2024
Lubricating gel influence on vaginal microbiome sampling
Amitai Komem D, Hadar R, Paulson J, Mordechai Y, Eskandarian H, Efroni G, Amir A, Haberman Y, Tsur A. Lubricating gel influence on vaginal microbiome sampling. Scientific Reports 2024, 14: 18223. PMID: 39107405, PMCID: PMC11303677, DOI: 10.1038/s41598-024-68948-w.Peer-Reviewed Original ResearchConceptsMicrobial compositionVaginal samplesVaginal microbiome samplesBeta diversityVaginal microbiome studiesMicrobiome studiesMicrobiome samplesTaxa abundanceGynecological examinationPregnant womenLubricant gelReduce painMicrobial dataGel exposureEmergency roomSterile swabsEffect of gelMicrobial analysis
2021
Vaginal microbiome topic modeling of laboring Ugandan women with and without fever
Movassagh M, Bebell L, Burgoine K, Hehnly C, Zhang L, Moran K, Sheldon K, Sinnar S, Mbabazi-Kabachelor E, Kumbakumba E, Bazira J, Ochora M, Mulondo R, Nsubuga B, Weeks A, Gladstone M, Olupot-Olupot P, Ngonzi J, Roberts D, Meier F, Irizarry R, Broach J, Schiff S, Paulson J. Vaginal microbiome topic modeling of laboring Ugandan women with and without fever. Npj Biofilms And Microbiomes 2021, 7: 75. PMID: 34508087, PMCID: PMC8433417, DOI: 10.1038/s41522-021-00244-1.Peer-Reviewed Original ResearchConceptsIntrapartum feverClinical variablesHigh prevalenceVaginal microbiomeUgandan womenLonger labour durationMaternal clinical featuresYoung maternal ageDuration of pregnancyOnset of laborMicrobial communitiesVaginal microbial communitiesAfebrile mothersFebrile mothersPeripartum courseMaternal feverNeonatal outcomesLabor durationClinical featuresMaternal ageVaginal microbesFeverOutcome riskVeillonella genusMicrobiome influencesIntraventricular haemorrhage in a Ugandan cohort of low birth weight neonates: the IVHU study
MacLeod R, Paulson J, Okalany N, Okello F, Acom L, Ikiror J, Cowan F, Tann C, Dyet L, Hagmann C, Burgoine K. Intraventricular haemorrhage in a Ugandan cohort of low birth weight neonates: the IVHU study. BMC Pediatrics 2021, 21: 12. PMID: 33407279, PMCID: PMC7786968, DOI: 10.1186/s12887-020-02464-4.Peer-Reviewed Original ResearchConceptsRisk of intraventricular haemorrhageLow birth weight neonatesIntraventricular haemorrhageNeonatal unitAntenatal steroidsOdds ratioGestational ageCranial ultrasoundRisk factorsProspective cohort study of neonatesAssociated with intraventricular haemorrhageCohort study of neonatesDoses of antenatal steroidsPrevention of intraventricular haemorrhageRates of SGA neonatesSeverity of intraventricular haemorrhageDay 7Study of neonatesProspective cohort studyLow-income countriesDay of recruitmentModifiable risk factorsRegional Referral HospitalSGA neonatesVaginal delivery