bacterial Pathogen Erwinia tracheiphila
Shapiro L, Paulson J, Arnold B, Scully E, Zhaxybayeva O, Pierce N, Rocha J, Klepac-Ceraj V, Holton K, Kolter R. An Introduced Crop Plant Is Driving Diversification of the Virulent Bacterial Pathogen Erwinia tracheiphila. MBio 2018, 9: 10.1128/mbio.01307-18. PMID: 30279283, PMCID: PMC6168856, DOI: 10.1128/mbio.01307-18.Peer-Reviewed Original ResearchConceptsTemperate eastern North AmericaEastern North AmericaErwinia tracheiphila</i>,Host plant speciesPlant speciesCrop plantsCausal agent of bacterial wiltAgent of bacterial wiltVirulence gene repertoireLow genetic heterogeneityLarge-scale sequencingSusceptible to isolatesNorth AmericaDriving diversificationPhylogenomic analysisPopulation bottlenecksGenetic clustersEcological traitsIsolate collectionGene repertoirePopulation expansionGeographic rangeEvolutionary trajectoriesGenetic heterogeneityCausal agent